Grantee Research Project Results
2017 Progress Report: Regional Air Pollution Mixtures: The past and future impacts of emissions controls and climate change on air quality and health
EPA Grant Number: R835872Center: Regional Air Pollution Mixtures
Center Director: Koutrakis, Petros
Title: Regional Air Pollution Mixtures: The past and future impacts of emissions controls and climate change on air quality and health
Investigators: Koutrakis, Petros , Schwartz, Joel , Coull, Brent , Dominici, Francesca , Selin, Noelle Eckley
Current Investigators: Koutrakis, Petros , Coull, Brent , Mickley, Loretta J. , Zigler, Corwin , Schwartz, Joel , Selin, Noelle Eckley
Institution: Harvard University , Massachusetts Institute of Technology
Current Institution: Harvard University , Massachusetts Institute of Technology , The University of Texas at Austin
EPA Project Officer: Keating, Terry
Project Period: December 1, 2015 through November 30, 2020 (Extended to November 30, 2022)
Project Period Covered by this Report: December 1, 2016 through November 30,2017
Project Amount: $10,000,000
RFA: Air, Climate And Energy (ACE) Centers: Science Supporting Solutions (2014) RFA Text | Recipients Lists
Research Category: Air , Climate Change , Air Quality and Air Toxics , Social Science , Airborne Particulate Matter Health Effects , Air Toxics , Human Health
Objective:
Project 1: Regional Air Pollution: Mixtures Characterization, Emission Inventories, Pollutant Trends, and Climate Impacts
The overall objective of Project 1 is to apply new approaches to characterize and analyze both historical and projected regional air pollution mixtures and emissions across the continental US. Project 1 characterizes temporal and spatial patterns of pollutant mixtures within and across regions. In addition, this project investigates factors influencing regional pollutant mixtures and predicts the impact of climate change on future air quality. Project 1 has four specific objectives.
Objective 1 is to compile comprehensive air pollution, weather, emissions, and GIS datasets for the entire continental US for the period 2000-2015. We will estimate gas and particle concentrations at a high spatial resolution by assimilating data from monitoring networks (compiled in collaboration with the Air Pollution Core), satellite platforms, air pollution models, and spatiotemporal statistical models. Objective 2 is to develop and make publically available a national PM2.5 emission inventory database of high spatial resolution (1 km) for 2000-2015. This will be achieved through the application of a novel methodology we developed that predicts point and area source emissions using aerosol optical thickness measured by satellite remote sensors. Objective 3 is to characterize spatial and temporal trends of pollutant mixtures. We will perform cluster analysis to group areas that exhibit distinct pollutant profiles or mixtures, referred to as “Air Pollution Regions,” then analyze their spatial patterns and temporal trends to investigate the impact of regulations, climate change, and modifiable factors on regional mixtures. Objective 4 is to forecast the impact of regional climate change on air quality for 2016-2040 using an ensemble of climate models. We will project the potential impact of climate change on regional pollutant mixtures and predict future regional air quality assuming no changes in anthropogenic emissions.
Project 2: Air Pollutant Mixtures in Eastern Massachusetts: Spatial Multi-resolution Analysis of Trends, Effects of Modifiable Factors, Climate, and Particle-induced Mortality
The objective of Project 2 is to characterize historical air pollution in Eastern Massachusetts at a high spatial resolution and identify modifiable factors responsible for observed changes in PM2.5 mass, emissions, elemental profiles, and ground air temperature. Project 2 investigates within-region variability of pollutant mixtures; examines the impact of modifiable factors on air quality; and evaluates the effectiveness of source control policies. Project 2 has four specific objectives.
Objective 1 is to use a novel, multi-resolution spatial analysis based on wavelet decomposition of high-resolution (1x1 km) remote sensing data on PM2.5 mass and ground air temperature to identify daily regional, sub-regional (urban background) and locally generated variation in these fields. Objective 2 is to develop and apply spatiotemporal regression models to (a) quantify the impact of modifiable factors, including transportation, heating fuel use, energy, urban planning, PM2.5 emissions, population statistics, and policy interventions, on (i) sub-regional and local variation in PM2.5 mass and ground air temperature and (ii) high resolution local estimates of PM2.5 emissions; (b) identify locations in which these impacts are greatest; and (c) identify lag times between implementation of a given control strategy and decreases in PM2.5 emissions and mass. Objective 3 is to implement a novel multi-resolution correlation analysis to identify PM2.5 elemental profiles that vary at regional, sub-regional, and local scales, and apply spatiotemporal regression models to these profiles to identify modifiable factors driving urban background and local variability in PM2.5 composition. And Objective 4 is to use the spatial scale-specific (regional, sub-regional, and local) temporal variability in PM2.5 mass and the PM2.5 elemental profiles to identify source types (regional, urban background, or local) and the composition of their emissions driving pollution-induced mortality in Eastern Massachusetts. This project relies on existing remote-sensing satellite data, ambient monitoring data collected from numerous sampling campaigns (including the HSPH Boston Supersite daily samples collected since 1998 and samples from 600 locations), as well as new data collected from 2015-2018 in Eastern Massachusetts.
Project 3: Causal Estimates of Effects of Regional and National Pollution Mixtures on Health: Providing Tools for Policy Makers
The objective of Project 3 is to estimate the causal impact of changes in pollution concentrations and mixtures (annual averages and daily patterns), how they vary by modifiable factors, the causal impacts of AQI triggers, how climate change that occurred in the last 20 years has increased mortality due to pollution, how temperature modifies the effects of pollution mixtures, and how these effects change for exposures less than the ambient standards for PM2.5. Project 3 provides region-specific causal estimates of effects of pollution mixtures; provides causal estimates of the impact of modifiable factors; assesses the impact of climate change on mortality from air pollution using historic data, avoiding any dependence on the accuracy of climate models; and provides causal estimates of how changes in particular components of mixtures affect mortality, to guide region-specific policy decisions on air pollution. Project 3 has five specific objectives.
Objective 1 is to identify and estimate the causal effects of air pollution and mixtures on human health. We will use methods of causal inference to a) identify the causal effects of regional annual air pollution concentration fluctuations and temperature fluctuations during the last 16 years on human health; b) identify the causal effects of regional air pollution trends during the last 16 years; c) identify the causal effects of pollution mixtures, sources, and emissions on health; d) identify differences in these effects by modifiable factors; e) conduct a national risk assessment on the causal impact of past pollution on mortality, including the regional differences in concentration-response; and f) investigate the causal impact of AQI thresholds for PM2.5 and O3 due to behavioral adaptation. Objective 2 is to analyze relative acute toxicity of pollution mixtures. We will a) examine spatial (across regions) and temporal heterogeneity in the acute toxicity of pollution mixtures and emissions to understand which source types, atmospheric processes, and exposure factors influence the toxicity of regional mixtures and b) use causal mediation analysis to determine how much of the temperature effect on mortality is mediated by its effects of pollution concentrations, and how that varies regionally. This will allow us to obtain local- and region specific estimates of future health effects and the benefits of changes in modifiable factors and adaptation. Objective 3 is to estimate the excess deaths resulting from air pollutant concentration changes due to weather changes in the last 20 years. We will demonstrate the extent to which public health impacts of climate change through pollution have already occurred, by using causal estimates of C-R relationships. Regional health impacts will be assessed using region-specific mortality risks estimates from Objective 1. Objective 4 is to estimate the causal health effects of low-level air pollution exposure. Specifically, we will examine whether the observed effects at low pollutant levels are due to the synergistic effect of multiple pollutants (mixtures) present at low levels. And Objective 5 is to investigate air pollution-related health effects at high and low temperatures. We will examine this by region and determine whether populations, especially those that include sensitive individuals, adapt to abrupt temperature changes.
Project 4: A Causal Inference Framework to Support Policy Decisions by Evaluating the Effectiveness of Past Air Pollution Control Strategies for the Entire United States
The overall objective of Project 4 is to develop a new methodological framework rooted in principles of causal inference to investigate the effectiveness of specific control strategies on impacting the largest power-generating units in the United States. In Project 4, we combine state-of-the-art atmospheric modeling, causal inference methods, and national data sets to conduct accountability research; that is, research that characterizes causal effects of well-defined regulatory actions at power plants on: 1) emissions; 2) air quality across distant locations in accordance with atmospheric fate, transport, and other factors; and 3) health outcomes. Project 4 has 4 specific objectives.
Objective 1 is to develop a national database on emissions control technologies employed at a large number of power-generating units in the US linked with: continuous emissions monitoring, ambient air quality monitoring, weather, population demographics, and Medicare hospitalization and mortality outcomes for the period 1995 to 2015. Objective 2 is to estimate and compare the causal effects of past control strategies implemented at the largest power-generating facilities on SO2, NOx, CO2, and PM2.5 emissions and population exposure to criteria pollutants (PM2.5 and O3) for the entire US for the period 2000 to 2015. This requires integrating new statistical methods for causal inference with atmospheric chemistry models of how changes in emissions impact ambient exposures across distant locations in accordance with atmospheric fate, transport, and other factors. Objective 3 is to estimate the causal effects of past control strategies implemented at the largest power-generating facilities on mortality and morbidity in the entire US both locally and nationally, and compare the differential health impact of different control strategies. And Objective 4 is to develop approaches for mediation analysis that will quantify the extent to which causal effects of regulatory actions on health outcomes can be attributable to changes in targeted modifiable factors (e.g., emissions, targeted pollutants), as opposed to being driven by co-benefits to other factors.
Project 5: Projecting and Quantifying Future Changes in Socioeconomic Drivers of Air Pollution and its Health-Related Impacts
Project 5 investigates future changes in regional air pollution characteristics as a result of technological and societal changes. We will quantify the future implications of technologies and efficiency improvements in the energy and transportation sectors on regional differences in air pollution impacts. Selected case studies assess, inter alia, the environmental and health benefits of choices in state and regional carbon policy implementation relevant to recently proposed carbon dioxide emission reductions from the energy sector. We will examine the health-related benefits of reducing concentrations of ozone and particulate matter, as well as changing regional air pollution mixtures including air toxics.
Progress Summary:
Project 1: Regional Air Pollution: Mixtures Characterization, Emission Inventories, Pollutant Trends, and Climate Impacts
In year 2, our efforts were focused on Objectives 1, 2 and 4.
Objective 1. We conducted a 3-year GEOS-Chem simulation for 2013-2015 to provide continuous information on ozone and PM concentrations for the purpose of epidemiological analyses. The simulation has 0.5°x0.625° resolution over North America and is driven by MERRA-2 assimilated meteorological data from the NASA Global Modeling and Assimilation Office (GMAO). We used the most recent benchmarked version of GEOS-Chem (v11-2-c) including detailed ozone-aerosol chemistry. That version was previously evaluated in detail with observations of ozone, PM, and their precursors over the Southeast US during the SOAS and SEAC4RS campaigns in summer 2013. The evaluation tested a new model scheme for isoprene secondary organic aerosol (SOA) and was successful in simulating overall organic aerosol levels. Observations of NOx and its oxidation products showed that NOx emissions in the EPA National Emission Inventory (NEI) were biased high by up to 50% (depending on errors in soil NOx emissions), and implementation of this correction provided an improved simulation of ozone. All these developments were incorporated in the GEOS-Chem version used for our multi-year EPA ACE simulation. Long-term relative trends of NEI emissions were applied over the duration of the simulation period.
The simulation was completed in November 2017 and results were provided to Prof. Joel Schwartz’s group (Project 3) for epidemiological analyses. The GEOS-Chem output archive includes daily surface concentrations of maximum daily 8-hr average (MDA8) ozone, NO2, PM2.5 and its components, and aerosol optical depth (AOD). This was a major deliverable for the project.
Objective 2. Focus during year 2 has been on Particle Emission Inventory using Remote Sensing (PEIRS) to construct spatially- and temporally-resolved emission inventories for PM2.5. Our efforts on this objective during Year 2 have included extending our work to cover more of the USA and the complete targeted time span. Using a mass balance approach, we converted the daily PM2.5 fields to a net addition (reflecting contributions of primary emission, secondary formation, and losses due to deposition) within each 1x1 km grid cell. We have also devoted significant effort toward improving our models. Because the spatial scale of primary PM2.5 emissions is smaller than the scale of secondary formation, discrete wavelet decomposition can be used to separate the net addition fields into two parts: the high frequency fraction and low-frequency fraction. This allows us to better assess primary emissions versus secondary formation and regional emissions.
Objective 4. We wrapped up work begun on statistical models to investigate the meteorological drivers of inter-annual to multidecadal variability of air quality, including ozone and fine particulate matter (PM2.5), in the United States. We examined processes involving climate patterns at different spatial scales, including that of local weather (~100 km), synoptic circulation (~1,000 km) and large-scale climate patterns (~10,000 km).
In Shen et al. (2017a), we first constructed a statistical model for relating observed PM2.5 to regional meteorology across the United States from 1999 to 2013. We applied the model to an ensemble of global climate models under the RCP4.5 scenario, predicting an annual mean increase of 0.4-1.4 mg/m3 of PM2.5 in the eastern United States by the 2050s. This prediction assumes present-day anthropogenic sources of PM2.5. Mean summertime PM2.5 increases as much as 2-3 mg/m3 in the eastern United States due to faster oxidation rates and greater mass of organic aerosols from biogenic emissions.
In Shen and Mickley (2017a), we developed a seasonal prediction model for surface ozone in the East. The model predicts June–July–August (JJA) daily maximum 8-h average (MDA8) ozone concentrations using large-scale climate patterns during the previous spring. In Shen and Mickley (2017b), we examined the influence of El Nino on U.S. surface ozone from 1980 to 2016. We found that each standard deviation increase in the Niño 1+2 index is associated with an increase of 1–2 ppbv ozone in the Atlantic states and a decrease of 0.5–2 ppbv ozone in the south central states. These influences can be predicted 4 months in advance. Finally, in Shen et al. (2017b), we found that U.S. summertime air quality displays strong dependence on North Atlantic sea surface temperatures, resulting from large-scale ocean-atmosphere interactions. We further identified multidecadal variability in surface air quality driven by the Atlantic Multidecadal Oscillation.
Taken together, these studies (1) improve understanding of current trends in U.S. air quality, (2) provide a means to evaluate current chemistry dynamical models such as GEOS-Chem, and (3) allow projection of air quality trends into the future, given meteorological fields from global climate models.
Project 2: Air Pollutant Mixtures in Eastern Massachusetts: Spatial Multi-resolution Analysis of Trends, Effects of Modifiable Factors, Climate, and Particle-induced Mortality
This past year we finalized several manuscripts that ultimately appeared in print. Highlights include:
Black Carbon (BC), an indicator of particles generated from traffic sources, has been associated with a number of health effects however due to its high spatial variability its concentration is difficult to estimate. We previously fit a model estimating BC concentrations in the greater Boston area; however this model was built using limited monitoring data and could not capture the complex spatio-temporal patterns of ambient BC. In order to improve our predictive ability, we obtained more data for a total of 24,301 measurements from 368 monitors over a 12 year period in Massachusetts, Rhode Island and New Hampshire. We also used Nu-Support Vector Regression (nu-SVR) - a machine learning technique which incorporates nonlinear terms and higher order interactions, with appropriate regularization of parameter estimates. We then used a generalized additive model to refit the residuals from the nu-SVR and added the residual predictions to our earlier estimates. Both spatial and temporal predictors were included in the model which allowed us to capture the change in spatial patterns of BC over time. The 10 fold cross validated (CV) R2 of the model was good in both cold (10-fold CV R2 = 0.87) and warm seasons (CV R2 = 0.79). We have successfully built a model that can be used to estimate short and long-term exposures to BC in MA, RI and Southern NH. This work was published in Environmental Research (Abu Awad 2017).
Fine particulate matter (PM2.5) measured at a given location is a mix of pollution generated locally and pollution traveling long distances in the atmosphere. Therefore, the identification of spatial scales associated with health effects can inform on pollution sources responsible for these effects, resulting in more targeted regulatory policy. We proposed a two-dimensional wavelet decomposition that alleviates restrictive assumptions required for standard wavelet decompositions. Using this method we decomposed daily surfaces of PM2.5 to identify which scales of pollution are most associated with adverse health outcomes. A key feature of the approach is that it can remove the purely temporal component of variability in PM2.5 levels and calculate effect estimates derived solely from spatial contrasts. This eliminates the potential for unmeasured confounding of the exposure - outcome associations by temporal factors, such as season. We applied our method to a study of birth weights in Massachusetts, U.S.A from 2003-2008 and find that both local and urban sources of pollution are strongly negatively associated with birth weight. Results also suggest that failure to eliminate temporal confounding in previous analyses attenuated the overall effect estimate towards zero, with the effect estimate growing in magnitude once this source of variability is removed. This work was published in the Annals of Applied Statistics this past year (Antonelli et al. 2017).
Recent interest focuses on identifying critical windows of vulnerability associated with prenatal exposure to air pollution during pregnancy. An analysis based on a distributed lag model (DLM) can yield estimates of a critical window different from those from an analysis that regresses the outcome on each of the three trimester average exposures (TAEs), which is the standard approach typically used in the environmental health literature. Using a simulation study, we assessed bias in estimates of critical windows obtained using three regression approaches: 1) three separate models to estimate the association with each of the three TAEs; 2) a single model to jointly estimate the association between the outcome and all three TAEs; and 3) a DLM. We use weekly fine particulate matter (PM2.5) exposure data for 238 births in a Boston-area birth cohort and a simulated outcome and time-varying exposure effect. Estimates using separate models for each TAE were biased and identified incorrect windows. This bias arose from seasonal trends in PM2.5 that induce correlation between TAEs. Including all TAEs into one model reduced bias. DLM produced estimates that were unbiased and added flexibility to identify critical windows. Analysis of body mass index z-score and fat mass in the same cohort highlights inconsistent estimates from the three methods. This work was published in American Journal of Epidemiology this past year (Wilson et al. 2017a).
In related work, simultaneous estimation of windows of vulnerability and effect heterogeneity is typically accomplished by fitting a distributed lag model (DLM) stratified by subgroup. However, this does not allow for subgroups to have the same window of vulnerability but different effects within the window or to have different windows but the same within-window effect, which can make full characterization of effect heterogeneity difficult. We proposed a new approach that partitions the DLM into a constrained functional predictor that estimates windows of vulnerability and a scalar effect size that estimates the effect within the window. The proposed method allows for heterogeneity in only the window of vulnerability, only the effect within the window, or in both by allowing each component to be either shared or differ across groups. We used the proposed method to estimate windows of vulnerability in the association between prenatal exposures to fine particulate matter (PM_2.5) and each of birth weight and asthma incidence, and to estimate how these associations vary by sex and maternal obesity status, in a Boston-area prospective pre-birth cohort study (Wilson et al. 2017b). These methods have been implemented in several other analyses of prenatal, sex-specific critical windows of air pollution exposure on health outcomes in children (Brunst et al. 2017; Chiu et al. 2017; Lee 2017).
Project 3: Causal Estimates of Effects of Regional and National Pollution Mixtures on Health: Providing Tools for Policy Makers
The past year was a very successful year for our project. We published two major nationwide studies on the acute and chronic effects of exposure to PM2.5 and ozone. In Di et al we analyzed the entire Medicare population and looked at the effect of annual average exposure to PM2.5 and ozone on survival in a cohort study. This study included all Medicare beneficiaries for the first time, and importantly, people who live in small cities, towns, and rural areas as well as larger urban areas. We found a highly significant association between PM2.5 and ozone and mortality rates. Importantly, we had 32 million people whose exposure was below the current ambient air quality standard of 12 μg/m3, with 248 million person years of follow-up, and in analyses restricted to just those observations, we found a highly significant association with PM2.5, demonstrating that the mortality effects continue to concentrations well below the current standard.
In the second paper, we performed a case-crossover analysis looking at ozone exposure and PM2.5 exposure and the acute risk of mortality, again, in the entire Medicare population. Once more, both associations were highly significant, and continued well below current air quality standards with no evidence of a threshold.
In Abu Awad et al we extended a BC model we had previously fit in eastern MA to include all of Massachusetts as well as Rhode Island and Southern New Hampshire. We also improved the model by using machine learning, providing estimates with smaller mean squared error on left out monitors, and extended the time period up to 2012. Using this updated exposure we then published a paper (Kingsley 2017) using that exposure (and our PM2.5 model) to look at the role of particles in preterm birth.
In Dai 2017 we used the measurements of particle metal components from our central site to examine the effects of different kinds of particles on DNA methylation in an agnostic analysis. We observed 20 Bonferroni significant (P-value < 9.4£ 10¡9) CpGs for Fe, 8 for Ni, and 1 for V, demonstrating that metal particles influence DNA methylation.
In Wang 2017 we developed a novel method for assessing adaptation to heat waves using temperature and mortality data from 1961 onwards and applied that to the estimated temperatures under 4 different greenhouse gas emissions scenarios from 21 different global climate models. We found adaptation continued up until a maximum temperature. Hence in the Northern US, heat wave related mortality is expected to fall (taking into account continued adaptation) but in the Southeastern US, it is expected to increase as adaptation reaches its limits.
In Nwanaji-Enwerem et al, 2017, we made the important finding that DNA methylation age, a measure of biological aging, was increased by exposure to PM2.5 (estimated at home addresses with one of our models) and that this effect was modified by genetic variations in genes related to miRNA processing. This effect varied by genotype from between 1 and 3 years of additional aging equivalent as PM2.5 went from 8 to 12 μg/m3, again showing effects below ambient standards.
In another paper by Nwanaji-Enwerem we examined PM2.5 components from a chemical transport model as predictors of DNA methylation age. We found that sulfate and ammonium components were associated with increased methylation age, independent of PM2.5 mass. This held when restricted to PM2.5 concentrations below 12.
In Peng 2017 we showed that short term increases in air temperature resulted in increased lesions in mitochondrial DNA.
In Prada 2017 we reported that PM2.5 from our models was associated with hospital admissions for osteoporosis-related fractures in the Medicare cohort. Simultaneously, in a more detailed cohort in the Boston are we followed a cohort of participants longitudinally and for that both black carbon (from the model above) and PM2.5 were associated with lower serum parathyroid hormone, and black carbon was associated with higher bone mineral density loss over time in multiple sites.
