Provisional Peer-Reviewed Toxicity Values for Lutetium

Notice

EPA announced the release of a Provisional Peer-Reviewed Toxicity Value assessment for Stable (Nonradioactive) Soluble Lutetium (CASRN 7439-94-3).

Abstract

Provisional Peer-Reviewed Toxicity Value (PPRTV) assessments support the EPA mission to protect human health and the environment by identifying and characterizing the health hazards of chemicals of concern to the Superfund and RCRA Programs, and providing an important source of toxicity information and toxicity values for such chemicals. PPRTVs [provisional oral reference doses (p-RfDs), inhalation reference concentrations (p-RfCs), cancer risk values, and screening values] are derived after a review of the relevant scientific literature and using Agency methodologies, practices, and guidance for the development of toxicity values. Other EPA programs or external parties who choose of their own initiative to use PPRTV values are advised that Superfund resources will not be used to respond to challenges of these PPRTVs used in a context outside of the EPA Superfund Program.

Impact/Purpose

PPRTVs are toxicity values derived for use in EPAs Superfund program when a value is not available in the IRIS database. Superfund site managers use PPRTVs in decision making for waste site clean ups.

Citation

U.S. EPA. Provisional Peer-Reviewed Toxicity Values for Lutetium. U.S. Environmental Protection Agency, Washington, DC, EPA/690/R-18/003, 2018.

History/Chronology

Date Description
01-Aug 2018EPA released the final Provisional Peer-Reviewed Toxicity Value assessment for Stable (Nonradioactive) Soluble Lutetium (CASRN 7439-94-3). A subchronic provisional RfD was derived. The 2007 PPRTV assessment for Lutetium was archived.

This document has been reviewed in accordance with U.S. Environmental Protection Agency policy and approved for publication. Mention of trade names or commercial products does not constitute endorsement or recommendation for use.