Grantee Research Project Results

Exposure Assessment and Intervention Project (EAIP)

EPA Grant Number: R829391C004
Subproject: this is subproject number 004 , established and managed by the Center Director under grant R829391
(EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
Center: Health Effects Institute (2005 — 2010)
Center Director: Greenbaum, Daniel S.
Title: Exposure Assessment and Intervention Project (EAIP)
Investigators: Lioy, Paul J.
Current Investigators: Lioy, Paul J. , Georgopoulos, Panos G. , Shalat, Stuart L. , Weisel, Clifford P.
Institution: University of Medicine and Dentistry of New Jersey
EPA Project Officer: Hahn, Intaek
Project Period: November 1, 2001 through October 31, 2006
RFA: Centers for Children's Environmental Health and Disease Prevention Research (2001) RFA Text | Recipients Lists
Research Category: Children's Health , Human Health

Objective:

The research being conducted within the Exposure Assessment and Intervention Project (EAIP) is continuing to address specific objectives associated with our first hypothesis: the unique behaviors of neurologically impaired children lead to higher exposures from single and multiple neurotoxicants in their personal or residential environment. The specific objectives of this research project are to: (1) implement a phased, community-based field study on neurotoxicant exposures and intervention strategies among community groups with families who have children identified with neurological disorders or deficits or diagnosed with the early indicators of such diseases; (2) document the exposure pathways that can lead to contact with neurotoxicants by the affected children using questionnaires and geographical information system (GIS) mapping (each will be used to qualitatively identify personal pathways or environmental sources, respectively); (3) implement an exposure measurement program based on the preceding analyses to establish the levels of specific neurotoxicants in the residence or personal environment of children at risk to neurological disorders or deficits; and (4) complete a detailed video assessment of the routine activities of these children and link directly with clinically based neurobehavioral assessments of children.

This year’s goal is to implement intervention strategies and educational programs within the affected families to reduce environmental residential exposures.

Publications and Presentations:

Publications have been submitted on this subproject: View all 11 publications for this subproject | View all 122 publications for this center

Journal Articles:

Journal Articles have been submitted on this subproject: View all 7 journal articles for this subproject | View all 85 journal articles for this center

Supplemental Keywords:

children’s health, disease and cumulative effects, ecological risk assessment, environmental chemistry, health risk assessment, susceptibility, sensitive population, genetic susceptibility, toxicology, assessment of exposure, assessment technology, autism, behavioral assessment, behavioral deficits, childhood learning, developmental disorders, developmental effects, environmental health hazard, environmental toxicant, exposure assessment, gene-environment interaction, neurodevelopmental, neurological development, neuropathological damage, neurotoxic, neurotoxicity, outreach and education, public health,, RFA, Scientific Discipline, Health, Health Risk Assessment, Risk Assessments, Susceptibility/Sensitive Population/Genetic Susceptibility, Ecological Risk Assessment, Children's Health, genetic susceptability, Biology, childhood learning, neurotoxic, behavioral assessment, gene-environment interaction, developmental effects, children, neurotoxicity, assessment of exposure, public health, behavioral deficits, environmental health hazard, autism, outreach and education, assessment technology, developmental disorders, exposure assessment, neurological development

Progress and Final Reports:

Main Center Abstract and Reports:

R829391 Health Effects Institute (2005 — 2010)

Subprojects under this Center: (EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
R829391C001 Neurotoxicant Effects on Cell Cycle Regulation of Neurogenesis
R829391C002 Adhesion and Repulsion Molecules in Developmental Neurotoxic Injury
R829391C003 Disruption of Ontogenic Development of Cognitive and Sensory Motor Skills
R829391C004 Exposure Assessment and Intervention Project (EAIP)
R829391C005 Clinical Sciences Project

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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.