In Schwartz 2017 we addressed the causality of the association between PM2.5 and NO2 with daily deaths, but implementing an instrumental variable analysis for local particles, as well as a negative exposure control. We found significant effects of both pollutants. The instrument was a combination of the height of the planetary boundary layer and wind speed, which influence local pollution concentrations, but are unlikely to otherwise influence daily deaths.
We followed up with another causal modeling approach (Wang 2017), this time for cohort analysis of long term exposure. Using the Medicare population of the Southeast as our cohort, we developed a doubly robust additive hazard model to study survival versus exposure. That is, like a tradition causal model, it give causal estimates if the model for exposure given the covariates is correct, however, it also gives causal estimates if the model for mortality given the covariates is correct. We found a highly significant, causal estimate for the effects of PM2.5 on life expectancy. Separately, we fit a more traditional proportionate hazard model in the same population to examine effect modification. We found higher effects among males, non-whites, persons eligible for Medicaid as well as Medicare, and persons living in neighborhoods with lower SES.
In addition to these publications, we continued to update our pollution models in terms of improving modeling methods and extending the time frame. We expect to produce updated estimates to 2016 for BC, PM2.5, and O3 by early summer.
Project 4: A Causal Inference Framework to Support Policy Decisions by Evaluating the Effectiveness of Past Air Pollution Control Strategies for the Entire United States
The bulk of progress during year 2 for Project 4 has fallen into 5 categories:
- Refining the national database on power plants, emissions, ambient pollution, population demographics, and health outcomes among Medicare beneficiaries. Efforts have included the acquisition of a curated database of census-like variables for as all the years available from ESRI Business Analyst (annual data, 2000-present). We also bought two reserved-usage Dell servers and 30TB of secure storage, within the Harvard RCE high-performance computing cluster (https://rce-docs.hmdc.harvard.edu/).
- New reduced-form scalable strategies to produce source-receptor matrices linking individual power plants to US zip codes. We have continued to refine our strategy based on the Hybrid Single Particle Lagrangian Integrated Trajectory model. In collaboration with the Carnegie Mellon/UW ACE Center, we have initiated a new strategy based on the recently-proposed Intervention Model for Air Pollution (InMAP) to generate similar source-receptor matrices. We have also explored purely statistical strategies based on scalable generalized additive models of daily emissions and pollution time series. Methods are being compared/validated against each other and against observations, and also being used for intervention analyses.
- Statistical methods development. The various methods for obtaining source-receptor models have been used as inputs into novel statistical methods development, including development of new methodology for bipartite causal inference with interference. We have also continued to pursue methods for general causal inference, multiple mediating variables, spatial confounding adjustment, uncertainty in propensity score “design” stage, causal inference with interference, model averaging for confounder selection, measurement error, causal exposure-response estimation, and statistical network analysis, all in the context of evaluating power plant regulations.
- Environmental and Epidemiological Analyses. The above methods development has been in service of analyses of air pollution interventions including analyses of the health benefits of PM nonattainment designations, evaluation of selective (non) catalytic reduction systems for reducing NOx emissions and ambient ozone, mediation analyses of how scrubbers on coal-fired power plants reduce ambient PM, evaluation of the health effects associated with air pollution derived specifically from coal-fired power plants, flexible estimation of causal exposure-response relationships at low levels of ambient pollution.
- Software. Publications are paired with reproducible R scripts and/or packages, hosted on digital repositories. We deployed a customized version of the SplitR package (the R interface to HYSPLIT) on our new servers. We also developed and deployed the rinmap R package to generate source-receptor matrices using inMAP.
Project 5: Projecting and Quantifying Future Changes in Socioeconomic Drivers of Air Pollution and its Health-Related Impacts
Work on Project 5 during the reporting year has been focused on three main goals. The first has been to continue the sector-, emitter-, and receiver-specific analysis of past and present emissions within the US. To that end, we have completed a study quantifying the fine particulate matter (PM2.5) pollution exchange between the US states. Using the adjoint of the GEOS-Chem chemistry transport model, the state-level population exposure sensitivities to PM2.5 precursor emissions in all other states in the continental US have been calculated, including “domestic” emissions (same-state). The EPA’s National Emissions Inventories from 2004 onwards have been leveraged to provide a high-quality input dataset, while the Sparse Matrix Operator Kernel (SMOKE) Modeling System has been applied to group individual sources into seven sectors: electric power generation, industry, commercial/residential, and four modes of transportation: road, marine, rail and aviation. By applying the estimated emissions distribution to the calculated sensitivity matrices, we have generated impact source-receptor matrices for every pair of states within the contiguous US. This allows each state to estimate not only the degree to which air quality degradation is a result of emissions from a specific sector, but also the degree to which those impacts are within the legislative control of that state. Furthermore, estimates were made for multiple years from 2004 to 2014, showing that while the overall impacts of anthropogenic emissions have been decreasing, the impact per unit emitted has been increasing. This speaks directly to objective 4, by quantifying the role that changes in the mix and magnitude of anthropogenic emissions has affected and will continue to affect local air quality. It also provides crucial information for the evaluation of the impact of related energy policy, by giving a numerical estimate of the co-benefits or tradeoffs which might be incurred if other policies penalize or incentivize specific states or industrial sectors. A manuscript based on this work has been submitted for publication and is currently under peer review.
The second focus area has been on objectives 2 and 3, through extending and applying our economic analysis capabilities. We have made additional enhancements to the U.S. Regional Energy Policy Model (USREP) which will allow us to model energy policies and their impacts with greater precision. These enhancements include the incorporation into USREP of detailed data on the relative costs of energy technologies. On the basis of these changes, we have designed and implemented a new version of USREP (currently in the final stages of development) which models a larger number of sub-national regions and allows for the simulation of state-level energy policies. USREP’s comprehensive coverage of the U.S. economy allows us to account for the broad impacts that energy policies can have on the economy. We are using this model in combination with reduced-form air quality tools (including the source-receptor matrices described above) to simulate energy policies and estimate their effects with regards to both the economy and air quality. This modeling framework provides self-consistent estimates of the costs and benefits of U.S. energy policies. We are also exploring comparisons with other reduced-form tools including the Intervention Model for Air Pollution (InMAP), in collaboration with the Marshall group at the University of Washington.
We have continued an effort to develop a large ensemble of climate simulations relying on the MIT Integrated Global System Model, more specifically a version coupled with the NCAR Community Atmospheric Model, to provide the core basis to examine the impact of future climate change on air quality and health. This specifically serves project objectives 1, 3, and 5. This ensemble builds upon the work by Garcia-Menendez et al. (2015), which investigated the air quality and health benefits from avoided climate change under greenhouse gas mitigation using one of the largest ensemble of climate simulations to drive the global and three-dimensional atmospheric chemistry model CAM-Chem. Because the ensemble includes both multi-decadal and initial condition perturbations, leading to more than 1000 years of simulation air quality, Garcia-Menendez et al. (2017) further examined the impact of natural variability on the robustness of projections of climate change impacts on U.S. ozone pollution. However, this ensemble was designed as time slices, with three 30-year time periods (1981-2010, 2036-2065 and 2086-2115). Thus it does not allow a proper time of emergence analysis, which instead requires transient simulations, to determine how many years it will take for climate change, greenhouse mitigation policies or air pollution policies to be detected, given the large year-to-year variations in the climate and air quality systems. For this reason, we are running a new large ensemble of transient climate simulations to answer these questions. In addition, since the ongoing project will use the GEOS-Chem atmospheric chemistry model instead of the CAM-Chem model, we have modified the source code of the climate model to provide the appropriate input data for the project. The updated climate model is now production ready and the runs will start momentarily. A new, high-performance version of GEOS-Chem (GCHP) has now been adapted to accept these fields, allowing rapid and responsive air quality and composition simulations to be incorporated as a component in the modeling chain.
Future Activities:
During Year 3, the Center will continue with activities discussed above. Specific Project activities for Year 3 are described in the Project Progress Reports included in later sections. Additional planned Center activities during Year 2 include our second annual SAC meeting, which is scheduled for May 30-31, 2018.
Project 1: Regional Air Pollution: Mixtures Characterization, Emission Inventories, Pollutant Trends, and Climate Impacts
We have now begun to use the archive of GEOS-Chem output generated for Objective 1 to address major questions that arose from our SOAS and SEAC4RS work. These questions, which have subsequently been supported by other analyses, are: why are NEI NOx emissions so overestimated, and can satellite (OMI) observations of tropospheric NO2 columns provide useful constraints on the patterns of overestimates by sector, region, and season? Previous studies have shown consistency between 2005-present NEI NOx emission trends and OMI NO2 trends; but that then implies the NEI overestimate of NOx emissions has persisted for over a decade. We plan to compare the detailed patterns observed by OMI to those seen in the GEOS-Chem simulation to identify specific source sectors (including soils) and regions that may be responsible for the overestimate, and the extent to which this overestimate persists across seasons. This work will constitute the final thesis project for Harvard PhD student Rachel Silvern.
During Year 3, we also expect to focus intensively on Objective 2, using PEIRS with wavelet decomposition to separate the high frequency/primary emissions from the net addition fields.
Project 2: Air Pollutant Mixtures in Eastern Massachusetts: Spatial Multi-resolution Analysis of Trends, Effects of Modifiable Factors, Climate, and Particle-induced Mortality
We will focus on two areas of research recommended by the Center’s Scientific Advisory Council last May. These are better characterization of uncertainty associated with exposure-prediction models based on remote-sensing satellite data, and the application of the methods applied in Objective 1 to mortality data, which is objective 4 in the proposal. More details are as follows:
In the last few years, several research teams have developed distinct spatio-temporal models (exposure models) to predict ambient air pollution exposures of study participants even in areas where air pollution monitors are sparse. Use of these exposure models has led to strong evidence of air pollution-related adverse health effects, and in some instances, evidence of heterogeneity of these health effects across sub-populations. A significant limitation, however, is that these health effect estimates and their statistical uncertainty are based on the very strong assumption that a single exposure model is correct. Over the coming year we will be evaluating the impact of this assumption and developing a way to characterize uncertainty associated with exposure prediction model choice. Our preliminary results show that even when distinct exposure models predict similarly well, the spatio-temporal pattern of their errors might differ significantly. These complex error structures can lead to misleading evidence of effect heterogeneity across sub-populations, which in turn could be wrongly attributed to other factors that vary in a similar manner either in space (e.g. rural vs. urban) or time (e.g. by season).
Ultimately, we will develop a novel ensemble model framework to integrate information across multiple existing air pollution prediction models across the United States and, for the first time, to comprehensively quantify the uncertainty associated with air pollution exposure assessment. Subsequently, we propose to couple the ensemble predictions with a novel measurement error correction approach, to fully characterize the impact of air pollution on adverse health and the shape of the exposure-response curves. The proposed novel paradigm will greatly improves communication of exposure uncertainty in the health effect estimates both to policy makers and the public and can easily be extended for use at different locations and at a global scale, as well as for other environmental exposures.
During the coming year we will also complete work on Objective 4 of the project, which is to use the spatial scale-specific (regional, sub-regional, and local) temporal variability in PM2.5 mass that we developed in Objective 1 (Antonelli et al. 2017) to identify source types (regional, urban background, or local) and the composition of their emissions driving pollution-induced mortality in Eastern Massachusetts.
Project 3: Causal Estimates of Effects of Regional and National Pollution Mixtures on Health: Providing Tools for Policy Makers
Future plans include updating our BC, PM2.5, and ozone models, adding a NO2 model, and starting models for PM2.5 components nationwide. Simultaneously we plan to expand our outcomes to include the effects of long term exposure on hospital admissions, and to expand our causal modeling efforts for both acute and chronic exposures.
Project 4: A Causal Inference Framework to Support Policy Decisions by Evaluating the Effectiveness of Past Air Pollution Control Strategies for the Entire United States
We will continue to refine methodology for reduced-form models to produce spatially and temporally refined source-receptor mappings, including a dispersion implementation of HYSPLIT and investigation of other products produced by other ACE Centers (e.g., the EASIUR model from CMU). With a newly-hired postdoctoral fellow specializing in environmental engineering, we plan to formalize our comparison of different source-receptor mapping techniques for the specific purposes of evaluating interventions, as well as deploy these methods in a variety of health-outcome studies of interventions.
Project 5: Projecting and Quantifying Future Changes in Socioeconomic Drivers of Air Pollution and its Health-Related Impacts
With the integrated methodology now complete, the first major objective of this reporting period is to complete a comprehensive set of climate simulations (Objectives 1 and 5). Once generated, these will be applied in the newly-configured global chemistry-transport model GCHP, to provide fully transient estimates of ozone and PM2.5 impacts in the US over the next 100 years under different climate scenarios (Objectives 4 and 5). A central focus of year 3 will be to establish an analytical method through which the time of emergence of air quality impacts can be established. This will take advantage of our ensemble approach, with a separate evaluation for each climate scenario based on differences between climate change-driven change and local variability from 1980-2100. The new approach will provide a robust estimate of how and when we expect to be able to observe impacts of climate change on air quality, from state-level to regional and international analysis (Objective 5). On the economic analysis aspects of the project, we will continue work on USREP and expect to complete a study on the economic and air pollution effects of regional energy policies such as the Renewable Portfolio Standards (Objectives 2 and 3). We anticipate no significant additional timeline adjustments for the project.
Journal Articles: 419 Displayed | Download in RIS Format
| Other center views: | All 453 publications | 420 publications in selected types | All 419 journal articles |
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Abu Awad Y, Koutrakis P, Coull BA, Schwartz J. A spatio-temporal prediction model based on support vector machine regression: ambient black carbon in three New England states. Environmental Research 2017;159:427-434. |
R835872 (2016) |
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Achilleos S, Kioumourtzoglou M-A, Wu C-D, Schwartz JD, Koutrakis P, Papatheodorou SI. Acute effects of fine particulate matter constituents on mortality: a systematic review and meta-regression analysis. Environment International 2017;109:89-100. |
R835872 (2016) R835872C001 (Final) R835872C003 (Final) R834798 (Final) |
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Alahmad B, Khraishah H, Shakarchi A, Albaghdadi M, Koutrakis P, Petros J, Farouc A. Cardiovascular Mortality and Exposure to Heat in an Inherently Hot Region Implications for Climate Change. AHA Journals 2020;141(15):1271-1273 AB-. |
R835872 (2020) R835872C003 (Final) |
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Alahmad B, Shakarchi A, Khraishah H, Alseadidan M, Gasana J, Al-Hemoud A, Koutrakis P, Fox M. Extreme temperatures and mortality in Kuwait: who is vulnerable?. Science of the Total Environment 2020;732(139289). |
R835872 (2020) R835872C003 (Final) |
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Alahmad B, Vicedo-Cabrera A, Chen K, Garshick E, Bernstein A. Climate change and health in Kuwait:temperature and mortality projections under different climatic scenarios. ENVIRONMENTAL RESEARCH LETTERS 2022;17(7):074001. |
R835872 (2020) R835872C003 (Final) |
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Alahmad B, Khraishah H, Roye D, Vicedo-Cabrera AM, Guo YM, Papatheodorou SI, Achilleos S, Acquattoa F, Abrmstrong B, Bell ML. Associations Between Extreme Temperatures and Cardiovascular Cause-Specific Mortality:Results From 27 Countries. CIRCULATION 2022;147(1):35-46. |
R835872 (2021) |
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Alahmad B, Ali H, Alwadi Y, Al-Hemoud A, Koutrakis P, Al-Mulla F. Combined impact of heat and dust on diabetes hospitalization in Kuwait. BMJ OPEN DIABETES RESEARCH & CARE 2024;12(4):1-7 |
R835872 (Final) |
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Albers J, Ivan L, Clark B, Nacci D, Klinger R, Thrash A, Steibel J, Vinas N, Carvan M, Murphy C. Impacts on Atlantic Killifish from Neurotoxicants: Genes, Behavior, and Population-Relevant Outcomes. ENVIRONMENTAL SCIENCE & TECHNOLOGY 2024; |
R835872 (Final) R835798 (Final) |
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Alhamad B, AL-Hemoud A, Al-Bouwarthan M, Kharishah H, Kamel M, Akrouf Q, Wegman D, Bernstein A, Koutrakis P. Extreme heat and work injuries in Kuwait's hot summers. OCCUPATIONAL AND ENVIRONMENTAL MEDICINE 2023;80(6):347-352. |
R835872 (2021) |
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Anand K, Vieira C, Garshick E, Wang V, Bomberg A, Gold D, Schwartz J, Vokonas P, Koutrakis P. Solar and geomagnetic activity reduces pulmonary function and enhances particulate pollution effects. SCIENCE OF THE TOTAL ENVIRONMENT 2022;838(3):156434. |
R835872 (2021) R835872C001 (Final) R835872C003 (Final) |
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Antonelli J, Zigler C, Dominici F. Guided Bayesian imputation to adjust for confounding when combining heterogeneous data sources in comparative effectiveness research. Biostatistics 2017;18(3):553-568. |
R835872 (2016) |
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Antonelli J, Schwartz J, Kloog I, Coull BA. Spatial multiresolution analysis of the effect of PM2.5 on birth weights. The Annals of Applied Statistics 2017:11(2);792-807. |
R835872 (2017) R835872C002 (2016) R835872C002 (Final) R834798 (Final) |
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Antonelli J, Papadogeorgou G, Dominici F. Causal inference in high dimensions:A marriage between Bayesian modeling and good frequentist properties. BIOMETRICS 2022;78(1):100-114. |
R835872 (2020) R836156 (Final) |
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Awad YA, Di Q, Wang Y, Choirat C, Coull BA, Zanobetti A, Schwartz J. Change in PM2.5 exposure and mortality among Medicare recipients:combining a semi-randomized approach and inverse probability weights in a low exposure population. Environmental Epidemiology 2019;3(4):e054. |
R835872 (2019) R835872C003 (Final) |
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Bhaskar A, Chandra J, Hashemi H, Butler K, Bennett L, Cellini J, Braun D, Dominici F. A Literature Review of the Effects of Air Pollution on COVID-19 Health Outcomes Worldwide: Statistical Challenges and Data Visualization. ANNUAL REVIEW OF PUBLIC HEALTH 2023;44:1-20 |
R835872 (2021) |
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Blomberg A, Nyhan M, Bind M, Vokonas P, Coull B, Schwartz J, Koutrakis P. The role of ambient particle radioactivity in inflammation and endothelial function in an elderly cohort. Epidemiology 2020;31(4):499-508. |
