Provisional Peer-Reviewed Toxicity Values for Toxaphene

Notice

EPA announced the release of a Provisional Peer-Reviewed Toxicity Value assessment for Technical Toxaphene, Weathered Toxaphene, and Toxaphene Congeners (CASRN 8001-35-2).

Abstract

Provisional Peer-Reviewed Toxicity Value (PPRTV) assessments support the EPA mission to protect human health and the environment by identifying and characterizing the health hazards of chemicals of concern to the Superfund and RCRA Programs, and providing an important source of toxicity information and toxicity values for such chemicals. PPRTVs [provisional oral reference doses (p-RfDs), inhalation reference concentrations (p-RfCs), cancer risk values, and screening values] are derived after a review of the relevant scientific literature and using Agency methodologies, practices, and guidance for the development of toxicity values. Other EPA programs or external parties who choose of their own initiative to use PPRTV values are advised that Superfund resources will not be used to respond to challenges of these PPRTVs used in a context outside of the EPA Superfund Program.

Impact/Purpose

Provisional Peer-Reviewed Toxicity Values (PPRTV) assessments are developed for use by the Agency's Office of Land and Emergency Management (OLEM) to support informed decisions in the Superfund program and at hazardous waste sites when a value is not available in the Integrated Risk Information System (IRIS) database

Citation

U.S. EPA. Provisional Peer-Reviewed Toxicity Values for Toxaphene. U.S. Environmental Protection Agency, Washington, DC, EPA/690/R-18/002, 2018.

History/Chronology

Date Description
01-Aug 2018EPA is announcing the release of a Provisional Peer-Reviewed Toxicity Value assessment for Technical Toxaphene, Weathered Toxaphene, and Toxaphene Congeners CASRN (8001-35-2) that was finalized and posted to the PPRTV website. Subchronic and chronic provisional RfDs were derived for Technical Toxaphene. Additionally, Appendix A of the assessment contains screening subchronic chronic provisional RfDs for Weathered Toxaphene.

This document has been reviewed in accordance with U.S. Environmental Protection Agency policy and approved for publication. Mention of trade names or commercial products does not constitute endorsement or recommendation for use.