R835872 (2020) R835872C001 (Final) R835872C002 (Final) R835872C003 (Final) |
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Blomberg A, Li L, Schwartz J, Coull B, Koutrakis P. Exposure to particle beta radiation in greater Massachusetts and factors influencing its spatial and temporal variability. Environmental Science & Technology 2020;54(11):6575-6583. |
R835872 (2020) R835872C001 (Final) R835872C002 (Final) R835872C003 (Final) |
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Bobb JF, Ho KKL, Yeh RW, Harrington L, Zai A, Liao KP, Dominici F. Time-Course of Cause-Specific Hospital Admissions During Snowstorms: An Analysis of Electronic Medical Records From Major Hospitals in Boston, Massachusetts. American Journal of Epidemiology 2017;185(4):283-294. |
R835872 (2016) R835872C005 (2016) |
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Bozigar M, Konstantinoudis G, Vieira C, Li L, Alwadi Y, Jones R, Koutrakis P. Domestic radon exposure and childhood cancer risk by site and sex in 727 counties in the United States, 2001-2018. SCIENCE OF THE TOTAL ENVIRONMENT 2024;954 |
R835872 (Final) |
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Braun D, Gorfine M, Parmigiani G, Arvold ND, Dominici F, Zigler C.Propensity scores with misclassified treatment assignment: a likelihood-based adjustment.Biostatistics2017;18(4):695-710. |
R835872 (2016) R835872C004 (2016) |
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Brunst KJ, Sanchez-Guerra M, Chiu YH, Wilson A, Coull BA, Kloog I, Schwartz J, Brennan KJ, Enlow MB, Wright RO, Baccarelli AA. Prenatal particulate matter exposure and mitochondrial dysfunction at the maternal-fetal interface:effect modification by maternal lifetime trauma and child sex. Environment international 2018;112:49-58. |
R835872 (2017) |
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Burnor E, Cserbik D, Cotter D, Palmer C, Ahmad H, Eckel S, Berhane K, McConnell R, Chen J, Schwartz J, Jackson R, Hertling M. Association of Outdoor Ambient Fine Particulate Matter With Intracellular White Matter Microstructural Properties Among Children. JAMA NETWORK OPEN 2021;4(12). |
R835872 (2020) R835441 (Final) |
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Busenkell E, Collins C, Moy M, Hart J, Grady S, Coull B, Schwartz J, Koutrakis P, Harshick E. Modification of associations between indoor particulate matter and systemic inflammation in individuals with COPD. ENVIRONMENT RESEARCH 2022;209(112802). |
R835872 (2020) R835872C002 (Final) R835872C003 (Final) R834798 (Final) |
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Carrion-Matta A, Kang C, Gaffin J, Hauptmat M, Phipatankakul W, Koutrakis P, Gold D. Classroom indoor PM2.5 sources and exposures in inner-city schools. ENVIRONMENT INTERNATIONAL 2019;131. |
R835872 (2020) R835872C001 (Final) |
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Carrion-Matta A, Lawrence J, Kang C, Wolfson J, Li L, Vieira C, Schwartz J, Demokritou P, Koutrakis P. Predictors of indoor radon levels in the Midwest United States. Journal of the Air & Waste Management Association 2021;71(12):1515-1528. |
R835872 (2020) R835872C001 (Final) |
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Carter S, Rahman M, Lin J, Shu Y, Chow T, Martinez M, Eckel S, Chen J, Chen Z, Schwartz J, Pavlovic N, Lurmann F, McConnell R, Ziang A. In utero exposure to near-roadway air pollution and autism spectrum disorder in children. ENVIRONMENTAL INTERNATIONAL 2022;158(106898). |
R835872 (2020) R835872C003 (Final) |
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Carter S, Rahman M, Lin J, Chow T, Yu X, Martinez M, Levitt P, Chen S, Chen J, Eckel S, Schwartz J, Lurmann F, Kleeman M, McConnell R, Xiang A. Maternal exposure to aircraft emitted ultrafine particles during pregnancy and likelihood of ASD in children. ENVIRONMENT INTERNATIONAL 2023;178(108061) |
R835872 (Final) |
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Casey J, Su J, Henneman L, Zigler C, Neophytou A, Catalano R, Gondalia R, Chen Y, Kaye L, Moyer S, Combs V, Simrall G, Smith T, Sublett J, Barrett M. Coal-fired power plant closures and retrofits reduce asthma morbidity in the local population. NATURE ENERGY 2020;5(5):365-366. |
R835872 (2020) |
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Casey J, Su J, Henneman L, Zigler C, Neophytou A, Catalano R, Gondalia R, Chen Y, Kaye L, Moyer S, Combs V, Simrall G, Smith T, Sublett J, Barrett M. Improved asthma outcomes observed in the vicinity of coal power plant retirement, retrofit and conversion to natural gas. NATURE ENERGY 2020;5(5):398. |
R835872 (2020) R835872C004 (Final) |
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Castillo M, Wagner J, Casuccio G, West R, Freedman F, Eisl H, Wang Z, Yip J, Kinney P. Field testing a low-cost passive aerosol sampler for long-term measurement of ambient PM2.5 concentrations and particle composition. ATMOSPHERIC ENVIRONMENT 2019;216:116905. |
R835872 (2020) R834798 (Final) |
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Castro E, Healy J, Liu A, Wei Y, Kosheleva A, Schwartz J. Interactive effects between extreme temperatures and PM2.5 on cause-specific mortality in thirteen US states. ENVIORNMENTAL RESEARCH LETTERS 2025;20(1):014011 |
R835872 (Final) |
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Catalano S, Moyer J, Weaver A, Di Q, Schwartz J, Catalano M, War-Caviness C. Associations between long-term fine particulate matter exposure and hospital procedures in heart failure patients. PLOS ONE 2023;18(5) |
R835872 (Final) |
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Cefalu M, Dominici F, Arvold N, Parmigiani G. Model averaged double robust estimation. Biometrics 2017;73(2):410-421. |
R835872 (2016) R834798 (Final) |
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Chambliss S, Matsui E, Zarate R, Zigler C. The Role of Neighborhood Air Pollution in Disparate Racial and Ethnic Asthma Acute Care Use. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 2024;210(2):178-185 |
R835872 (Final) |
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Chen K, Algan M, Purcell A, Nurhussien L, Koutrakis P, Coull B, Synn A, Rice M. Physical Activity, Air Pollution Exposure, and Lung Function Interactions Among Adults with COPD. CHRONIC OBSTRUCTIVE PULMONARY DISEASES - JOURNAL OF THE COPD FOUNDATION 2023;10(2):170-177 |
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Chen YH, Mukherjee B, Adar SD, Berrocal VJ, Coull BA. Robust distributed lag models using data adaptive shrinkage. Biostatistics 2017;19(4):461-478. |
R835872 (2017) R835872 (2018) R835872C002 (Final) |
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Chossiere G, Xu H, Dixit Y, Isaacs S, Eastham S, Allroggen F, Speth R, Barrett S. Air pollution impacts of COVID-19-related containment measures. SCIENCE ADVANCES 2021;7(21):eabe1178. |
R835872 (2020) R835872C005 (Final) |
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Chu M, Gillooly S, Levy J, Vallarino J, Reyna L, Laurent J, Coull B, Adamkiewicz G. Real-time indoor PM2.5 monitoring in an urban cohort:Implications for exposure disparities and source control. ENVIRONMENTAL RESEARCH 2021;193(110561). |
R835872 (2020) R836156 (Final) |
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Colicino E, Wilson A, Frisardi MC, Prada D, Power MC, Hoxha M, Dioni L, Spiro III A, Vokonas PS, Weisskopf MG, Schwartz JD, Baccarelli AA. Telomere length, long-term black carbon exposure, and cognitive function in a cohort of older men:the VA Normative Aging Study. Environmental Health Perspectives 2017;125(1):76-81. |
R835872 (2016) R835872C003 (Final) R832416 (Final) R834798 (Final) |
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Dai L, Mehta A, Mordukhovich I, Just AC, Shen J, Hou L, Koutrakis P, Sparrow D, Vokonas PS, Baccarelli AA, Schwartz JD. Differential DNA methylation and PM2.5 species in a 450K epigenome-wide association study. Epigenetics 2017;12(2):139-148. |
R835872 (2016) R835872 (2017) |
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Daouda M, Henneman L, Kioumourtzoglou M, Gemmill A, Zigler C, Casey J. Association between county-level coal-fired power plant pollution and racial disparities in preterm births from 2000 to 2018. ENVIRONMENTAL RESEARCH LETTERS 2021;16(3):34055. |
R835872 (2020) |
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Deslauriers J, Redlich C, Kang C, Grady S, Slade M, Koutrakis P, Garshick E. Determinants of indoor carbonaceous aerosols in homes in the Northeast United States. JOURNAL OF THE EXPOSURE SCIENCE & ENVIRONMENTAL EPIDEMIOLOGY 2022;. |
R835872 (2020) R835872C001 (Final) R834798 (Final) |
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Di Q, Dai L, Wang Y, Zanobetti A, Choirat C, Schwartz JD, Dominici F. Association of short-term exposure to air pollution with mortality in older adults. JAMA 2017;318(24):2446-2456. |
R835872 (2016) R835872 (2017) R834798 (Final) |
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Di Q, Rowland S, Koutrakis P, Schwartz J. A hybrid model for spatially and temporally resolved ozone exposures in the continental United States. Journal of the Air & Waste Management Association 2017;67(1):39-52. |
R835872 (2016) R834798 (Final) |
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Di Q, Wang Y, Zanobetti A, Wang Y, Koutrakis P, Choirat C, Dominici F, Schwartz JD. Air pollution and mortality in the Medicare population. New England Journal of Medicine 2017;376(26):2513-2522. |
R835872 (2016) R835872 (2017) R835872C003 (Final) R835872C004 (Final) R834798 (Final) R834798C002 (Final) |
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Dominici F, Zigler C. Best practices for gauging evidence of causality in air pollution epidemiology. American Journal of Epidemiology 2017;186(12):1303-1309. |
R835872 (2016) |
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Dong S, Abu-Awad Y, Kosheleva A, Fong K, Koutrakis P, Schwartz J. Maternal exposure to black carbon and nitrogen dioxide during pregnancy and birth weight:Using machine-learning methods to achieve balance in inverse-probability weights. ENVIRONMENTAL RESEARCH 2022;211(112987). |
R835872 (2020) R835872C003 (Final) |
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Dong S, Koutrakis P, Li L, Coull B, Schwartz J, Kosheleva A, Zanobetti A. Synergistic effects of particle radioactivity (gross beta activity) and particulate matter =< 2.5 mu m aerodynamic diameter on cardiovascular disease mortality. Journal of the American Heart Association 2022;11(20):e025470. |
R835872 (2021) R835872C001 (Final) R835872C003 (Final) |
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Dorans KS, Wilker EH, Li W, Rice MB, Ljungman PL, Schwartz J, Coull BA, Kloog I, Koutrakis P, D’Agostino RB, Massaro JM, Hoffmann U, O'Donnell J, Mittleman MA. Residential proximity to major roads, exposure to fine particulate matter, and coronary artery calcium: the Framingham Heart Study. Arteriosclerosis, Thrombosis, and Vascular Biology 2016;36(8):1679-1685. |
R835872 (2016) R835872C003 (Final) R834798 (Final) |
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dos Santos N, Zilli V, Nascimento S, Mazzilli B, Saki M, Saueia C, Saldiva De Andre C, Justo L, Tisti M, Koutrakis P. Levels of Polonium-210 in brain and pulmonary tissues:Preliminary study in autopsies conducted in the city of Sao Paulo, Brazil. SCIENTIFIC REPORTS 2020;10(1):180. |
R835872 (2020) R835872C001 (Final) R835872C003 (Final) R834798 (Final) |
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Dovrou E, Bates K, MOch J, Mickley L, Jacob D, Keutsch F. Catalytic role of formaldehyde in particulate matter formation. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES 2022;119(6):e2113265119. |
R835872 (2020) R835872C001 (Final) |
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Fiffer M, Kang C, Requia W, Koutrakis P. Long-term impact of PM(2.5)mass and sulfur Reductions on ultrafine particle trends in Boston, MA from 1999 to 2018. JOURNAL OF THE AIR & WASTE MANAGEMENT ASSOCIATION 2020;70(7):700-707. |
R835872 (2020) R835872C001 (Final) R834798 (Final) |
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Fong KC, Hart JE, James P. A review of epidemiologic studies on greenness and health:updated literature through 2017. Current Environmental Health Reports 2018;5(1):77-87. |
R835872C003 (Final) R836156 (2018) R836156 (2019) R836156 (2020) |
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Fong KC, Kosheleva A, Kloog I, Koutrakis P, Laden F, Coull BA, Schwartz JD. Fine particulate air pollution and birthweight:differences in associations along the birthweight distribution. Epidemiology 2019;30(5):617-623. |
R835872 (2019) R835872C002 (Final) R835872C003 (Final) |
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Gaskins A, Tang Z, Hood R, Ford J, Schwartz J, Jones D, Laden F, Liang D. Periconception air pollution, metabolomic biomarkers, and fertility among women undergoing assisted reproduction. ENVIRONMENTAL INTERNATIONAL 2021;155:106666. |
R835872 (2020) R835872C003 (Final) R834798 (Final) |
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Grady ST, Koutrakis P, Hart JE, Coull BA, Schwartz J, Laden F, Zhang JJ, Gong J, Moy ML, Garshick E. Indoor black carbon of outdoor origin and oxidative stress biomarkers in patients with chronic obstructive pulmonary disease. Environment International 2018;115:188-195. |
R835872 (2018) R835872C001 (Final) R835872C003 (Final) R834798 (Final) |
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Hao H, Wang Y, Zhu Q, Zhang H, Rosenberg A, Schwartz J, Amini H, van Donkelaar A, Martin R, Liu P, Weber R, Russel A, Yitshak-sade M, Chang H, Shi L. National Cohort Study of Long-Term Exposure to PM2.5 Components and Mortality in Medicare American Older Adults. ENVIRONMENTAL SCIENCE & TECHNOLOGY 2023;57(17):6835-6843. |
R835872 (2021) |
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Hart JE, Grady ST, Laden F, Coull BA, Koutrakis P, Schwartz JD, Moy ML, Garshick E. Effects of indoor and ambient black carbon and PM 2.5 on pulmonary function among individuals with COPD. Environmental Health Perspectives 2018;126(12):127008. |
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Healy J, Yazdi M, Wei Y, Qiu X, Shtein A, Dominici F, Shi L, Schwartz J. Seasonal Temperature Variability and Mortality in the Medicare Population. ENVIRONMENT HEALTH PERSPECTIVES 2023;131(7) |
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Henneman L, Shen H, Hogrefe C, Russell A, Zigler C. Four Decades of Mobile Source Pollutants:Spatial-Temporal Trends Assessed by Ground-Based Monitors, Air Quality Models, and Satellites. ENVIRONMENTAL SCIENCE & TECHNOLOGY 2021;55(2):882-892. |
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Henneman L, Rasel M, Choirat C, Anenberg S, Zigler C. Inequitable Exposures to US Coal Power Plant-Related PM2.5: 22 Years and Counting. ENVIRONMENTAL HEALTH PERSPECTIVES 2023;131(3):037005 |
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Heo S, Li L, Son J, Koutrakis P, Bell M. Associations Between Gestational Residential Radon Exposure and Term Low Birthweight in Connecticut, USA. EPIDEMIOLOGY 2024;35(6):834-843 |
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Hood R, James P, Fong K, Minguez-Alcaron L, Coull B, Schwartz J, Kloog I, Laden F, Gasking A. The influence of fine particulate matter on the association between residential greenness and ovarian reserve. ENVIRONMENTAL RESEARCH 2021;197:111162. |
R835872 (2020) R835872C002 (Final) R835872C003 (Final) R834798 (Final) |
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Huang S, Song S, Sielsen C, Zhang Y, Xiong J, Weschler L, Shaodong L. Residential building materials:An important source of ambient formaldehyde in mainland China. ENVIRONMENTAL INTERNATIONAL 2022;158(106909). |
R835872 (2020) |
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Huang Y, Kioumourtzoglou M, Mittleman M, Ross Z, Williams M, Friedman A, Schwartz J, Wapter R, Anath C. Air Pollution and Risk of Placental Abruption:A Study of Births in New York City, 2008-2014. AMERICAN JOURNAL OF EPIDEMIOLOGY 2021;190(6):1021-1033. |
R835872 (2020) |
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Hwang S, Hood R, Hauser R, Schwartz J, Laden F, Jones D, Liang D, Gaskins A. Using follicular fluid metabolomics to investigate the association between air pollution and oocyte quality. ENVIRONMENTAL INTERNATIONAL 2022;169(107522). |
R835872 (2021) R834798 (Final) |
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Jbally A, Zhou X, Liu J, Lee T, Kamareddine L, Verguet S, Dominici F. Air pollution exposure disparities across population and income groups. NATURE 2022;601(7892):228-233. |
R835872 (2020) |
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Jin T, Amini H, Kosheleva A, Yazdi M, Wei T, Castro E, Di Q, Shi L, Schwartz J. Associations between long-term exposures to airborne PM2.5 components and mortality in Massachusetts:mixture analysis exploration. ENVIRONMENTAL HEALTH 2022;21(1):96. |
R835872 (2021) R835872C003 (Final) |
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Kelp M, Lin S, Kutz J, Mickley L. A new approach for determining optimal placement of PM2.5 air quality sensors:case study for the contiguous United States. ENVIRONMENTAL RESEARCH LETTERS 2022;17(3). |
R835872 (2020) R835872C001 (Final) |
Exit Exit |
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Kelp M, Fargiano T, Lin S, Liu T, Turner J, Kutz J, Mickley L. Data-Driven Placement of PM2.5 Air Quality Sensors in the United States: An Approach to Target Urban Environmental Injustice. GEOHEALTH 2023;7(9):e2023GH000834 |
R835872 (Final) |
Exit |
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Key T, Tyagi P, Sabath M, Karareddine L, Henneman L, Braun D, Dominici F. Counterfactual time series analysis of short-term change in air pollution following the COVID-19 state of emergency in the United States. SCIENTIFIC REPORTS 2021;11(1):23517. |
R835872 (2020) |
Exit Exit |
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Kim C, Tec M, Zigler C. Bayesian nonparametric adjustment of confounding. BIOMETRICS 2023;Early Access |
R835872 (2021) R835872C004 (Final) |
Exit |
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Kingsley SL, Eliot MN, Glazer K, Awad YA, Schwartz JD, Savitz DA, Kelsey KT, Marsit CJ, Wellenius GA. Maternal ambient air pollution, preterm birth and markers of fetal growth in Rhode Island:results of a hospital-based linkage study. Journal of Epidemiology and Community Health 2017;71(12):1131-1136. |
R835872 (2017) R834798 (Final) |
Exit |
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Kodros J, Bell M, Dominici F, L'Orange C, Pollitt K, Weichenthal S, Wu X, Volkens J. Unequal airborne exposure to toxic metals associated with race, ethnicity, and segregation in the USA. NATURE COMMUNICATIONS 2022;13(1):6329. |
R835872 (2021) |
Exit |
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Lee KH, Tadesse MG, Baccarelli AA, Schwartz J, Coull BA. Multivariate Bayesian variable selection exploiting dependence structure among outcomes:application to air pollution effects on DNA methylation. Biometrics 2017;73(1):232-241. |
R835872 (2017) R835872C002 (Final) |
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Lee M, Schwartz J, Wang Y, Dominici F, Zanobetti A. Long-term effect of fine particulate matter on hospitalization with dementia. Environmental Pollution 2019;254:112. |
R835872 (2019) R835872C003 (Final) R835872C004 (Final) R834798 (Final) |
Exit Exit |
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Lee M, Eum K, Li L, Iafrate J, Lanuti M, Koutrakis P, Christiani D. Ambient beta particle radioactivity and lung cancer survival: Results from the Boston Lung Cancer Study. ENVIRONMENTAL RESEARCH 2025;264 |
R835872 (Final) |
Exit |
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Leung M, Rowland S, Coull B, Modest A, Hacker M, Schwartz J, Kioumourtzoglou M, Weisskopf M, Wilson A. Bias Amplification and Variance Inflation in Distributed Lag Models Using Low-Spatial-Resolution Data. AMERICAN JOURNAL OF EPIDEMIOLOGY 2023;Online ahead of print |
R835872 (2021) |
Exit |
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Leung M, Modest A, Hacker M, Wylie B, Wei Y, Schwartz J, Iyer H, Hart J, Coull B, Laden F, Weisskopf M, Papatheodorou S. Traffic-Related Air Pollution and Ultrasound Parameters of Fetal Growth in Eastern Massachusetts. AMERICAN JOURNAL OF EPIDEMIOLOGY 2023;Epub ahead of print |
R835872 (Final) |
Exit |
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Leung M, Weisskopf M, Modest A, Hacker M, Iyer H, Hart J, Wei Y, Schwartz J, Coull B, Laden F, Papatheodorou S. Using Parametric g-Computation for Time-to-Event Data and Distributed Lag Models to Identify Critical Exposure Windows for Preterm Birth: An Illustrative Example Using PM 2,5 in a Retrospective Birth Cohort Based in Eastern Massachusetts (2011-2016). ENVIRONMENTAL HEALTH PERSPECTIVES 2024;132(7) |
R835872 (Final) |
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Li J, Garschick E, Al-Hemud A, Huang S, Koutrakis P. Impacts of meteorology and vegetation on surface dust concentrations in Middle Eastern countries. SCIENCE OF THE TOTAL ENVIRONMENT 2020;712(136597). |
R835872 (2020) R835872C001 (Final) |
Exit Exit |
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Li J, Garshick E, Hart J, Li L, Si L, Al-Hemoud A, Huang S, Koutrakis P. Estimation of ambient PM2.5 in Iraq and Kuwait from 2001 to 2018 using machine learning andRemote sensing. ENVIRONMENT INTERNATIONAL 2021;151(106445). |
R835872 (2020) |
Exit Exit |
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Li J, Garshick E, Huang S, Koutrakis P. Impacts of El Nino-Southern Oscillation on surface dust levels across the world during 1982-2019. Sci Total Environ 2021; 769:144566 |
R835872C001 (Final) |
Exit Exit |
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Li L, Blomberg A, Spengler J, Coull B, Schwartz J, Koutrakis P. Unconventional oil and gas development and ambient particle radioactivity. NATURE COMMUNICATIONS 2020;11(1):5002. |
R835872 (2020) R835872C002 (Final) |
Exit Exit |
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Li L, Dominici F, Blomberg A, Bargagli-Stoffi F, Schwartz J, Coull B, Spengler J, Wei Y, Lawrence J, Koutrakis P. Exposure to unconventional oil and gas development and all-cause mortality in Medicare beneficiaries. NATURE ENERGY 2021;7(2):177-185. |
R835872 (2020) R835872C001 (Final) R835872C003 (Final) |
Exit Exit |
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Li L, Stern R, Blomberg A, Kang C, Wei Y, Liu M, Peralta A, Lawrence J, Vieira C, Koutrakis P. Ratios between radon concentrations in upstairs and basements: a study in the Northeastern and Midwestern United States. Data Science 2022;9(2):191-197. |
R835872 (2020) R835872C001 (Final) |
Exit Exit |
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Li L, Coull B, Koutrakis P. A national comparison between the collocated short- and long-term radon measurements in the United States. JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY 2023;Epub ahead of print |
R835872 (2021) |
Exit |
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Li L, Coull B, Vieira C, Koutrakis P. High- resolution national radon maps based on massive indoor measurements in the United States. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2025;122(3) |
R835872 (Final) |
Exit |
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Li W, Dorans KS, Wilker EH, Rice MB, Long MT, Schwartz J, Coull BA, Koutrakis P, Gold DR, Fox CS, Mittleman MA. Residential proximity to major roadways, fine particulate matter, and hepatic steatosis: the Framingham Heart Study. American Journal of Epidemiology 2017;186(7):857-865. |
R835872 (2016) R835872C003 (Final) R834798 (Final) R834798C004 (Final) |
Exit |
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Li W, Dorans KS, Wilker EH, Rice MB, Ljungman PL, Schwartz JD, Coull BA, Koutrakis P, Gold DR, Keaney Jr JF, Vasan RS, Benjamin EJ, Mittleman MA. Short-term exposure to ambient air pollution and biomarkers of systemic inflammation: the Framingham Heart Study. Arteriosclerosis, Thrombosis, and Vascular Biology 2017;37(9):1793-1800. |
R835872 (2016) R834798 (Final) |
Exit Exit Exit |
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Li W, Dorans KS, Wilker EH, Rice MB, Kloog I, Schwartz JD, Koutrakis P, Coull BA, Gold DR, Meigs JB, Fox CS, Mittleman MA. Ambient air pollution, adipokines, and glucose homeostasis: the Framingham Heart Study. Environment International 2018;111:14-22. |
R835872 (2016) R835872C002 (Final) R835872C003 (Final) |
Exit Exit Exit |
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Li W, Nyhan MM, Wilker EH, Vieira CL, Lin H, Schwartz JD, Gold DR, Coull BA, Aba AM, Benjamin EJ, Vasan RS. Recent exposure to particle radioactivity and biomarkers of oxidative stress and inflammation:the Framingham Heart Study. Environment International 2018;121:1210-1216. |
R835872 (2019) R835872C001 (Final) R835872C002 (Final) R835872C003 (Final) |
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Liang D, Lee W, Liao J, Lawence J, Wolfson J, Ebelt S, Kang C, Koutrakis P, Samat J. Estimating climate change-related impacts on outdoor air pollution infiltration. ENVIRONMENTAL RESEARCH 2021;196(110923). |
R835872 (2020) R835872C001 (Final) R834798 (Final) R835755 (Final) |
Exit Exit |
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Liu M, Kang C, Wolfson J, Mikhail L, Coull B, Schwartz J, Koutrakis P. Measurements of gross alpha-and beta-activities of archived PM2.5 and PM10 teflon filter samples. Environmental Science & Technology 2020;54(19):11780-11788. |
R835872 (2020) R835872C001 (Final) R835872C002 (Final) |
Exit Exit |
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Liu R, Wei Y, Qiu X, Kosheleva A, Schwartz J. Short term exposure to air pollution and mortality in the US:a double negative control analysis. ENVIRONMENTAL HEALTH 2022;21(1):81. |
R835872 (2021) |
Exit |
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Liu S, Bobb J, ClaHenn B, Schnaas L, Tellez-Rojo M, Gennings C, Aurora M, Wright R, Coull B, Want M. Modeling the health effects of time-varying complex environmental mixtures:Mean field variational Bayes for lagged kernel machine regression. ENVIRONMETRICS 2018;29(4):e2504. |
R835872 (2020) |
Exit Exit |
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Lugilo D, Kleeman M, Yu X, Lin J, Chow T, Martinez M, Chen S, Chen J, Eckel S, Schwartz J, Lurmann F, McConnel R, Xiang A, Rahman M. Prenatal Exposure to Source-Specific Fine Particulate Matter and Autism Spectrum Disorder. ENVIRONMENTAL SCIENCE & TECHNOLOGY 2024;. |
R835872 (Final) |
Exit |
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MacNaughton P, Eitland E, Kloog I, Schwartz J, Allen J. Impact of particular matter exposure and surrounding “greenness” on chronic absenteeism in Massachusetts public schools. International Journal of Environmental Research and Public Health 2017;14(2):E207. |
R835872 (2016) R835872C003 (Final) R834798 (Final) |
Exit |
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MacNaughton P, Eitland E, Kloog I, Schwartz J, Allen J. Impact of Particulate Matter Exposure and Surrounding Greenness on Chronic Absenteeism in Massachusetts Public Schools. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH 2017;14(2):207. |
R835872 (2020) R834798 (Final) |
Exit Exit |
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Mahmodi G, Bafti R, Boroujeni N, Pradhan S, Danwal S, Sengupta B, Vatanpour V, Sorci M, Fathizadeh M, Bikkina P, Belfort G, Yu M, Kim S. Improving cellulose acetate mixed matrix membranes by incorporating hydrophilic MIL-101(Cr)-NH2 nanoparticles for treating dye/salt solution. CHEMICAL ENGINEERING JOURNAL 2023;477(146736) |
R835872 (Final) R835441 (Final) SU840147 (Final) |
Exit |
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Makar M, Antonelli J, Di Q, Cutler D, Schwartz J, Dominici F. Estimating the causal effect of low levels of fine particulate matter on hospitalization. Epidemiology 2017;28(5):627-634. |
R835872 (2016) R835872 (2017) R835872C003 (Final) R835872C004 (Final) R835872C005 (2016) |
Exit Exit |
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Marlier M, Brenner K, Liu J, Mickley L, Raby S, James E, Ahmadov R, Riden H. Exposure of agricultural workers in California to wildfire smoke under past and future climate conditions. ENVIRONMENTAL RESEARCH LETTERS 2022;17(9):094045. |
R835872 (2021) R835872C001 (Final) |
Exit Exit |
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Martins M, Lawrence J, Ferguson S, Wolfson JM, Koutrakis P. Development and evaluation of a mobile laboratory for collecting short-duration near-road fine and coarse ambient particle and road dust samples. J Air Waste Manag Assoc 2021; 71(2):118-128. |
R835872C001 (Final) |
Exit Exit |
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Masri S, Garshick E, Hart J, Bouhamra W, Koutrakis P. Use of visual range measurements to predict fine particulate matter exposures in Southwest Asia and Afghanistan. Journal of the Air & Waste Management Association 2017;67(1):75-85. |
R835872 (2016) R835872C001 (Final) R834798 (Final) |
Exit Exit Exit |
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Masri S, Garshick E, Coull B, Koutrakis P. A novel calibration approach using satellite and visibility observations to estimate fine particulate matter exposures in Southwest Asia and Afghanistan. Journal of the Air & Waste Management Association 2017;67(1):86-95. |
R835872 (2016) R835872C001 (Final) R834798 (Final) |
Exit Exit Exit |
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Matthaios V, Liu M, Li L, Kang M, Vieira C, Gold D, Koutrakis P. Sources of indoor PM2.5 gross alpha and beta activities measured in 340 homes. ENVIRONMENTAL RESEARCH 2021;197. |
R835872 (2020) R835872C001 (Final) R834798 (Final) |
Exit Exit |
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Matthaios V, Kang C, Wolfson J, Greco K, Gaffin J, Hauptman M, Cunningham A, Petty C, Lawrence J, Gold D, Koutrakis P. Factors Influencing Classroom Exposures to Fine Particles, Black Carbon, and Nitrogen Dioxide in Inner-City Schools and Their Implications for Indoor Air Quality. ENVIRONMETAL HEALTH PERSPECTIVES 2022;130(4):47005. |
R835872 (2020) R835872C001 (Final) R834798 (Final) |
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Matthaios V, Lawrence J, Martins M, Ferguson S, Wolfson J, Harrison R, Kourtrakis P. Quantifying factors affecting contributions of Roadway exhaust and non-exhaust emissions to ambient PM10-2.5 and PM2.5-0.2 particles. SCIENCE OF THE TOTAL ENVRIONMENT 2022;835. |
R835872 (2020) R835872C001 (Final) R834677 (Final) |
Exit Exit |
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Matthaios V, Holland I, Kang C, Hart J, Hauptman M, Wolfson JM, Gaffin J, Phipatanakul W, Gold DR, Koutrakis P. The effects of urban green space and road proximity to indoor traffic-related PM2.5, NO2, and BC exposure in inner-city schools. JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIMDEMIOLOGY 2024; |
R835872 (Final) |
Exit |
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McGee G, Wilson A, Webster T, Coull B. Bayesian multiple index models for environmental mixtures. BIOMETRICS 2021;1(3). |
R835872 (2020) R839278 (2020) |
Exit Exit |
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McGuinn LA, Ward-Caviness C, Neas LM, Schneider A, Di Q, Chudnovsky A, Schwartz J, Koutrakis P, Russell AG, Garcia V, Kraus WE, Hauser ER, Cascio W, Diaz-Sanchez D, Devlin RB. Fine particulate matter and cardiovascular disease: comparison of assessment methods for long-term exposure. Environmental Research 2017;159:16-23. |
R835872 (2016) R834799 (Final) |
Exit Exit Exit |
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McGuinn LA, Windham GC, Kalkbrenner AE, Bradley C, Di Q, Croen LA, Fallin MD, Hoffman K, Ladd-Acosta C, Schwartz J, Rappold AG, Richardson DB, Neas LM, Gammon MD, Schieve LA, Daniels JL. Early Life Exposure to Air Pollution and Autism Spectrum Disorder:Findings from a Multisite Case-Control Study. Epidemiology 2020; 31(1):103-114. |
R835872C003 (Final) |
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Moch JM, Dovrou E, Mickley LJ, Keutsch FN, Liu Z, Wang Y, Dombek TL, Kuwata M, Budisulistiorini SH, Yang L, Decesari S, Paglione M, Alexander B, Shao J, Munger JW, Jacob DJ. Global importance of hydroxymethanesulfonate in ambient particulate matter: implications for air quality. J Geophys Res Atmos 2020; 125(18):e2020JD032706. |
R835872 (2020) R835872C001 (Final) |
Exit Exit |
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Nassan FL, Wang C, Kelly RS, Lasky-Su JA, Vokonas PS, Koutrakis P, Schwartz JD. Ambient PM2.5 species and ultrafine particle exposure and their differential metabolomic signatures. Environ Int 2021; 151:106447. |
R835872 (2020) R835872C003 (Final) |
Exit Exit |
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Nassan FL, Kelly RS, Kosheleva A, Koutrakis P, Vokonas PS, Lasky-Su JA, Schwartz JD. Metabolomic signatures of the long-term exposure to air pollution and temperature. Environ Health 2021; 20(1):3. |
R835872C003 (Final) |
Exit Exit |
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Nassan F, Kelly R, Koutrakis P, Vokonas P, Lasky-Su J, Schwartz J. Metabolomic signatures of the short-term exposure to air pollution and temperature. ENVIRONMENTAL RESEARCH 2021;201(111553). |
R835872 (2020) |
Exit Exit |
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Nurhussien L, Kang C, Koutrakis P, Coull B, Rice M. Air Pollution Exposure and Daily Lung Function in Chronic Obstructive Pulmonary Disease Effect Modification by Eosinophil Level. ANNALS OF THE AMERICAN THORACIC SOCIETY 2022;19(5):728-736 |
R835872 (2020) R835872C003 (Final) |
Exit |
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Nwanaji-Enwerem JC, Colicino E, Dai L, Di Q, Just AC, Hou L, Vokonas P, De Vivo I, Lemos B, Lu Q, Weisskopf MG, Baccarelli AA, Schwartz JD. miRNA processing gene polymorphisms, blood DNA methylation age and long-term ambient PM2.5 exposure in elderly men. Epigenomics 2017;9(12):1529-1542. |
R835872 (2016) R832416 (Final) |
Exit |
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Nwanaji-Enwerem JC, Bind M-A, Dai L, Oulhote Y, Colicino E, Di Q, Just AC, Hou L, Vokonas P, Coull BA, Weisskopf MG, Baccarelli AA, Schwartz JD. Editor’s highlight: Modifying role of endothelial function gene variants on the association of long-term PM2.5 exposure with blood DNA methylation age: the VA Normative Aging Study. Toxicological Sciences 2017;158(1):116-126. |
R835872 (2016) R832416 (Final) |
Exit Exit |
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Nwanaji-Enwerem JC, Colicino E, Dai L, Cayir A, Sanchez-Guerra M, Laue HE, Nguyen VT, Di Q, Just AC, Hou L, Vokonas P, Coull BA, Weisskopf MG, Baccarelli AA, Schwartz JD. Impacts of the mitochondrial genome on the relationship of long-term ambient fine particle exposure with blood DNA methylation age. Environmental Science & Technology 2017;51(14):8185-8195. |
R835872 (2016) R835872 (2017) R832416 (Final) |
Exit Exit Exit |
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Nyhan MM, Rice M, Blomberg A, Coull BA, Garshick E, Vokonas P, Schwartz J, Gold DR, Koutrakis P. Associations between ambient particle radioactivity and lung function. Environment International 2019;130:104795. |
R835872 (2019) R835872C001 (Final) R835872C003 (Final) |
Exit |
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Onyango S, North C, Ellaithy H, Tumwesigye P, Kang C, Matthaios V, Mukama M, Nambogo N, Wolfson J, Ferguson S, Asiimwe S, Atuyambe L, Santorino D, Christiani D, Koutrakis P. Ambient PM2.5 Temporal Variation and Source Apportionment in Mbarara, Uganda. AEROSOL AND AIR QUALITY RESEARCH 2024;24(4):230203. |
R835872 (Final) |
Exit |
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Overholtzer L, Ahmadi H, Bottenhornm K, Hsu E, Hertling M. Delay discounting and nucleus accumbens functional connectivity are related to weight status in adolescents from the ABCD study. PEDIATRIC OBESITY 2024; |
R835872 (Final) |
Exit |
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Papadogeorgou G, Dominici F. A causal exposure response function with local adjustment for confounding: Estimating health effects of exposure to low levels of ambient fine particulate matter. Annals of Applied Statistics 2020; 14(2):850-871. |
R835872 (2020) R835872C004 (Final) |
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Papatheodorou S, Yao W, Vieira C, Li L, Wylie B, Schwartz J, Koutrakis P. Residential radon exposure and hypertensive disorders of pregnancy in Massachusetts, USA: a cohort study. Environmental International 2021;146(106285). |
R835872 (2020) R835872C001 (Final) R835872C003 (Final) |
Exit Exit |
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Peralta A, Link M, Schwartz J, Luttmann-Gibson H, Dockery D, Blombarg A, Wei Y, Mittleman M, Gold D, Laden F, Coull B, Koutrakis P. Exposure to air pollution and particle radioactivity with the risk of ventricular arrhythmias. Circulation 2020;142(9):858-867. |
R835872 (2020) R835872C001 (Final) R835872C002 (Final) R835872C003 (Final) |
Exit Exit |
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Phipatanakul W, Koutrakis P, Coull BA, Kang CM, Wolfson JM, Ferguson ST, Petty CR, Samnaliev M, Cunningham A, Sheehan WJ, Gaffin JM, Baxi SN, Lai PS, Permaul P, Liang L, Thorne PS, Adamkiewicz G, Brennan KJ, Baccarelli AA, Gold DR. The school inner-city asthma intervention study: design, rationale, methods, and lessons learned. Contemporary Clinical Trials 2017;60:14-23. |
R835872 (2016) R834798 (Final) |
Exit Exit |
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Picciano P, Qiu M, Eastham S, Yuan M, Reilly J, Selin N. Air quality related equity implications of US decarbonization policy. NATURE COMMUNICATIONS 2023;14(1) |
R835872 (Final) R835872C005 (Final) |
Exit |
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Pienkosz B, Saari R, Monier E, Garcia-Menendez F. Natural Variability in Projections of Climate Change Impacts on Fine Particulate Matter Pollution. UNIVERSITY OF CALIFORNIA 2019;7(7):762-770. |
R835872 (2020) |
Exit |
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PLeung M, Laden F, Coull B, Modest A, Hacker M, Wylie B, Lyer H, Hart J, Wei Y, Schwartz J, Weisskopf M, Papatheodorou S. Ambient temperature during pregnancy and fetal growth in Eastern Massachusetts, USA. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY 2022; |
R835872 (2021) |
Exit |
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Qiu M, Zigler C, Selin N. Impacts of wind power on air quality, premature mortality, and exposure disparities in the United States. SCIENCE ADVANCES 2022;8(48):eabn8762 |
R835872 (2021) R835872C005 (Final) |
Exit |
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Qiu M, ZIgler C, Selin N. Statistical and machine learning methods for evaluating trends in air quality under changing meteorological conditions. ATMOSPHERIC CHEMISTRY AND PHYSICS 2022;22(16):10551-10566. |
R835872 (2021) R835872C004 (Final) R835872C005 (Final) |
Exit Exit |
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Qiu X, Danesh-Sazdi M, Wei Y, Di Q, Just A, Zanobetti A, Weisskopf M, Dominici F, Schwartz J. Associations of short-term exposure to air pollution and increased ambient temperature with psychiatric hospital admissions in older adults in the USA:a case-crossover study. LANCET PLANETARY HEALTH 2022;6(4):e331-e341. |
R835872 (2020) |
Exit Exit |
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Qiu X, Wei Y, Amini H, Wang C, Weisskopf M, Koutrakis P, Schwartz J. Fine particle components and risk of psychiatric hospitalization in the US. SCIENCE OF THE TOTAL ENVIRONMENT 2022;849(157934). |
R835872 (2021) |
Exit Exit |
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Qiu X, Shi L, Kubzansky L, Wei Y, Castro E, Li H, Weisskopf M, Schwartz J. Association of Long-term Exposure to Air Pollution With Late-Life Depression in Older Adults in the US. JAMA NETWORK OPEN 2023;6(2) |
R835872 (Final) |
Exit |
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Rahman M, Carter S, Lin J, Chow T, Yu X, Martinez M, Chen S, Chen J, Rud D, Lewinger J, van Donkelaar A, Martin R, Eckel S, Schwartz J, Lurmann F, Kleeman M, McConnell R, Xiang A. Associations of Autism Spectrum Disorder with PM2.5 Components: A Comparative Study Using Two Different Exposure Models. ENVIRONMENTAL SCIENCE & TECHNOLOGY 2022;57(1):405-414 |
R835872 (2021) |
Exit |
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Rahman M, Shu Y, Chow T, Lurmann F, Yu X, Martinez M, Carter S, Eckel S, Chen J, Chen Z, Levitt P, Schwartz J, McConnell R, Xiang A. Prenatal Exposure to Air Pollution and Autism Spectrum Disorder:Sensitive Windows of Exposure and Sex Differences. ENVIRONMENTAL HEALTH PERSPECTIVES 2022;130(1). |
R835872 (2020) R835872C003 (Final) |
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Rahman M, Carter S, Lin J, Chow T, Yu X, Martinez M, Mayra P, Levitt P, Checn Z, Chen J, Rud D, Lewinger J, Eckel S, Schwartz J, Lurmann F, Kleeman M, McConnell R, Xiang A. Prenatal exposure to tailpipe and non-tailpipe tracers of particulate matter pollution and autism spectrum disorders. ENVIRONMENT INTERNATIONAL 2023;171(107736) |
R835872 (2021) |
Exit |
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Requia WJ, Roig HL, Koutrakis P, Adams MD. Modeling spatial patterns of traffic emissions across 5570 municipal districts in Brazil. Journal of Cleaner Production 2017;148:845-853. |
R835872 (2016) R835872C001 (Final) R834798 (Final) |
Exit Exit Exit |
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Requia WJ, Adams MD, Arain A, Koutrakis P, Lee W-C, Ferguson M. Spatio-temporal analysis of particulate matter intake fractions for vehicular emissions: hourly variation by micro-environments in the Greater Toronto and Hamilton Area, Canada. Science of the Total Environment 2017;599-600:1813-1822. |
R835872 (2016) R835872C001 (Final) R834798 (Final) |
Exit Exit Exit |
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Requia WJ, Dalumpines R, Adams MD, Arain A, Ferguson M, Koutrakis P. Modeling spatial patterns of link-based PM2.5 emissions and subsequent human exposure in a large Canadian metropolitan area. Atmospheric Environment 2017;158:172-180. |
R835872 (2016) R835872C001 (Final) R834798 (Final) |
Exit Exit Exit |
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Requia WJ, Adams MD, Arain A, Koutrakis P, Ferguson M. Carbon dioxide emissions of plug-in hybrid electric vehicles: a life-cycle analysis in eight Canadian cities. Renewable and Sustainable Energy Reviews 2017;78:1390-1396. |
R835872 (2016) R835872C001 (Final) R835872C005 (2016) R834798 (Final) |
Exit Exit Exit |
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Requia WJ, Higgins CD, Adams MD, Mohamed M, Koutrakis P. The health impacts of weekday traffic: a health risk assessment of PM2.5 emissions during congested periods. Environment International 2018;111:164-176. |
R835872 (2016) R835872 (2017) R835872C001 (Final) R834798 (Final) |
Exit Exit Exit |
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Requia WJ, Coull BA, Koutrakis P. Regional air pollution mixtures across the continental US. Atmospheric Environment 2019;213(5):258-272. |
R835872 (2018) R834798 (Final) |
Exit Exit |
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Requia W, Di Q, Silvern R, Kelly J, Koutrakis P, Mickley L, Sulprizio M, Amini H, Schwartz J. An ensemble learning approach for estimating high spatiotemporal resolution of ground-level ozone in the contiguous United States. Environmental Science & Technology 2020;54(18):11037-11047. |
R835872 (2020) R835872C001 (Final) R834798 (Final) |
Exit Exit |
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Requia W, Amini H, Mukherjee R, Gold D, Schwartz J. Health impacts of wildfire-related air pollution in Brazil:a nationwide study of more than 2 million hospital admissions between 2008 and 2018. NATURE COMMUNICATIONS 2021;12(1):6555. |
R835872 (2020) |
Exit Exit |
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Rhee J, Dominici F, Zanobetti A, Schwartz J, Wang Y, Di Q, Christiani D. Risk of acute respiratory distress syndrome among older adults living near construction and manufacturing sites. Epidemiology 2020;31(4):468-477. |
R835872 (2020) R835872C003 (Final) |
Exit |
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Romero-Guiterrez C, Koutrakis P, Liu M, Vieria C, Coull B, Maher E, Zhang J, Garshick E. Radon decay product particle radioactivity and oxidative stress biomarkers in patients with COPD. ENVIRONMENTAL RESEARCH 2024;240(Part 2):117505 |
R835872 (Final) R834798 (Final) |
Exit |
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Rosa MJ, Hsu HH, Just AC, Brennan KJ, Bloomquist T, Kloog I, Pantic I, Garcia AM, Wilson A, Coull BA, Wright RO. Association between prenatal particulate air pollution exposure and telomere length in cord blood:Effect modification by fetal sex. Environmental Research 2019;172:495-501. |
R835872 (2019) R835872C002 (Final) R835872C003 (Final) |
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Sade M, Shi L, Colicino E, Amini H, Schwartz J, Di Q, Wright R. Long-term air pollution exposure and diabetes risk in American older adults:A national secondary data-based cohort study. ENVIRONMENTAL POLLUTION 2023;320(121056). |
R835872 (2021) |
Exit |
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Scheerens C, Nurhussein L, Algan A, Synn A, Coull B, Koutrakis P, Rice M. The impact of personal and outdoor temperature exposure during cold and warm seasons on lung function and respiratory symptoms in COPD. ERJ - OPEN RESEARCH 2022;8(1):00574-2021 |
R835872 (2020) R835872C003 (Final) |
Exit |
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Schiff J, Vieira C, Garshick E, Wang V, Blomberg A, Gold D, Schwartz J, Tracy S, Vokanas P, Koutrakis P. The role of solar and geomagnetic activity in endothelial activation and inflammation in the NAS cohort. PLOS ONE 2022;17(7) |
R835872 (2021) R835872C001 (Final) R835872C003 (Final) |
Exit |
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Schwartz JD, Di Q, Requia WJ, Dominici F, Zanobetti A. A Direct Estimate of the Impact of PM2.5, NO2, and O3 Exposure on Life Expectancy Using Propensity Scores. Epidemiology 2021; 32(4):469-476. |
R835872 (2020) R835872C003 (Final) |
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Schwartz J, Wang Y, Yan K, Yitshaak-Sade M, Dominici F, Zanobetti A. Estimating the Effects of PM2.5 on Life Expectancy Using Causal Modeling Methods. ENVIRONMENTAL HEALTH PERSPECTIVES 2018;126(12):127002. |
R835872 (2020) |
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Schwartz J, Yitshak-Sade M, Zanobetti A, Di Q, Dominici F, Mittleman M. A self-controlled approach to survival analysis, with application to air pollution and mortality. ENVIRONMENTAL INTERNATIONAL 2021;157(106861). |
R835872 (2020) R835872C003 (Final) |
Exit Exit |
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Schwartz J, Wei Y, Yitshak-Sade M, Di Q, Dominici F, Zanobetti A. A national difference in differences analysis of the effect of PM2.5 on annual death rates. Environ Res 2021; 194:110649. |
R835872C003 (Final) |
Exit Exit |
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Schwartz J, Bind MA, Koutrakis P. (2017) Estimating causal effects of local air pollution on daily deaths:effect of low levels. Environ Health Perspect 125:23–29; http://dx.doi.org/10.1289/EHP232. |
R835872C003 (2016) |
not available |
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Shen L, Mickley LJ. Effects of El Niño on summertime ozone air quality in the eastern United States. Geophysical Research Letters 2017;44(24):12543-12550. |
R835872 (2016) R835872 (2017) R835872C001 (Final) R835755 (2017) |
Exit Exit |
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Shen L, Mickley LJ, Leibensperger EM, Li M. Strong dependence of U.S. summertime air quality on the decadal variability of Atlantic sea surface temperatures. Geophysical Research Letters 2017;44(24):12527-12535. |
R835872 (2016) R835872 (2017) R835872C001 (Final) |
Exit Exit |
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Shen L, Mickley LJ, Murray LT. Influence of 2000–2050 climate change on particulate matter in the United States:results from a new statistical model. Atmospheric Chemistry and Physics 2017;17(6):4355-4367. |
R835872 (2016) R835872 (2017) R835872C001 (Final) R835755 (2017) |
Exit Exit |
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Shen L, Mickley LJ. Seasonal prediction of US summertime ozone using statistical analysis of large scale climate patterns. Proceedings of the National Academy of Sciences of the United States of America 2017;114(10):2491-2497. |
R835872 (2016) R835872 (2017) |
Exit Exit |
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Shen L, Mickley L, Seibensperger E, Li M. Strong Dependence of Summertime Air Quality on the Decadal Variability of Atlantic Sea Surface Temperatures. GEOPHYSICAL RESEARCH LETTERS 2017;44(24):12527-12535. |
R835872 (2020) |
Exit Exit |
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Shi L, Wu X, Danesh Yazdi M, Braun D, Abu Awad Y, Wei Y, Liu P, Di Q, Wang Y, Schwartz J, Dominici F, Kioumourtzoglou M-A, Zanobetti A. Long-term effects of PM2·5 on neurological disorders in the American Medicare population:a longitudinal cohort study. The Lancet Planetary Health 2020; 4(12):e557-e565. |
R835872C003 (Final) R834677 (Final) |
Exit Exit Exit |
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Silva E, Huang S, Lawrence J, Martins MAG, Li J, Koutrakis P. Trace element concentrations in ambient air as a function of distance from road. J Air Waste Manag Assoc 2021; 71(2):129-136. |
R835872C001 (Final) |
Exit Exit |
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Stern RA, Koutrakis P, Martins MAG, Lemos B, Dowd SE, Sunderland EM, Garshick E. Characterization of hospital airborne SARS-CoV-2. Respir Res 2021; 22(1):73. |
R835872 (2020) R835872C001 (Final) |
Exit Exit |
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Stern R, Koutrakis P, Martins M, Lemos B, Dowd S, Sunderland E, Garchick E. Characterization of Airborne SARS-CoV-2 in a Veterans Affairs Medical Center. SCIENCE OF THE TOTAL ENVIRONMENT 2020;712(136597). |
R835872 (2020) |
Exit |
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Stern R, Charness M, Gupta K, Koutrakis P, Linsenmeyer K, Madjarov R, Martins M, Lemos B, Dowd S, Harshick E. Concordance of SARS-CoV-2 RNA in Aerosols From a Nurses Station and in Nurses and Patients During a Hospital Ward Outbreak. JAMA NETWORK OPEN 2022;5(6):e2216176. |
R835872 (2020) R835872C001 (Final) |
Exit |
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Stern R, Lawrence J, Wolfson J, Li L, Koutrakis P. Radon sampling methodologies: A case for accurate, accessible measurements using household instruments. JOURNAL OF THE AIR & WASTE MANAGEMENT ASSOCIATION 2023;73(7):519-524 |
R835872 (Final) |
Exit |
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Tang CH, Kourakis P, Schwartz J, Coull BA, Di Q. Trends and spatial patterns of fine resolution aerosol optical depth-derived PM2.5 emissions in Northeast United States from 2002 to 2013. Journal of the Air & Waste Management Association 2017;67(1):64-74. |
R835872 (2016) R835872 (2017) R835872 (2020) R834798 (Final) |
Exit Exit Exit |
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Tang CH, Coull BA, Schwartz J, Lyapustin A, Di Q, Koutrakis P. Developing particle emission inventories using remote sensing (PEIRS). Journal of the Air & Waste Management Association 2017;67(1):53-63. |
R835872 (2016) R835872 (2017) R835872C001 (Final) R834798 (Final) |
Exit Exit Exit |
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Tang CH, Garshick E, Grady S, Coull B, Schwartz J, Koutrakis P. Development of a modeling approach to estimate indoor-to-outdoor sulfur ratios and predict indoor PM2.5 and black carbon concentrations for Eastern Massachusetts households. Journal of Exposure Science & Environmental Epidemiology 2018;28(2):125-130. |
R835872 (2016) R835872C001 (Final) R835872C002 (Final) |
Exit Exit |
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Tang CH, Garshick E, Grady S, Coull B, Schwartz J, Koutrakis P. Development of a modeling approach to estimate indoor-to-outdoor sulfur ratios and predict indoor PM2.5 and black carbon concentrations for Eastern Massachusetts households. Journal of Exposure Science and Environmental Epidemiology 2018;28(2):125. |
R835872 (2017) R835872 (2018) |
Exit |
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Thomas E, Braun D, Kioumourtzoglou M, Trippa L, Wasfy J, Dominici F. A Bayesian Multi-Outcome Analysis of Fine Particulate Matter and Cardiorespiratory Hospitalizations. EPIDEMIOLOGY 2022;33(2):176-184. |
R835872 (2020) |
Exit Exit |
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Vieira CL, Koutrakis P, Huang S, Grady S, Hart JE, Coull BA, Laden F, Requia W, Schwartz J, Garshick E. Short-term effects of particle gamma radiation activities on pulmonary function in COPD patients. Environ Res 2019;221-227. |
R835872 (2016) R835872 (2019) R835872C001 (Final) R834798 (Final) |
Exit Exit Exit |
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Vieira C, Koutrakis P. The impact of solar activity on ambient ultrafine particle concentrations:An analysis based on 19-year measurements in Boston, USA. ENVIRONMENTAL RESEARCH 2021;201(111532). |
R835872 (2020) R835872C001 (Final) R834798 (Final) |
Exit Exit |
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Vohra K, Vodonos A, Schwartz J, Marais EA, Sulprizio MP, Mickley LJ. Global mortality from outdoor fine particle pollution generated by fossil fuel combustion:Results from GEOS-Chem. Environ Res 2021; 195:110754. |
R835872C001 (Final) R835872C003 (Final) |
Exit Exit |
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Wag Y, Qiu X, Schwartz J. Long-Term Exposure to Ambient PM2.5 and Hospitalizations for Myocardial Infarction Among US Residents:A Difference-in-Differences Analysis. JOURNAL OF THE AMERICAN HEART ASSOCIATION 2023;12(18):e029428. |
R835872 (Final) |
Exit |
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Wang A, Leung M, Modest A, Vieira C, Hacker M, Schwartz J, Coull B, Koutrakis P. Associations of solar activity and related exposures with fetal growth. SCIENCE OF THE TOTAL ENVIRONMENT 2023;885(163862). |
R835872 (Final) |
Exit |
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Wang C, Cardenas A, Hutchinson J, Just A, Heiss J, Hou L, Zheng Y, Coull B, Kosheleva A, Koutrakis P, Baccarelli A, Schwartz J. Short-and intermediate-term exposure to ambient fine particulate elements and leukocyte epigenome-wide DNA methylation in older men:the Normative Aging Study. ENVIRONMENTAL INTERNATIONAL 2022;158. |
R835872 (2020) R835872C002 (Final) R835872C003 (Final) |
Exit Exit |
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Wang V, Vieira Z, Garshick E, Schwartz J, Garshick M, Vokonas P, Koutrakis P. Solar activity is associated with diastolic and systolic blood pressure in elderly adults. Journal of the American Heart Association 2021;10(21):e021006. |
R835872 (2020) R835872C001 (Final) R835872C003 (Final) |
Exit Exit |
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Wang V, Leung M, Liu M, Modest A, Hacker M, Gupta M, Vieira C, Weisskiph M, Schwartz J, Coull B, Papatheodorou S, Koutrakis P. Association between gestational exposure to solar activity and pregnancy loss using live births from a Massachusetts-based medical center. ENVIRIONMENTAL RESEARCH 2024;242(117742) |
R835872 (Final) |
Exit |
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Wang Y, Shi L, Lee M, Liu P, Di Q, Zanobetti A, Schwartz JD. Long-term exposure to PM2.5 and mortality among older adults in the Southeastern US. Epidemiology 2017;28(2):207-214. |
R835872 (2016) R835872 (2017) R835872C003 (Final) R836156 (2017) R836156 (2020) |
Exit |
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Wang Y, Lee M, Liu P, Shi L, Yu Z, Awad YA, Zanobetti A, Schwartz JD. Doubly robust additive hazards models to estimate effects of a continuous exposure on survival. Epidemiology 2017;28(6):771-779. |
R835872 (2016) R835872 (2017) |
Exit |
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Wang Y, Nordio F, Nairn J, Zanobetti A, Schwartz JD. Accounting for adaptation and intensity in projecting heat wave-related mortality. Environmental Research 2018;161:464-471. |
R835872 (2016) R835872 (2017) |
Exit Exit Exit |
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Wang Y, Hong C, Palmer N, Di Q, Schwartz J, Kohane I, Cai T. A fast divide-and-conquer sparse Cox Regression. BIOSTATISTICS 2021;22(2):381-401 |
R835872 (2020) |
Exit |
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Wang Y, Yazdi M, Wei Y, Schwartz J. Air pollution below US regulatory standards and cardiovascular diseases using a double negative control approach. NATURE COMMUNICATIONS 2024;15(1). |
R835872 (Final) |
Exit |
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Wang Z, Koutrakis P, Liu M, Vieira C, Coull B, Maher E, Moy M, Huang S, Garshick E. Residential radon decay products are associated with cough and phlegm in patients with COPD. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 2024;282. |
R835872 (Final) R834798 (Final) |
Exit |
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Ward-Caviness CK, Weaver AM, Buranosky M, Pfaff ER, Neas LM, Devlin RB, Schwartz J, Di Q, Cascio WE, Diaz-Sanchez D. Associations Between Long-Term Fine Particulate Matter Exposure and Mortality in Heart Failure Patients. J Am Heart Assoc 2020; 9(6):e012517. |
R835872C003 (Final) R834798 (Final) |
Exit Exit |
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Ward-Caviness CK, Danesh Yazdi M, Moyer J, Weaver AM, Cascio WE, Di Q, Schwartz JD, Diaz-Sanchez D. Long-Term Exposure to Particulate Air Pollution Is Associated With 30-Day Readmissions and Hospital Visits Among Patients With Heart Failure. J Am Heart Assoc 2021; 10(10):e019430. |
R835872 (2020) R835872C003 (Final) |
Exit Exit |
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Wei Y, Wang Y, Wu X, Di Q, Shi L, Koutrakis P, Zanobetti A, Dominici F, Schwartz J. Causal Effects of Air Pollution on Mortality Rate in Massachusetts. AMERICAN JOURNAL OF EPIDEMIOLOGY 2020;189(11):1316-1323. |
R835872 (2020) R835872C003 (Final) R836156 (Final) |
Exit Exit |
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Wei Y, Yazdi M, Di Q, Dominici F, Zanobetti A, Schwartz J. Emulating causal dose-response Relations between air pollutants and mortality in the Medicare population. Environmental Health 2021;270(1). |
R835872 (2020) R835872C003 (Final) |
Exit Exit |
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Wei Y, Coull B, Koutrakis P, Yang J, Li L, Zanobetti A, Schowatz J. Assessing additive effects of air pollutants on mortality rate in Massachusetts. ENVIRONMENTAL HEALTH 2021;20(1):19. |
R835872 (2020) R835872C002 (Final) R835872C003 (Final) R836156 (Final) |
Exit Exit |
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Wei Y, Qiu X, Yazdi M, Shtein A, Shi L, Yang J, Peralta A, Coull B, Schwartz J. The Impact of Exposure Measurement Error on the Estimated Concentration-Response Relationship between Long-Term Exposure to PM2.5 and Mortality. ENVIRONMENTAL HEALTH PERSPECTIVES 2022;130(7):77006. |
R835872 (2021) R835872C003 (Final) |
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Wikle N, Hanks E, Henneman L, Zigler C. A Mechanistic Model of Annual Sulfate Concentrations in the United States. JOURNALS OF THE AMERICAN STATISTICAL ASSOCIATION 2022;. |
R835872 (2020) R835872C004 (Final) R834798 (Final) |
Exit Exit |
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Wright R, Shu HL, Coull B, Simon M, Hudda N, Schwartz J, Kloog I, Durant J. Prenatal ambient ultrafine particle exposure and childhood asthma in the Northeastern United States. American Journal of Respiratory and Critical Care Medicine 2021;204(7):788-796. |
R835872 (2020) R835872C002 (Final) R835872C003 (Final) |
Exit Exit |
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Wu X, Nethery RC, Sabath MB, Braun D, Dominici F. Air pollution and COVID-19 mortality in the United States:Strengths and limitations of an ecological regression analysis. Science Advances 2020; 6(45) |
R835872 (2020) R835872C004 (Final) R834677 (Final) |
Exit Exit |
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Wu X, Braun D, Schwartz J, Kioumourtzoglou M, Dominici F. Evaluating the impact of long-term exposure to fine particulate matter on mortality among the elderly. SCIENCE ADVANCES 2020;6(29):eaba5692. |
R835872 (2020) R835872C003 (Final) R835872C004 (Final) R834798 (Final) |
Exit Exit |
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Xiong J, Li J, Wu X, Wolfson J, Lawrence J, Stern R, Koutrakis P, Wei J, Huang S. The association between daily-diagnosed COVID-19 morbidity and short-term exposure to PM1 is larger than associations with PM2.5 and PM10. ENVIRONMENTAL RESEARCH 2022;210(113016). |
R835872 (2020) R835872C001 (Final) |
Exit Exit |
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Yan M, Dominici F, Wang Y, Al-Hamdan M, Rosson W, Schumacher A, Guikema S, Nagzamen S, Peel J, Peng R, Anderson G. Tropical Cyclone Exposures and Risks of Emergency Medicare Hospital Admission for Cardiorespiratory Diseases in 175 Urban United States Counties, 1999-2010. EPIDEMIOLOGY 2021;32(3):315-328. |
R835872 (2020) |
Exit |
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Yazdi M, Wei T, Requia W, Shi L, Sabath M, Dominici F, Schwartz J. The effect of long-term exposure to air pollution and seasonal temperature on hospital admissions with cardiovascular and respiratory disease in the United States:A difference-in-differences analysis. SCIENCE OF THE TOTAL ENVIRONMENT 2022;843(156855). |
R835872 (2020) R835872C003 (Final) |
Exit Exit |
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Yitshak-Sade M, Nethery R, Schwartz JD, Mealli F, Dominici F, Di Q, Abu Awad Y, Ifergane G and Zanobetti A. PM2.5 and hospital admissions among Medicare enrollees with chronic debilitating brain disorders. Science of The Total Environment 2021; 755. |
R835872C003 (Final) |
Exit |
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Yu S, Kang C, Liu M, Kotrakis P. PM2.5 sources affecting particle radioactivity in Boston, Massachusetts. ATHMOSPHERIC ENVIRONMENT 2021;259. |
R835872 (2020) R835872C001 (Final) R834798 (Final) |
Exit Exit |
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Yu X, Rahman M, Carter S, Lin J, Zhuang Z, Chow T, Lurmann F, Kleeman M, Martinez M, van Donkelaar A, Martin R, Eckel S, Chen Z, Levitt P, Schwartz J, Hackman D, Chen J, Mcconnell R, Xiang A. Prenatal air pollution, maternal immune activation, and autism spectrum disorder. ENVIRONMENTAL INTERNATIONAL 2023;179:108148 |
R835872 (Final) |
Exit |
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Yu X, Kleeman M, Lin J, Chow T, Martinez M, Chen Z, Chen J, Eckel S, Schwartz J, Lurmann F, McConnell R, Ziang A, Rahman M. Decomposing the variance: The unique and shared associations of fine and ultrafine particulate matter exposed during pregnancy with child autism spectrum disorder. SCIENCE OF THE TOTAL ENVIRONMENT 2024; |
R835872 (Final) |
Exit |
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Yuan Y, Alahmad B, Kang C, Al-Marri F, Kommula V, Bouhamra W, Koutrakis P. Dust events and indoor air quality in residential homes in Kuwait. International Journal of Environmental Research and Public HealthH 2020;17(7):2433. |
R835872 (2020) R835872C001 (Final) |
Exit Exit |
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Zanobetti A, Coull BA, Kloog I, Sparrow D, Vokonas PS, Gold DR, Schwartz J. Fine-scale spatial and temporal variation in temperature and arrhythmia episodes in the VA Normative Aging Study. Journal of the Air & Waste Management Association 2017;67(1):96-104. |
R835872 (2016) R835872C003 (Final) R832416 (Final) R834798 (Final) R834798C002 (Final) R834798C004 (Final) R834798C005 (Final) |
Exit Exit |
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Zanobetti A, Coull BA, Luttmann-Gibson H, van Rossem L, Rifas-Shiman SL, Kloog I, Schwartz JD, Oken E, Bobb JF, Koutrakis P, Gold DR. Ambient particle components and newborn blood pressure in Project Viva. Journal of the American Heart Association 2021; 10(1):e016935. |
R835872C002 (Final) R835872C003 (Final) |
Exit Exit |
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Zarate R, Zigler C, Cubbin C, Matsui E. Neighborhood-level variability in asthma-related emergency drtment visits in Central Texas. THE JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 2021;148(5):1232-1269. |
R835872 (2020) |
Exit Exit |
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Zemplenyi M, Meyer MJ, Cardenas A, Hivert M-F, Rifas-Shiman SL, Gibson H, Kloog I, Schwartz J, Oken E, DeMeo DL, Gold DR, Coull BA. Function-on-function regression for the identification of epigenetic regions exhibiting windows of susceptibility to environmental exposures. Annals of Applied Statistics 2021; 15(3):1366-1385. |
R835872 (2020) R835872C002 (Final) |
Exit Exit |
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Zhai T, Vieira C, Vokona P, Baccarelli A, Nagel Z, Schwartz J, Koutrakis P. Annual space weather fluctuations and telomere length dynamics in a longitudinal cohort of older men: the Normative Aging Study. JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY 2023; |
R835872 (Final) |
Exit |
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Zhang S, Breitner S, Cascio WE, Devlin RB, Neas LM, Ward-Caviness C, Diaz-Sanchez D, Kraus WE, Hauser ER, Schwartz J, Peters A, Schneider A. Association between short-term exposure to ambient fine particulate matter and myocardial injury in the CATHGEN cohort. Environ Pollut 2021; 275:116663. |
R835872 (2020) R835872C003 (Final) |
Exit Exit |
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Zhou X, Josey K, Kamareddine L, Caine M, Liu T, Mickley L, Cooper M, Dominici F. Excess of COVID-19 cases and deaths due to fine particulate matter exposure during the 2020 wildfires in the United States. SCIENCE ADVANCES 2021;7(33):eabi8789. |
R835872 (2020) |
Exit Exit |
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Zigler CM, Choirat C, Dominici F. Impact of National Ambient Air Quality Standards nonattainment designations on particulate pollution and health. Epidemiology 2018;29(2):165-174. |
R835872 (2016) R835872C004 (Final) R836156 (2018) R836156 (2020) |
Exit |
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Zigler CM, Papadogeorgou G. Bipartite Causal Inference with Interference. Statistical Science 2021; 36(1):109-123. |
R835872 (2020) |
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Zigler C. Invited Commentary: The Promise and Pitfalls of Causal Inference With Multivariate Environmental Exposures. AMERICAN JOURNAL OF EPIDEMIOLOGY 2021;190(12):2658-2661 |
R835872 (2020) R835872C004 (Final) |
Exit |
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Zigler C, Liu V, Mealli F, Forastiere L. Bipartite interference and air pollution transport: estimating health effects of power plant interventions. BIOSTATISTICS 2025;26(1) |
R835872 (Final) R835872C004 (Final) |
Exit |
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Vierira CLZ, Link M, Garschick E, Peralta A, Luttman-Gibson H, Laden F, Liu M, Gold D, Koutrakis P. Solar and geomagnetic activity enhance the effects of air pollutants on atrial fibrillation. Eurspace 2022;24(5):713-720. |
R835872 (2020) R835872C001 (Final) R835872C003 (Final) R834798 (Final) |
Exit |
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Bind M-A, Peters A, Koutrakis P, Coull B, Vokonas P and Schwartz J. Quantile Regression Analysis of the Distributional Effects of Air Pollution on Blood Pressure, Heart Rate Variability, Blood Lipids, and Biomarkers of Inflammation in Elderly American Men:The Normative Aging Study. Environmental Health Perspectives 2016; 124(8):1189-1198. |
R835872C003 (Final) R834798 (Final) |
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Ierodiakonou D, Zanobetti A, Coull BA, Melly S, Postma DS, Boezen HM, Vonk JM, Williams PV, Shapiro GG, McKone EF, Hallstrand TS, Koenig JQ, Schildcrout JS, Lumley T, Fuhlbrigge AN, Koutrakis P, Schwartz J, Weiss ST and Gold DR. Ambient air pollution, lung function, and airway responsiveness in asthmatic children. Journal of Allergy and Clinical Immunology 2016; 137(2):390-399. |
R835872C002 (Final) R834798 (Final) |
Exit Exit Exit |
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Bind M-AC, Coull BA, Baccarelli A, Tarantini L, Cantone L, Vokonas P and Schwartz J. Distributional changes in gene-specific methylation associated with temperature. Environmental Research 2016; 150:38-46. |
R835872C003 (Final) |
Exit |
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Wilson A, Chiu YH, Hsu HH, Wright RO, Wright RJ, Coull BA. Potential for bias when estimating critical windows for air pollution in children’s health. American Journal of Epidemiology 2017;186(11):1281-1289. |
R835872 (2018) R835872C002 (Final) R834798 (Final) |
Exit |
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Dominici F, Zigler C. Best practices for gauging evidence of causality in air pollution epidemiology. American Journal of Epidemiology 2017;186(12):1303-1309. |
R835872 (2017) R835872C004 (Final) R834798 (Final) |
Exit |
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Awad YA, Koutrakis P, Coull BA, Schwartz J. A spatio-temporal prediction model based on support vector machine regression: ambient black carbon in three New England States. Environmental Research 2017;159: 427-434. |
R835872 (2017) R835872C002 (Final) R834798 (Final) |
Exit |
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Lin C, Christiani D, Lin RT. 0059 A global perspective on coal-fired power plants and lung cancer mortality. Occupational and Environmental Medicine 2017;74:A16. |
R835872 (2018) R835872C004 (Final) |
Exit |
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Prada D, Zhong J, Colicino E, Zanobetti A, Schwartz J, Dagincourt N, Fang SC, Kloog I, Zmuda JM, Holick M, Herrera LA. Association of air particulate pollution with bone loss over time and bone fracture risk:analysis of data from two independent studies. The Lancet Planetary Health 2017;1(8):e337-347. |
R835872 (2017) |
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Di Q, Dai L, Wang Y, Zanobetti A, Choirat C, Schwartz JD, Dominici F. Association of short-term exposure to air pollution with mortality in older adults. JAMA 2017;318(24):2446-2456. |
R835872C003 (Final) |
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Peng C, Cayir A, Sanchez-Guerra M, Di Q, Wilson A, Zhong J, Kosheleva A, Trevisi L, Colicino E, Brennan K, Dereix AE. Associations of annual ambient fine particulate matter mass and components with mitochondrial DNA abundance. Epidemiology 2017;28(6):763-770. |
R835872 (2017) R835872 (2018) R835872C003 (Final) |
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Wilson A, Chiu YH, Hsu HH, Wright RO, Wright RJ, Coull BA. Bayesian distributed lag interaction models to identify perinatal windows of vulnerability in children’s health. Biostatistics 2017;18(3):537-552. |
R835872 (2017) R835872C002 (Final) |
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Rosa MJ, Just AC, Guerra MS, Kloog I, Hsu HH, Brennan KJ, García AM, Coull B, Wright RJ, Rojo MM, Baccarelli AA. Identifying sensitive windows for prenatal particulate air pollution exposure and mitochondrial DNA content in cord blood. Environment International 2017;98:198-203. |
R835872 (2017) R835872C002 (Final) |
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Wilson A, Chiu YH, Hsu HH, Wright RO, Wright RJ, Coull BA. Potential for bias when estimating critical windows for air pollution in children’s health. American Journal of Epidemiology 2017;186(11):1281-1289. |
R835872 (2017) |
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Rosa MJ, Pajak A, Just AC, Sheffield PE, Kloog I, Schwartz J, Coull B, Enlow MB, Baccarelli AA, Huddleston K, Niederhuber JE. Prenatal exposure to PM2.5 and birth weight:a pooled analysis from three North American longitudinal pregnancy cohort studies. Environment International 2017;107:173-180. |
R835872 (2017) R835872C002 (Final) |
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Bose S, Chiu YH, Hsu HH, Di Q, Rosa MJ, Lee A, Kloog I, Wilson A, Schwartz J, Wright RO, Cohen S. Prenatal nitrate exposure and childhood asthma:influence of maternal prenatal stress and fetal sex. American Journal of Respiratory and Critical Care Medicine 2017;196(11):1396-1403. |
R835872 (2017) R835872 (2018) R835872C002 (Final) |
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Chiu YH, Hsu HH, Wilson A, Coull BA, Pendo MP, Baccarelli A, Kloog I, Schwartz J, Wright RO, Taveras EM, Wright RJ. Prenatal particulate air pollution exposure and body composition in urban preschool children:examining sensitive windows and sex-specific associations. Environmental Research 2017;158:798-805. |
R835872 (2017) R835872C002 (Final) R835872C003 (Final) |
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Rosa MJ, Just AC, Kloog I, Pantic I, Schnaas L, Lee A, Bose S, Chiu YH, Hsu HH, Coull B, Schwartz J. Prenatal particulate matter exposure and wheeze in Mexican children:effect modification by prenatal psychosocial stress. Annals of Allergy, Asthma & Immunology 2017;119(3):232-237. |
R835872 (2017) |
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Jhun I, Gaffin JM, Coull BA, Huffaker MF, Petty CR, Sheehan WJ, Baxi SN, Lai PS, Kang C-M, Wolfson JM, Gold DR, Koutrakis P and Phipatanakul W. School Environmental Intervention to Reduce Particulate Pollutant Exposures for Children with Asthma. The Journal of Allergy and Clinical Immunology:In Practice 2017; 5(1):154-159.e153. |
R835872C003 (Final) |
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Peng C, Sanchez-Guerra M, Wilson A, Mehta AJ, Zhong J, Zanobetti A, Brennan K, Dereix AE, Coull BA, Vokonas P, Schwartz J. Short-term effects of air temperature and mitochondrial DNA lesions within an older population. Environment International 2017;103:23-29. |
R835872 (2017) |
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Chudnovsky AA, Koutrakis P, Kostinski A, Proctor SP and Garshick E. Spatial and temporal variability in desert dust and anthropogenic pollution in Iraq, 1997–2010. Journal of the Air & Waste Management Association 2017; 67(1):17-26. |
R835872C001 (Final) |
not available |
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Kioumourtzoglou MA, Power MC, Hart JE, Okereke OI, Coull BA, Laden F, Weisskopf MG. The association between air pollution and onset of depression among middle-aged and older women. American Journal of Epidemiology 2017;185(9):801-809. |
R835872 (2017) R835872C002 (Final) |
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Gaffin JM, Hauptman M, Petty CR, Sheehan WJ, Lai PS, Wolfson JM, Gold DR, Coull BA, Koutrakis P, Phipatanakul W. Nitrogen dioxide exposure in school classrooms of inner-city children with asthma. Journal of Allergy and Clinical Immunology 2018;141(6):2249-2255. |
R835872 (2018) R835872C002 (Final) R834798 (Final) |
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Li W, Dorans KS, Wilker EH, Rice MB, Kloog I, Schwartz JD, Koutrakis P, Coull BA, Gold DR, Meigs JB, Fox CS. Ambient air pollution, adipokines, and glucose homeostasis:The Framingham heart study. Environment International 2018;111:14-22. |
R835872 (2018) R834798 (Final) |
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Cutler D, Dominici F. A breath of bad air:cost of the Trump environmental agenda may lead to 80 000 extra deaths per decade. JAMA 2018;319(22):2261-2262. |
R835872 (2018) R835872C004 (Final) |
not available |
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Lin CK, Lin RT, Chen PC, Wang P, De Marcellis-Warin N, Zigler C, Christiani DC. A global perspective on sulfur oxide controls in coal-fired power plants and cardiovascular disease. Scientific Reports 2018;8(1):2611. |
R835872 (2018) R835872C004 (Final) |
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Schwartz J, Fong K, Zanobetti A. A national multicity analysis of the causal effect of local pollution, NO2, and PM2.5 on mortality. Environmental Health Perspectives 2018;126(8):087004. |
R835872 (2018) R835872C003 (Final) |
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Papadogeorgou G, Choirat C, Zigler CM. Adjusting for unmeasured spatial confounding with distance adjusted propensity score matching. Biostatistics 2018;20(2):256-272. |
R835872 (2017) R835872 (2018) R835872C004 (Final) |
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Requia WJ, Arain A, Koutrakis P and Dalumpines R. Assessing particulate matter emissions from future electric mobility and potential risk for human health in Canadian metropolitan area. Air Quality, Atmosphere & Health 2018; 11(9):1009-1019. |
R835872C001 (Final) |
not available |
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Sheffield PE, Speranza R, Chiu YH, Hsu HH, Curtin PC, Renzetti S, Pajak A, Coull B, Schwartz J, Kloog I, Wright RJ. Association between particulate air pollution exposure during pregnancy and postpartum maternal psychological functioning. PloS One 2018;13(4):e0195267. |
R835872 (2018) R835872C002 (Final) |
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Nyhan MM, Coull BA, Blomberg AJ, Vieira CL, Garshick E, Aba A, Vokonas P, Gold DR, Schwartz J, Koutrakis P. Associations between ambient particle radioactivity and blood pressure:the NAS (Normative Aging Study). Journal of the American Heart Association 2018;7(6):e008245. |
R835872 (2018) R835872C001 (Final) R835872C002 (Final) R835872C003 (Final) |
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Rokoff LB, Rifas-Shiman SL, Coull BA, Cardenas A, Calafat AM, Ye X, Gryparis A, Schwartz J, Sagiv SK, Gold DR, Oken E. Cumulative exposure to environmental pollutants during early pregnancy and reduced fetal growth:the project viva cohort. Environmental Health 2018;17(1):19. |
R835872 (2018) R835872C002 (Final) R834798 (Final) |
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Schwartz JD, Wang Y, Kloog I, Yitshak-Sade MA, Dominici F, Zanobetti A. Estimating the effects of PM on life expectancy using causal modeling methods. Environmental Health Perspectives 2018;126(12):127002.. |
R835872 (2019) R835872C004 (Final) |
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Ananth CV, Kioumourtzoglou MA, Huang Y, Ross Z, Friedman AM, Williams MA, Wang S, Mittleman MA, Schwartz J. Exposures to air pollution and risk of acute-onset placental abruption:a case-crossover study. Epidemiology 2018;29(5):631-638. |
R835872 (2018) R835872C003 (Final) |
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Wurth R, Kioumourtzoglou M-A, Tucker KL, Griffith J, Manjourides J and Suh H. Fine particle sources and cognitive function in an older Puerto Rican cohort in Greater Boston:. Environmental Epidemiology 2018; 2(3):e022. |
R835872C003 (Final) |
Exit |
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Requia WJ, Adams MD, Arain A, Papatheodorou S, Koutrakis P and Mahmoud M. Global Association of Air Pollution and Cardiorespiratory Diseases:A Systematic Review, Meta-Analysis, and Investigation of Modifier Variables. American Journal of Public Health 2018; 108(S2):S123-S130. |
R835872C003 (Final) |
Exit |
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Zigler CM, Choirat C, Dominici F. Impact of national ambient air quality standards nonattainment designations on particulate pollution and health. Epidemiology 2018;29(2):165-164. |
R835872 (2017) R835872 (2018) |
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Garshick E, Grady ST, Hart JE, Coull BA, Schwartz JD, Laden F, Moy ML, Koutrakis P. Indoor black carbon and biomarkers of systemic inflammation and endothelial activation in COPD patients. Environmental Research 2018;165:358-364. |
R835872 (2018) R835872C001 (Final) R835872C002 (Final) R835872C003 (Final) |
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Rice MB, Rifas-Shiman SL, Litonjua AA, Gillman MW, Liebman N, Kloog I, Luttmann-Gibson H, Coull BA, Schwartz J, Koutrakis P, Oken E. Lifetime air pollution exposure and asthma in a pediatric birth cohort. Journal of Allergy and Clinical Immunology 2018;141(5):1932-1934. |
R835872 (2018) R835872C002 (Final) R835872C003 (Final) |
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Ljungman PL, Li W, Rice MB, Wilker EH, Schwartz J, Gold DR, Koutrakis P, Benjamin EJ, Vasan RS, Mitchell GF, Hamburg NM. Long-and short-term air pollution exposure and measures of arterial stiffness in the Framingham heart study. Environment International 2018;121:139-147. |
R835872 (2018) R835872C003 (Final) |
Exit |
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Zanobetti A, O’Neill MS. Longer-term outdoor temperatures and health effects:a review. Current Epidemiology Reports 2018;5(2):125-139. |
R835872 (2018) R836156 (2019) R836156 (2020) |
Exit |
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Requia WJ, Koutrakis P and Arain A. Modeling spatial distribution of population for environmental epidemiological studies:Comparing the exposure estimates using choropleth versus dasymetric mapping. Environment International 2018; 119:152-164. |
R835872C001 (Final) |
not available |
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Wilson A, Zigler CM, Patel CJ, Dominici F. Model‐averaged confounder adjustment for estimating multivariate exposure effects with linear regression. Biometrics 2018;74(3):1034-1044. |
R835872 (2017) R835872C004 (Final) R836156 (2019) R836156 (2020) |
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Silvern RF, Jacob DJ, Travis KR, Sherwen T, Evans MJ, Cohen RC, Laughner JL, Hall SR, Ullmann K, Crounse JD, Wennberg PO. Observed NO/NO2 ratios in the upper troposphere imply errors in NO‐NO2‐O3 cycling kinetics or an unaccounted NOx reservoir. Geophysical Research Letters 2018;45(9):4466-4474. |
R835872 (2018) R835872C001 (Final) |
Exit Exit |
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Lee A, Hsu HH, Chiu YH, Bose S, Rosa MJ, Kloog I, Wilson A, Schwartz J, Cohen S, Coull BA, Wright RO. Prenatal fine particulate exposure and early childhood asthma:effect of maternal stress and fetal sex. Journal of Allergy and Clinical Immunology 2018;141(5):1880-1886. |
R835872 (2017) R835872 (2018) R835872C002 (Final) |
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Lee AG, Le Grand B, Hsu HH, Chiu YH, Brennan KJ, Bose S, Rosa MJ, Brunst KJ, Kloog I, Wilson A, Schwartz J. Prenatal fine particulate exposure associated with reduced childhood lung function and nasal epithelia GSTP1 hypermethylation:sex-specific effects. Respiratory Research 2018;19(1):76. |
R835872 (2018) R835872C002 (Final) |
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Bose S, Rosa MJ, Chiu YH, Hsu HH, Di Q, Lee A, Kloog I, Wilson A, Schwartz J, Wright RO, Morgan WJ. Prenatal nitrate air pollution exposure and reduced child lung function:timing and fetal sex effects. Environmental research 2018;167:591-597. |
R835872 (2018) R835872C002 (Final) |
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Brunst KJ, Sanchez-Guerra M, Chiu YH, Wilson A, Coull BA, Kloog I, Schwartz J, Brennan KJ, Enlow MB, Wright RO, Baccarelli AA. Prenatal particulate matter exposure and mitochondrial dysfunction at the maternal-fetal interface:effect modification by maternal lifetime trauma and child sex. Environment International 2018;112:49-58. |
R835872 (2018) R835872C002 (Final) |
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Li W, Nyhan MM, Wilker EH, Vieira CL, Lin H, Schwartz JD, Gold DR, Coull BA, Aba AM, Benjamin EJ, Vasan RS. Recent exposure to particle radioactivity and biomarkers of oxidative stress and inflammation:the Framingham heart study. Environment International 2018;121:1210-1216. |
R835872 (2018) R835872 (2019) |
Exit |
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Sordillo JE, Switkowski KM, Coull BA, Schwartz J, Kloog I, Gibson H, Litonjua AA, Bobb J, Koutrakis P, Rifas-Shiman SL, Oken E. Relation of prenatal air pollutant and nutritional exposures with biomarkers of allergic disease in adolescence. Scientific Reports 2018;8(1):10578. |
R835872 (2018) R835872C002 (Final) |
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Fong K, Kloog I, Coull B, Koutrakis P, Laden F, Schwartz J, James P. Residential greenness and birthweight in the state of Massachusetts, USA. International Journal of Environmental Research and Public Health 2018;15(6):1248. |
R835872 (2018) R835872C003 (Final) R836156 (2019) R836156 (2020) |
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Gaskins AJ, Hart JE, Mínguez-Alarcón L, Chavarro JE, Laden F, Coull BA, Ford JB, Souter I, Hauser R. Residential proximity to major roadways and traffic in relation to outcomes of in vitro fertilization. Environment International 2018;115:239-246.. |
R835872 (2018) R835872C002 (Final) |
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Peng C, den Dekker M, Cardenas A, Rifas-Shiman SL, Gibson H, Agha G, Harris MH, Coull BA, Schwartz J, Litonjua AA, DeMeo DL. Residential proximity to major roadways at birth, DNA methylation at birth and midchildhood, and childhood cognitive test scores:project viva (Massachusetts, USA). Environmental Health Perspectives 2018;126(9):097006. |
R835872 (2018) R835872C002 (Final) |
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Huang S, Lawrence J, Kang CM, Li J, Martins M, Vokonas P, Gold DR, Schwartz J, Coull BA, Koutrakis P. Road proximity influences indoor exposures to ambient fine particle mass and components. Environmental Pollution 2018;243:978-987. |
R835872 (2018) R835872C001 (Final) R835872C002 (Final) |
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Bobb JF, Henn BC, Valeri L, Coull BA. Statistical software for analyzing the health effects of multiple concurrent exposures via Bayesian kernel machine regression. Environmental Health 2018;17(1):67. |
R835872 (2018) R835872C002 (Final) |
Exit |
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Yitshak-Sade M, Bobb JF, Schwartz JD, Kloog I, Zanobetti A. The association between short and long-term exposure to PM2.5 and temperature and hospital admissions in New England and the synergistic effect of the short-term exposures. Science of The Total Environment 2018;639:868-875. |
R835872 (2018) R835872C003 (Final) |
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Di Q, Amini H, Shi L, Kloog I, Silvern R, Kelly J, Sabath MB, Choirat C, Koutrakis P, Lyapustin A, Wang Y. Assessing NO2 concentration and model uncertainty with high spatiotemporal resolution across the contiguous United States using ensemble model averaging. Environmental Science & Technology 2019;54(3):1372-1384. |
R835872 (2019) R835872 (2020) R835872C001 (Final) R834798 (Final) |
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Blomberg AJ, Coull BA, Jhun I, Vieira CL, Zanobetti A, Garshick E, Schwartz J, Koutrakis P. Effect modification of ambient particle mortality by radon:a time series analysis in 108 US cities. Journal of the Air & Waste Management Association 2019;69(3):266-276. |
R835872 (2018) R835872 (2019) R835872 (2020) R835872C001 (Final) R835872C002 (Final) R835872C003 (Final) R834798 (Final) |
Exit Exit |
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Requia WJ, Coull BA, Koutrakis P. Evaluation of predictive capabilities of ordinary geostatistical interpolation, hybrid interpolation, and machine learning methods for estimating PM2.5 constituents over space. Environmental Research 2019;175:421-433. |
R835872 (2018) R835872 (2019) R835872C001 (Final) R835872C002 (Final) R834798 (Final) |
Exit |
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Di Q, Amini H, Shi L, Kloog I, Silvern R, Kelly J, Sabath MB, Choirat C, Koutrakis P, Lyapustin A, Wang Y. An ensemble-based model of PM2.5 concentration across the contiguous United States with high spatiotemporal resolution. Environment International 2019;130:104909. |
R835872 (2019) R835872C001 (Final) R834798 (Final) |
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Requia WJ, Coull BA, Koutrakis P. Multivariate spatial patterns of ambient PM2.5 elemental concentrations in Eastern Massachusetts. 2019;252:1942-1952.. |
R835872 (2018) R835872 (2019) R835872C001 (Final) R834798 (Final) |
Exit |
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Vieira CL, Alvares D, Blomberg A, Schwartz J, Coull B, Huang S, Koutrakis P. Geomagnetic disturbances driven by solar activity enhance total and cardiovascular mortality risk in 263 US cities. Environmental Health 2019;18(1):83. |
R835872 (2019) R835872C001 (Final) R835872C003 (Final) R834798 (Final) |
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Requia WJ, Coull BA, Koutrakis P. The impact of wildfires on particulate carbon in the western USA. Atmospheric Environment 2019;213:1-10.. |
R835872 (2018) R834798 (Final) |
Exit Exit |
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Requia WJ, Coull BA, Koutrakis P. The influence of spatial patterning on modeling PM2.5 constituents in Eastern Massachusetts. Science of The Total Environment 2019;682:247-258. |
R835872 (2018) R835872 (2019) R835872C001 (Final) R835872C002 (Final) R834798 (Final) |
Exit |
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Requia WJ, Jhun I, Coull BA, Koutrakis P. Climate impact on ambient PM2.5 elemental concentration in the United States:a trend analysis over the last 30 years. Environment International 2019;131:104888. |
R835872 (2018) R835872 (2019) R835872C001 (Final) R835872C002 (Final) R834798 (Final) |
Exit |
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Gaskins AJ, Minguez-Alarcon L, Fong KC, Abu Awad Y, Di Q, Chavarro JE, Ford JB, Coull BA, Schwartz J, Kloog I, Attaman J. Supplemental folate and the relationship between traffic-related air pollution and livebirth among women undergoing assisted reproduction. American Journal of Epidemiology 2019;188(9):1595-1604. |
R835872 (2019) R835872C002 (Final) R835872C003 (Final) R834798 (Final) |
Exit Exit |
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Wei Y, Wang Y, Di Q, Choirat C, Wang Y, Koutrakis P, Zanobetti A, Dominici F and Schwartz JD. Short term exposure to fine particulate matter and hospital admission risks and costs in the Medicare population:time stratified, case crossover study. BMJ 2019; 367:l6258. |
R835872 (2019) R835872C003 (Final) R835872C004 (Final) R834798 (Final) |
Exit |
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Borge R, Requia WJ, Yague C, Jhun I and Koutrakis P. Impact of weather changes on air quality and related mortality in Spain over a 25year period [1993-2017]. Environ Int 2019; 133(Pt B):105272. |
R835872 (2020) R835872C001 (Final) R835872C003 (Final) R834798 (Final) |
Exit Exit |
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Achilleos S, Al-Ozairi E, Alahmad B, Garshick E, Neophytou AM, Bouhamra W, Yassin MF and Koutrakis P. Acute effects of air pollution on mortality:A 17-year analysis in Kuwait. Environment International 2019; 126:476-483. |
R835872 (2020) R835872C003 (Final) |
Exit Exit |
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Dedoussi IC, Allroggen F, Flanagan R, Hansen T, Taylor B, Barrett SR, Boyce JK. The co-pollutant cost of carbon emissions:an analysis of the US electric power generation sector. Environmental Research Letters 2019;14(9):094003. |
R835872 (2018) R835872 (2019) R835872 (2020) R835872C005 (Final) |
Exit Exit Exit |
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Mork D, Kioumourtzoglou MA, Weisskopf M, Coull BA, Wilson A. Heterogeneous Distributed Lag Models to Estimate Personalized Effects of Maternal Exposures to Air Pollution. ARXIV PREPRINT ARXIV 2019;13763. |
R835872 (Final) R835872C002 (Final) R839278 (2019) R839278 (Final) |
Exit |
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Henneman LR, Mickley LJ, Zigler CM. Air pollution accountability of energy transitions:the relative importance of point source emissions and wind fields in exposure changes. Environmental Research Letters 2019;14(11):115003. |
R835872 (2019) R835872C004 (Final) |
Exit Exit |
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Rice MB, Li W, Schwartz J, Di Q, Kloog I, Koutrakis P, Gold DR, Hallowell RW, Zhang C, O'Connor G, Washko GR. Ambient air pollution exposure and risk and progression of interstitial lung abnormalities:the Framingham Heart Study. Thorax 2019;74(11):1063-1069. |
R835872 (2019) R835872C003 (Final) |
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Rice MB, Li W, Wilker EH, Gold DR, Schwartz J, Zanobetti A, Koutrakis P, Kloog I, Washko GR, O'Connor GT, Mittleman MA. Association of outdoor temperature with lung function in a temperate climate. European Respiratory Journal 2019;53(1):1800612. |
R835872 (2018) R835872C003 (Final) |
Exit |
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Wei Y, Wang Y, Lin C-K, Yin K, Yang J, Shi L, Li L, Zanobetti A, Schwartz JD. Associations between seasonal temperature and dementia-associated hospitalizations in New England. Environment International 2019;126:228-233. |
R835872 (2019) R835872C003 (Final) |
Exit |
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Wu X, Braun D, Kioumourtzoglou MA, Choirat C, Di Q, Dominici F. Causal inference in the context of an error prone exposure:air pollution and mortality. The Annals of Applied Statistics 2019;13(1):520-547. |
R835872 (2018) R835872C004 (Final) |
Exit |
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Papadogeorgou G, Mealli F, Zigler CM. Causal inference with interfering units for cluster and population level treatment allocation programs. Biometrics 2019; 75(3):778-787. |
R835872 (2018) R835872 (2019) R835872C004 (Final) |
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Henneman LR, Choirat C, Ivey C, Cummiskey K, Zigler CM. Characterizing population exposure to coal emissions sources in the United States using the HyADS model. Atmospheric Environment 2019;203:271-280. |
R835872 (2018) R835872 (2019) R835872C004 (Final) |
Exit |
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Yitshak-Sade M, Blomberg AJ, Zanobetti A, Schwartz JD, Coull BA, Kloog I, Dominici F and Koutrakis P. County-level radon exposure and all-cause mortality risk among Medicare beneficiaries. Environ Int 2019; 130:104865. |
R835872 (2019) R835872C001 (Final) R835872C003 (Final) R835872C004 (Final) |
Exit |
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Goldman GT and Dominici F. Don't abandon evidence and process on air pollution policy. Science 2019; 363(6434):1398-1400. |
R835872C004 (Final) |
not available |
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Rhee J, Fabian MP, Ettinger de Cuba S, Coleman S, Sandel M, Lane KJ, Yitshak Sade M, Hart JE, Schwartz J, Kloog I, Laden F. Effects of maternal homelessness, supplemental nutrition programs, and prenatal PM2.5 on birthweight. International Journal of Environmental Research and Public Health 2019;16(21):4154. |
R835872 (2019) R836156 (2020) |
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Gilstrap LG, Dominici F, Wang Y, El-Sady MS, Singh A, Di Carli MF, Falk RH, Dorbala S. Epidemiology of cardiac amyloidosis-associated heart failure hospitalizations among fee-for-service medicare beneficiaries in the United States. Circulation Heart Failure 2019;12(6):e005407. |
R835872 (2018) R835872C004 (Final) |
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Harris MH, Gold DR, Rifas-Shiman SL, Melly SJ, Zanobetti A, Coull BA, Schwartz JD, Gryparis A, Kloog I, Koutrakis P, Bellinger DC, White RF, Sagiv SK and Oken E. Erratum:Prenatal and Childhood Traffic-Related Pollution Exposure and Childhood Cognition in the Project Viva Cohort (Massachusetts, USA). Environ Health Perspect 2019; 127(6):69001. |
R835872C003 (Final) |
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Shtein A, Kloog I, Schwartz J, Silibello C, Michelozzi P, Gariazzo C, Viegi G, Forastiere F, Karnieli A, Just AC, Stafoggia M. Estimating daily PM2.5 and PM10 over Italy using an ensemble model. Environmental Science & Technology 2019;54(1):120-128. |
R835872 (2019) R835872C001 (Final) |
Exit |
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Nethery RC, Mealli F, Dominici F. Estimating population average causal effects in the presence of non-overlap:the effect of natural gas compressor station exposure on cancer mortality. The Annals of Applied Statistics 2019;13(2):1242-1267. |
R835872 (2019) R835872C004 (Final) R836156 (2019) R836156 (2020) |
Exit |
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Yitshak-Sade M, Kloog I, Zanobetti A, Schwartz JD. Estimating the causal effect of annual PM2.5 exposure on mortality rates in the Northeastern and mid-Atlantic states. Environmental Epidemiology 2019;3(4):e052. |
R835872 (2019) R835872C003 (Final) |
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Gaskins AJ, Minguez-Alarcon L, Fong KC, Abdelmessih S, Coull BA, Chavarro JE, Schwartz J, Kloog I, Souter I, Hauser R, Laden F. Exposure to fine particulate matter and ovarian reserve among women from a fertility clinic. Epidemiology 2019;30(4):486-491. |
R835872 (2019) R835872C002 (Final) R835872C003 (Final) |
Exit |
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Dimanchev EG, Paltsev S, Yuan M, Rothenberg D, Tessum CW, Marshall JD, Selin NE. Health co-benefits of sub-national renewable energy policy in the US. Environmental Research Letters 2019;14(8):085012 |
R835872 (2018) R835872 (2019) R835872C005 (Final) R835873 (2019) R835873 (Final) |
Exit Exit |
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Antonelli J, Parmigiani G, Dominici F. High-dimensional confounding adjustment using continuous spike and slab priors. Bayesian Analysis 2019;14(3):805-828. |
R835872 (2019) R835872C004 (Final) R836156 (2020) |
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Rhee J, Dominici F, Zanobetti A, Schwartz J, Wang Y, Di Q, Balmes J, Christiani DC. Impact of long-term exposures to ambient PM2.5 and ozone on ARDS risk for older adults in the United States. Chest 2019; 156(1):71-79. |
R835872 (2018) R835872 (2019) R835872C003 (Final) R835872C004 (Final) |
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Gao X, Colicino E, Shen J, Kioumourtzoglou MA, Just AC, Nwanaji-Enwerem JC, Coull B, Lin X, Vokonas P, Zheng Y, Hou L. Impacts of air pollution, temperature, and relative humidity on leukocyte distribution:an epigenetic perspective. Environment International 2019;126:395-405. |
R835872 (2019) R835872C003 (Final) |
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Yazdi MD, Wang Y, Di Q, Zanobetti A, Schwartz J. Long-term exposure to PM2.5 and ozone and hospital admissions of Medicare participants in the Southeast USA. Environment International 2019;130:104879. |
R835872 (2019) R835872C003 (Final) |
Exit |
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Yitshak-Sade M, James P, Kloog I, Hart JE, Schwartz JD, Laden F, Lane KJ, Fabian MP, Fong KC and Zanobetti A. Neighborhood Greenness Attenuates the Adverse Effect of PM2.5 on Cardiovascular Mortality in Neighborhoods of Lower Socioeconomic Status. Int J Environ Res Public Health 2019; 16(5). |
R835872C003 (Final) |
Exit |
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Fleisch AF, Aris IM, Rifas-Shiman SL, Coull BA, Luttmann-Gibson H, Koutrakis P, Schwartz JD, Kloog I, Gold DR, Oken E. Prenatal exposure to traffic pollution and childhood body mass index trajectory. Frontiers in Endocrinology 2019;9:771. |
R835872 (2018) R835872 (2019) R835872C002 (Final) R835872C003 (Final) |
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Nyhan MM, Kloog I, Britter R, Ratti C and Koutrakis P. Quantifying population exposure to air pollution using individual mobility patterns inferred from mobile phone data. Journal of Exposure Science & Environmental Epidemiology 2019; 29(2):238-247. |
R835872C001 (Final) |
not available |
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Fong KC, Di Q, Kloog I, Laden F, Coull BA, Koutrakis P, Schwartz JD. Relative toxicities of major particulate matter constituents on birthweight in Massachusetts. Environmental Epidemiology 2019;3(3). |
R835872 (2019) R835872C002 (Final) R835872C003 (Final) |
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Li W, Dorans KS, Wilker EH, Rice MB, Ljungman PL, Schwartz JD, Coull BA, Koutrakis P, Gold DR, Keaney Jr JF, Vasan RS. Short-term exposure to ambient air pollution and circulating biomarkers of endothelial cell activation:The Framingham heart study. Environmental Research 2019;171:36-43. |
R835872 (2018) R835872C002 (Final) R835872C003 (Final) |
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Wright RJ, Coull BA. Small but mighty:prenatal ultrafine particle exposure linked to childhood asthma incidence. American Journal of Respiratory and Critical Care Medicine 2019;199(12):1448-1450. |
R835872 (2019) R835872C002 (Final) |
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Jhun I, Kim J, Cho B, Gold DR, Schwartz J, Coull BA, Zanobetti A, Rice MB, Mittleman MA, Garshick E, Vokonas P. Synthesis of Harvard Environmental Protection Agency (EPA) Center studies on traffic-related particulate pollution and cardiovascular outcomes in the Greater Boston Area. Journal of the Air & Waste Management Association 2019;69(8):900-917. |
R835872 (2019) R835872C002 (Final) R835872C004 (Final) |
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Heo S, Nori-Sarma A, Lee K, Benmarhnia T, Dominici F and Bell ML. The Use of a Quasi-Experimental Study on the Mortality Effect of a Heat Wave Warning System in Korea. Int J Environ Res Public Health 2019; 16(12). |
R835872C004 (Final) |
not available |
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Anderson GB, Barnes EA, Bell ML, Dominici F. The future of climate epidemiology:opportunities for advancing health research in the context of climate change. American Journal of Epidemiology 2019;188(5):866-872. |
R835872 (2019) R835872C004 (Final) R835871 (2019) R835871 (2020) |
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Gaskins AJ, Fong KC, Abu Awad Y, Di Q, Minguez-Alarcon L, Chavarro JE, Ford JB, Coull BA, Schwartz J, Kloog I, Souter I. Time-varying exposure to air pollution and outcomes of in vitro fertilization among couples from a fertility clinic. Environmental Health Perspectives 2019;127(7):077002. |
R835872 (2019) R835872C002 (Final) R835872C003 (Final) |
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Kioumourtzoglou M-A, Raz R, Wilson A, Fluss R, Nirel R, Broday DM, Yuval, Hacker MR, McElrath TF, Grotto I, Koutrakis P and Weisskopf MG. Traffic-related Air Pollution and Pregnancy Loss:. Epidemiology 2019; 30(1):4-10. |
R835872C003 (Final) |
Exit |
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Silvern RF, Jacob DJ, Mickley LJ, Sulprizio MP, Travis KR, Marais EA, Cohen RC, Laughner JL, Choi S, Joiner J, Lamsal LN. Using satellite observations of tropospheric NO_2 columns to infer long-term trends in US NOx emissions:the importance of accounting for the free tropospheric NO2 background. Atmospheric Chemistry and Physics 2019;19(13):8863-8878. |
R835872 (2019) R835872C001 (Final) |
Exit |
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Liu T, Mickley LJ, Marlier ME, DeFries RS, Khan MF, Latif MT, Karambelas A. Diagnosing spatial biases and uncertainties in global fire emissions inventories:Indonesia as regional case study. Remote Sensing of Environment 2020;237:111557. |
R835872 (2019) R835872 (2020) R835872C001 (Final) |
Exit |
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Kang CM, Liu M, Garshick E and Koutrakis P. Indoor particle alpha radioactivity origins in occupied homes. Aerosol Air Qual Res 2020; 20(6). |
R835872 (2020) R835872C001 (Final) R834798 (Final) |
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Li Y, Mickley LJ, Liu P, Kaplan JO. Trends and spatial shifts in lightning fires and smoke concentrations in response to 21st century climate over the national forests and parks of the western United States. ,em> Atmospheric Chemistry and Physics 2020;20(14):8827-38. |
R835872 (2020) R835872C001 (Final) R835875 (Final) |
Exit Exit |
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Gaffin JM, Hauptman M, Petty CR, Haktanir-Abul M, Gunnlaugsson S, Lai PS, Baxi SN, Permaul P, Sheehan WJ, Wolfson JM, Coull BA, Gold DR, Koutrakis P and Phipatanakul W. Differential Effect of School-Based Pollution Exposure in Children With Asthma Born Prematurely. Chest 2020; 158(4):1361-1363. |
R835872 (2020) R835872C002 (Final) R835872C003 (Final) R834798 (Final) |
Exit Exit |
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Cserbik D, Chen JC, McConnell R, Berhane K, Sowell ER, Schwartz J, Hackman DA, Kan E, Fan CC and Herting MM. Fine particulate matter exposure during childhood relates to hemispheric-specific differences in brain structure. Environ Int 2020; 143:105933. |
R835872 (2020) R835872C003 (Final) R835441 (Final) |
Exit Exit |
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Dolcini J, Kioumourtzoglou MA, Cayir A, Sanchez-Guerra M, Brennan KJ, Dereix AE, Coull BA, Spiro III A, Vokonas P, Schwartz J, Baccarelli AA. Age and mitochondrial DNA copy number influence the association between outdoor temperature and cognitive function:insights from the VA Normative Aging Study. Environmental Epidemiology 2020;4(4):e0108. |
R835872C002 (Final) |
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Woo SHL, Liu JC, Yue X, Mickley LJ and Bell ML. Air pollution from wildfires and human health vulnerability in Alaskan communities under climate change. Environmental Research Letters 2020; 15(9). |
R835872C001 (Final) |
Exit |
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Gaskins AJ, Minguez-Alarcon L, Williams PL, Chavarro JE, Schwartz JD, Kloog I, Souter I, Hauser R, Laden F and Team ES. Ambient air pollution and risk of pregnancy loss among women undergoing assisted reproduction. Environ Res 2020; 191:110201. |
R835872C003 (Final) |
Exit Exit |
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Papatheodorou S, Gold DR, Blomberg AJ, Hacker M, Wylie BJ, Requia WJ, Oken E, Fleisch AF, Schwartz JD and Koutrakis P. Ambient particle radioactivity and gestational diabetes:A cohort study of more than 1 million pregnant women in Massachusetts, USA. Science of The Total Environment 2020; 733. |
R835872C001 (Final) R835872C003 (Final) |
Exit |
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Vieira CLZ, Garshick E, Alvares D, Schwartz J, Huang S, Vokonas P, Gold DR and Koutrakis P. Association between ambient beta particle radioactivity and lower hemoglobin concentrations in a cohort of elderly men. Environment International 2020; 139. |
R835872C001 (Final) R835872C003 (Final) |
Exit |
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Wang C, Koutrakis P, Gao X, Baccarelli A and Schwartz J. Associations of annual ambient PM2.5 components with DNAm PhenoAge acceleration in elderly men:The Normative Aging Study. Environmental Pollution 2020; 258. |
R835872C003 (Final) |
Exit |
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Huang S, Garshick E, Weschler LB, Hong C, Li J, Li L, Qu F, Gao D, Zhou Y, Sundell J, Zhang Y and Koutrakis P. Home environmental and lifestyle factors associated with asthma, rhinitis and wheeze in children in Beijing, China. Environ Pollut 2020; 256:113426. |
R835872C001 (Final) R835872C003 (Final) |
Exit |
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Carone M, Dominici F and Sheppard L. In Pursuit of Evidence in Air Pollution Epidemiology:The Role of Causally Driven Data Science. Epidemiology 2020; 31(1):1-6. |
R835872C004 (Final) |
not available |
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Qiu X, Wei Y, Wang Y, Di Q, Sofer T, Awad YA, Schwartz J. Inverse probability weighted distributed lag effects of short-term exposure to PM2.5 and ozone on CVD hospitalizations in New England Medicare participants-Exploring the causal effects. Environmental Research 2020;182:109095. |
R835872 (2019) R835872C003 (Final) |
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Liao SX, Henneman L and Zigler C. Posterior predictive treatment assignment methods for causal inference in the context of time-varying treatments. Epidemiologic Methods 2020; 9(1):20190024. |
R835872C004 (Final) |
not available |
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Dedoussi IC, Eastham SD, Monier E, Barrett SR. Premature mortality related to United States cross-state air pollution. Nature 2020;578(7794):261-265. |
R835872 (2019) R835872C005 (Final) |
Exit |
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Rosofsky AS, Fabian MP, Ettinger de Cuba S, Sandel M, Coleman S, Levy JI, Coull BA, Hart JE and Zanobetti A. Prenatal Ambient Particulate Matter Exposure and Longitudinal Weight Growth Trajectories in Early Childhood. Int J Environ Res Public Health 2020; 17(4). |
R835872C002 (Final) R835872C003 (Final) |
Exit |
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Qiu X, Fong KC, Shi L, Papatheodorou S, Di Q, Just A, Kosheleva A, Messerlian C and Schwartz JD. Prenatal exposure to particulate air pollution and gestational age at delivery in Massachusetts neonates 2001–2015. Environmental Epidemiology 2020; 4(5). |
R835872C003 (Final) |
Exit |
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Hauptman M, Gaffin JM, Petty CR, Sheehan WJ, Lai PS, Coull B, Gold DR, Phipatanakul W. Proximity to major roadways and asthma symptoms in the School Inner-City Asthma Study. The Journal of Allergy and Clinical Immunology 2020;145(1):119-126. |
R835872C002 (Final) |
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Fong KC, Yitshak-Sade M, Lane KJ, Fabian MP, Kloog I, Schwartz JD, Coull BA, Koutrakis P, Hart JE, Laden F and Zanobetti A. Racial disparities in associations between neighborhood demographic polarization and birth weight. International Journal of Environmental Research and Public Health 2020; 17(9). |
R835872C002 (Final) R835872C003 (Final) |
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Al-Hemoud A, Al-Dousari A, Al-Dashti H, Petrov P, Al-Saleh A, Al-Khafaji S, Behbehani W, Li J and Koutrakis P. Sand and dust storm trajectories from Iraq Mesopotamian flood plain to Kuwait. Sci Total Environ 2020; 710:136291. |
R835872C001 (Final) |
not available |
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Huang S, Xiong J, Vieira CLZ, Blomberg AJ, Gold DR, Coull BA, Sarosiek K, Schwartz JD, Wolfson JM, Li J and Koutrakis P. Short-term exposure to ambient particle gamma radioactivity is associated with increased risk for all-cause non-accidental and cardiovascular mortality. Sci Total Environ 2020; 721:137793. |
R835872C001 (Final) R835872C002 (Final) R835872C003 (Final) |
Exit Exit |
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Huang S, Garshick E, Vieira CL, Grady ST, Schwartz JD, Coull BA, Hart JE, Laden F, Koutrakis P. Short-term exposures to particulate matter gamma radiation activities and biomarkers of systemic inflammation and endothelial activation in COPD patients. Environmental Research 2020;180:108841. |
R835872 (2019) R835872C001 (Final) R835872C002 (Final) R835872C003 (Final) |
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Alahmad B, Tomasso LP, Al-Hemoud A, James P and Koutrakis P. Spatial distribution of land surface temperatures in Kuwait: urban heat and cool islands. International Journal of Environmental Research and Public Health 2020; 17(9). |
R835872C001 (Final) |
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Requia WJ, Coull BA, Koutrakis P. Where air quality has been impacted by weather changes in the United States over the last 30 years?. Atmospheric Environment 2020;224:117360. |
R835872 (2019) R835872C001 (Final) |
Exit |
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Nethery RC, Mealli F, Sacks JD, Dominici F. Evaluation of the Health Impacts of the 1990 Clean Air Act Amendments Using Causal Inference and Machine Learning. Journal of the American Statistical Association 2020:1-12 |
R835872 (2020) R835872C004 (Final) |
Exit Exit |
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Li Y, Mickley LJ, Kaplan JO. Response of dust emissions in southwestern North America to 21st century trends in climate, CO 2 fertilization, and land use:implications for air quality. Atmospheric Chemistry and Physics 2021 ;21(1):57-68. |
R835872C001 (Final) R835875 (Final) |
Exit Exit |
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Vodonos A and Schwartz J. Estimation of excess mortality due to long-term exposure to PM2.5 in continental United States using a high-spatiotemporal resolution model. Environ Res 2021; 196:110904. |
R835872 (2020) R835872C003 (Final) |
Exit Exit |
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Weinberger KR, Wu X, Sun S, Spangler KR, Nori-Sarma A, Schwartz J, Requia W, Sabath BM, Braun D, Zanobetti A, Dominici F and Wellenius GA. Heat warnings, mortality, and hospital admissions among older adults in the United States. Environ Int 2021; 157:106834. |
R835872 (2020) R835872C003 (Final) |
Exit Exit |
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Shi L, Steenland K, Li H, Liu P, Zhang Y, Lyles RH, Requia WJ, Ilango SD, Chang HH, Wingo T, Weber RJ and Schwartz J. A national cohort study (2000-2018) of long-term air pollution exposure and incident dementia in older adults in the United States. Nat Commun 2021; 12(1):6754. |
R835872C003 (Final) |
Exit |
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Li L, Blomberg AJ, Lawrence J, Requia WJ, Wei Y, Liu M, Peralta AA, Koutrakis P. A spatiotemporal ensemble model to predict gross beta particulate radioactivity across the contiguous United States. Environment International 2021;156:106643. |
R835872C001 (Final) |
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Alahmad B, Al-Hemoud A, Kang CM, Almarri F, Kommula V, Wolfson JM, Bernstein AS, Garshick E, Schwartz J and Koutrakis P. A two-year assessment of particulate air pollution and sources in Kuwait. Environ Pollut 2021; 282:117016. |
R835872C001 (Final) |
not available |
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Lu W, Hackman DA and Schwartz J. Ambient air pollution associated with lower academic achievement among US children:A nationwide panel study of school districts. Environ Epidemiol 2021; 5(6):e174. |
R835872C003 (Final) |
Exit |
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Wei Y, Tiwari AS, Li L, Solanki B, Sarkar J, Mavalankar D and Schwartz J. Assessing mortality risk attributable to high ambient temperatures in Ahmedabad, 1987 to 2017. Environ Res 2021; 198:111232. |
R835872C003 (Final) |
Exit |
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Peralta AA, Schwartz J, Gold DR, Coull B and Koutrakis P. Associations between PM2.5 metal components and QT interval length in the Normative Aging Study. Environ Res 2021; 195:110827. |
R835872C002 (Final) R835872C003 (Final) |
Exit |
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Lee K, Small DS and Dominici F. Discovering Heterogeneous Exposure Effects Using Randomization Inference in Air Pollution Studies. J Am Stat Assoc 2021; 116(534):569-580. |
R835872C004 (Final) |
not available |
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Li J, Garshick E, Hart JE, Li L, Shi L, Al-Hemoud A, Huang S and Koutrakis P. Estimation of ambient PM2.5 in Iraq and Kuwait from 2001 to 2018 using machine learning and remote sensing. Environ Int 2021; 151:106445. |
R835872C001 (Final) |
Exit Exit |
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Henneman LRF, Shen H, Hogrefe C, Russell AG, Zigler CM. Four decades of United States mobile source pollutants:Spatial–temporal trends assessed by ground-based monitors, air quality models, and satellites. Environmental Science & Technology 2021;55:882–92 |
R835872C004 (Final) R835880 (Final) |
Exit Exit |
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Lopes Moreira TC, Huang S, Lawrence J, Martins MAG, Wolfson JM, Kang CM, Ferguson ST and Koutrakis P. Influence of road proximity on ambient concentrations of organic and elemental carbon fractions in coarse and fine particulate matter. J Air Waste Manag Assoc 2021; 71(3):283-284. |
R835872C001 (Final) |
not available |
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Qian Y, Li H, Rosenberg A, Li Q, Sarnat J, Papatheodorou S, Schwartz J, Liang D, Liu Y, Liu P and Shi L. Long-Term Exposure to Low-Level NO2 and Mortality among the Elderly Population in the Southeastern United States. Environ Health Perspect 2021; 129(12):127009. |
R835872C003 (Final) |
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Yazdi MD, Wang Y, Di Q, Requia WJ, Wei Y, Shi L, Sabath MB, Dominici F, Coull B, Evans JS, Koutrakis P and Schwartz JD. Long-term effect of exposure to lower concentrations of air pollution on mortality among US Medicare participants and vulnerable subgroups:a doubly-robust approach. The Lancet Planetary Health 2021; 5(10):e689-e697. |
R835872C003 (Final) |
Exit |
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Lawrence J, Martins M, Liu M and Koutrakis P. Measurement of the gross alpha activity of the fine fractions of road dust and near-roadway ambient particle matter. J Air Waste Manag Assoc 2021; 71(2):147-155. |
R835872C001 (Final) |
Exit Exit |
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deSouza P, Braun D, Parks RM, Schwartz J, Dominici F and Kioumourtzoglou M-A. Nationwide Study of Short-Term Exposure to Fine Particulate Matter and Cardiovascular Hospitalizations among Medicaid Enrollees. Epidemiology 2021; 32(1):6-13. |
R835872C003 (Final) |
Exit |
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Li L, Blomberg AJ, Stern RA, Kang CM, Papatheodorou S, Wei Y, Liu M, Peralta AA, Vieira CLZ and Koutrakis P. Predicting monthly community-level domestic radon concentrations in the greater Boston area with an ensemble learning model. Environmental Science & Technology 2021; 55(10):7157-7166. |
R835872C001 (Final) |
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Sordillo JE, Cardenas A, Qi C, Rifas-Shiman SL, Coull B, Luttmann-Gibson H, Schwartz J, Kloog I, Hivert MF, DeMeo DL, Baccarelli AA, Xu CJ, Gehring U, Vonk JM, Koppelman G, Oken E and Gold DR. Residential PM2.5 exposure and the nasal methylome in children. Environ Int 2021; 153:106505. |
R835872C002 (Final) |
not available |
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Gao X, Coull B, Lin X, Vokonas P, Spiro A, Hou L, Schwartz J and Baccarelli AA. Short-term air pollution, cognitive performance and nonsteroidal anti-inflammatory drug use in the Veterans Affairs Normative Aging Study. Nature Aging 2021; 1(5):430-437. |
R835872C002 (Final) R835872C003 (Final) |
Exit |
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Gao X, Koutrakis P, Coull B, Lin X, Vokonas P, Schwartz J and Baccarelli AA. Short-term exposure to PM2.5 components and renal health:Findings from the Veterans Affairs Normative Aging Study. J Hazard Mater 2021; 420:126557. |
R835872C002 (Final) R835872C003 (Final) |
Exit Exit |
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Shi L, Rosenberg A, Wang Y, Liu P, Danesh Yazdi M, Requia W, Steenland K, Chang H, Sarnat JA, Wang W, Zhang K, Zhao J and Schwartz J. Low-Concentration Air Pollution and Mortality in American Older Adults:A National Cohort Analysis (2001-2017). Environ Sci Technol 2022; 56(11):7194-7202. |
R835872 (2020) R835872C003 (Final) |
Exit Exit |
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Atkinson W, Eastham SD, Chen Y-HH, Morris J, Paltsev S, Schlosser CA and Selin NE. A tool for air pollution scenarios (TAPS v1.0) to enable global, long-term, and flexible study of climate and air quality policies. Geoscientific Model Development 2022; 15:7767-7789. |
R835872C005 (Final) |
Exit |
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Wei Y, Qiu X, Sabath MB, Yazdi MD, Yin K, Li L, Peralta AA, Wang C, Koutrakis P, Zanobetti A, Dominici F and Schwartz JD. Air Pollutants and Asthma Hospitalization in the Medicaid Population. Am J Respir Crit Care Med 2022; 205(9):1075-1083. |
R835872C003 (Final) |
Exit |
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Qiu X, Danesh-Yazdi M, Weisskopf M, Kosheleva A, Spiro AS, Wang C, Coull BA, Koutrakis P and Schwartz JD. Associations between Air Pollution and Psychiatric Symptoms in The Normative Aging Study. Environ Res Lett 2022; 17(3). |
R835872C003 (Final) |
Exit |
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Jin T, Di Q, Requia WJ, Danesh Yazdi M, Castro E, Ma T, Wang Y, Zhang H, Shi L and Schwartz J. Associations between long-term air pollution exposure and the incidence of cardiovascular diseases among American older adults. Environ Int 2022; 170:107594. |
R835872C003 (Final) |
Exit |
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Tracy SM, Vieira CLZ, Garshick E, Wang VA, Alahmad B, Eid R, Schwartz J, Schiff JE, Vokonas P and Koutrakis P. Associations between solar and geomagnetic activity and peripheral white blood cells in the Normative Aging Study. Environ Res 2022; 204(Pt B):112066. |
R835872C001 (Final) R835872C003 (Final) |
Exit |
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Peng RD, Liu JC, McCormack MC, Mickley LJ and Bell ML. Estimating the health effects of environmental mixtures using principal stratification. Stat Med 2022; 41(10):1815-1828. |
R835872C001 (Final) |
not available |
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Li J, Kang CM, Wolfson JM, Alahmad B, Al-Hemoud A, Garshick E and Koutrakis P. Estimation of fine particulate matter in an arid area from visibility based on machine learning. J Expo Sci Environ Epidemiol 2022; 32(6):926-931. |
R835872C001 (Final) |
not available |
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Leung M, Weisskopf MG, Laden F, Coull BA, Modest AM, Hacker MR, Wylie BJ, Wei Y, Schwartz J and Papatheodorou S. Exposure to PM2.5 during Pregnancy and Fetal Growth in Eastern Massachusetts, USA. Environ Health Perspect 2022; 130(1):17004. |
R835872C002 (Final) R835872C003 (Final) |
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Vieira CL, Chen K, Garshick E, Liu M, Vokonas P, Ljungman P, Schwartz J, Koutrakis P. Geomagnetic disturbances reduce heart rate variability in the Normative Aging Study. Science of the Total Environment 2022;839:156235. |
R835872C001 (Final) R835872C003 (Final) |
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Li H, Deng W, Small R, Schwartz J, Liu J and Shi L. Health effects of air pollutant mixtures on overall mortality among the elderly population using Bayesian kernel machine regression (BKMR). Chemosphere 2022; 286(Pt 1):131566. |
R835872C003 (Final) |
Exit |
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Requia WJ, Papatheodorou S, Koutrakis P, Mukherjee R and Roig HL. Increased preterm birth following maternal wildfire smoke exposure in Brazil. Int J Hyg Environ Health 2022; 240:113901. |
R835872C003 (Final) |
Exit |
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Liao NS, Van Den Eeden SK, Sidney S, Deosaransingh K, Schwartz J, Uong SP and Alexeeff SE. Joint associations between neighborhood walkability, greenness, and particulate air pollution on cardiovascular mortality among adults with a history of stroke or acute myocardial infarction. Environ Epidemiol 2022; 6(2):e200. |
R835872C003 (Final) |
Exit |
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Li J, Wang Y, Steenland K, Liu P, van Donkelaar A, Martin RV, Chang HH, Caudle WM, Schwartz J, Koutrakis P and Shi L. Long-term effects of PM2.5 components on incident dementia in the northeastern United States. Innovation (Camb) 2022; 3(2):100208. |
R835872C003 (Final) |
Exit |
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Yuan M, Barron AR, Selin NE, Picciano PD, Lucy E Metz, Reilly JM and Jacoby HD. Meeting U.S. greenhouse gas emissions goals with the international air pollution provision of the clean air act. Environ Res Lett 2022; 17. |
R835872C005 (Final) |
not available |
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Vanoli J, Coull BA, Ettinger de Cuba S, Fabian PM, Carnes F, Massaro MA, Poblacion A, Bellocco R, Kloog I, Schwartz J, Laden F and Zanobetti A. Postnatal exposure to PM2.5 and weight trajectories in early childhood. Environ Epidemiol 2022; 6(1):e181. |
R835872C002 (Final) R835872C003 (Final) |
Exit |
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Requia WJ, Kill E, Papatheodorou S, Koutrakis P and Schwartz JD. Prenatal exposure to wildfire-related air pollution and birth defects in Brazil. J Expo Sci Environ Epidemiol 2022; 32(4):596-603. |
R835872C003 (Final) |
Exit |
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Vohra K, Marais EA, Bloss WJ, Schwartz J, Mickley LJ, Damme MV, Clarisse L and Coheur P-F. Rapid rise in premature mortality due to anthropogenic air pollution in fast-growing tropical cities from 2005 to 2018. Science Advances 2022; 8. |
R835872C001 (Final) R835872C003 (Final) |
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Qiu X, Wei Y, Weisskopf M, Spiro A, Shi L, Castro E, Coull B, Koutrakis P and Schwartz J. Air pollution, climate conditions and risk of hospital admissions for psychotic disorders in U.S. residents. Environ Res 2023; 216(Pt 2):114636. |
R835872C003 (Final) R836156 (Final) |
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Wang VA, Koutrakis P, Li L, Liu M, Vieira CLZ, Coull BA, Maher EF, Kang CM and Garshick E. Particle radioactivity from radon decay products and reduced pulmonary function among chronic obstructive pulmonary disease patients. Environ Res 2023; 216(Pt 1):114492. |
R835872C001 (Final) R834798 (Final) |
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Lee HJ, Bell ML and Koutrakis P. Drought and ozone air quality in California:Identifying susceptible regions in the preparedness of future drought. Environ Res 2023; 216(Pt 1):114461. |
R835872C001 (Final) |
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Shi L, Zhu Q, Wang Y, Hao H, Zhang H, Schwartz J, Amini H, van Donkelaar A, Martin RV, Steenland K, Sarnat JA, Caudle WM, Ma T, Li H, Chang HH, Liu JZ, Wingo T, Mao X, Russell AG, Weber RJ and Liu P. Incident dementia and long-term exposure to constituents of fine particle air pollution:A national cohort study in the United States. Proc Natl Acad Sci U S A 2023; 120(1):e2211282119. |
R835872C003 (Final) |
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Feng Y, Wei Y, Coull BA and Schwartz JD. Measurement error correction for ambient PM(2.5) exposure using stratified regression calibration: Effects on all-cause mortality. Environ Res 2023; 216(Pt 4):114792. |
R835872C003 (Final) |
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Freese LM, Chossière GP, Eastham SD, Jenn A and Selin NE. Nuclear power generation phase-outs redistribute US air quality and climate-related mortality risk. Nature Energy 2023; 8:492-503. |
R835872C005 (Final) |
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Wang VA, Leung M, Li L, Modest AM, Schwartz J, Coull BA, Hacker MR, Wylie BJ, Koutrakis P and Papatheodorou S. Prenatal exposure to ambient particle radioactivity and fetal growth in Eastern Massachusetts. Air Quality, Atmosphere & Health 2023; 16:805-815. |
R835872C001 (Final) R835872C003 (Final) |
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Eastham SD, Monier E, Rothenberg D, Paltsev S and Selin NE. Rapid Estimation of Climate-Air Quality Interactions in Integrated Assessment Using a Response Surface Model. ACS Environ Au 2023; 3(3):153-163. |
R835872C005 (Final) |
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Peralta AA, Gold DR, Yazdi MD, Wei Y and Schwartz J. The role of short-term air pollution and temperature on arterial stiffness in a longitudinal closed cohort of elderly individuals. Environ Res 2023; 216(Pt 2):114597. |
R835872C003 (Final) |
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Di Q, Rowland S, Koutrakis P, Schwartz J. (2017) A hybrid model for spatially and temporally resolved ozone exposures in the continental United States. J Air and Waste Management Association, 67.1:39-52. |
R835872C003 (2016) |
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Wang, Y., Shi, L.H., Lee, M., Liu, P.F., Di, Q., Zanobetti, A., and Schwartz, J. (2017). Long-term Exposure to PM2.5 and Mortality Among Older Adults in the Southeastern US. Epidemiology 28, 207-214. |
R835872C003 (2016) |
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Antonelli, J., Zigler, C., and Dominici, F. (2017). Guided Bayesian Imputation to Adjust for Confounding when Combining Heterogeneous Data Sources in Comparative Effectiveness Research. Biostatistics 1–16 doi:10.1093/biostatistics/kxx003, 1-16. |
R835872C005 (2016) |
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Tang C, Coull B, Schwartz J, Lyapustin A, Di Q, Koutrakis P (2016) Trends and Spatial Patterns of Fine Resolution AOD-Derived PM2.5 Emissions in the Northeast United States from 2002 to 2013. Journal of the Air Waste & Management Association. In press. http://dx.doi.org.ezp-prod1.hul.harvard.edu/10.1080/10962247.2016.1218393. |
R835872C001 (2016) R835872C001 (Final) |
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Di Q, Kloog I, Koutrakis P, Lyapustin A, Wang Y, Schwartz J (2016) Assessing PM2.5 exposures with high spatiotemporal resolution across the continental United States. Environmental Science & Technology, 50(9):4712-4721. |
R835872C001 (2016) |
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Henneman LR, Choirat C, Zigler CM. Accountability assessment of health improvements in the United States associated with reduced coal emissions between 2005 and 2012. Epidemiology,/em> 2019;30(4):477-485.. |
R835872 (2019) R835872C004 (Final) |
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Klompmaker JO, Hart JE, James P, Sabath MB, Wu X, Zanobetti A, Dominici F and Laden F. Air pollution and cardiovascular disease hospitalization-Are associations modified by greenness, temperature and humidity? Environ Int 2021; 156:106715. |
R835872C003 (Final) |
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Moody EC, Cantoral A, Tamayo-Ortiz M, Pizano-Zárate ML, Schnaas L, Kloog I, Oken E, Coull B, Baccarelli A, Téllez-Rojo MM, Wright RO. Association of prenatal and perinatal exposures to particulate matter with changes in hemoglobin A1c levels in children aged 4 to 6 years. JAMA Network Open 2019;2(12):e1917643. |
R835872C002 (Final) |
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Peralta AA, Schwartz J, Gold DR, Coull B, Koutrakis P. Associations between acute and long-term exposure to PM2.5 components and temperature with QT interval length in the VA Normative Aging Study. European Journal of Preventive Cardiology 2021. |
R835872C002 (Final) R835872C003 (Final) |
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Henneman LR, Dedoussi IC, Casey JA, Choirat C, Barrett SR, Zigler CM. Comparisons of simple and complex methods for quantifying exposure to individual point source air pollution emissions. Journal of Exposure Science & Environmental Epidemiology 2020:1-10. |
R835872 (2019) R835872C004 (Final) |
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Coull BA, Lee S, McGee G, Manjourides J, Mittleman MA and Wellenius GA. Corrections for measurement error due to delayed onset of illness for case-crossover designs. Biometrics 2019. |
R835872 (2019) R835872C002 (Final) |
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Lee K, Small DS, Dominici F. Discovering effect modification and randomization inference in air pollution studies. arXiv preprint arXiv:1802.06710. 2018 Feb 19. |
R835872 (2018) |
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Huang S, Koutrakis P, Grady ST, Vieira CLZ, Schwartz JD, Coull BA, Hart JE, Laden F, Zhang JJ and Garshick E. Effects of particulate matter gamma radiation on oxidative stress biomarkers in COPD patients. J Expo Sci Environ Epidemiol 2020. |
R835872C001 (Final) R835872C002 (Final) R835872C003 (Final) |
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Mukharesh L, Greco KF, Banzon T, Koutrakis P, Li L, Hauptman M, Phipatanakul W and Gaffin JM. Environmental radon and childhood asthma. 2022; 57(12):3165-3168. |
R835872C001 (Final) R835872C003 (Final) |
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Kim C, Henneman LR, Choirat C, Zigler CM. Health effects of power plant emissions through ambient air quality. Journal of the Royal Statistical Society:Series A. 2020. [Epub ahead of print]. |
R835872 (2019) R835872C004 (Final) |
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Henneman LRF, Rasel MM, Choirat C, Anenberg SC and Zigler C. Inequitable Exposures to U.S. Coal Power Plant-Related PM2.5:22 Years and Counting. Environ Health Perspect 2023; 131(3):37005. |
R835872C004 (Final) |
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Di Q, Rowland S, Koutrakis P, Schwartz J (2017) A hybrid model for spatially and temporally resolved ozone exposures in the continental United States. Journal of the Air & Waste Management Association, 67(1):39-52. |
R835872C001 (2016) R835872C001 (Final) |
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Tang C, Coull B, Schwartz J, Lyapustin A, Di Q, Koutrakis P (2016) Developing Particle Emission Inventories Using Remote Sensing (PEIRS). Journal of the Air Waste & Management Association. In press. http://dx.doi.org.ezp-prod1.hul.harvard.edu/10.1080/10962247.2016.1214630. |
R835872C001 (2016) |
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Wilson A, Hsu HH, Chiu YH, Wright RO, Wright RJ, Coull BA. Kernel machine and distributed lag models for assessing windows of susceptibility to environmental mixtures in children’s health studies. The Annals of Applied Statistics 2022;16(2):1090. |
R835872C002 (Final) |
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Cowell WJ, Brunst KJ, Malin AJ, Coull BA, Gennings C, Kloog I, Lipton L, Wright RO, Enlow MB, Wright RJ. Prenatal exposure to PM2.5 and cardiac vagal tone during infancy:findings from a multiethnic birth cohort. Environmental Health Perspectives. 2019;127(10):107007. |
R835872C002 (Final) R835872C003 (Final) |
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Gao X, Koutrakis P, Blomberg AJ, Coull B, Vokonas P, Schwartz J, Baccarelli AA. Short-term ambient particle radioactivity level and renal function in older men:Insight from the Normative Aging Study. Environment International 2019;131:105018. |
R835872 (2019) R835872C001 (Final) R835872C003 (Final) |
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Chu MT, Ettinger de Cuba S, Fabian MP, Lane KJ, James-Todd T, Williams DR, Coull BA, Carnes F, Massaro M, Levy JI, Laden F, Sandel M, Adamkiewicz G and Zanobetti A. The immigrant birthweight paradox in an urban cohort:Role of immigrant enclaves and ambient air pollution. J Expo Sci Environ Epidemiol 2022. |
R835872C003 (Final) |
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Huang S, Taddei P, Lawrence J, Martins MAG, Li J and Koutrakis P. Trace element mass fractions in road dust as a function of distance from road. Journal of the Air & Waste Management Association 2020. |
R835872C001 (Final) |
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Liao SX, Zigler CM. Uncertainty in the design stage of two‐stage Bayesian propensity score analysis. Statistics in Medicine 2020. [Epub ahead of print]. doi:10.1002/sim.8486. |
R835872 (2019) R835872C004 (Final) |
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Liu JZ. Variable Selection with Rigorous Uncertainty Quantication using Deep Bayesian Neural Networks:Posterior Concentration and Bernstein-von Mises Phenomenon. arXiv 2019:1912.01189v01181. |
R835872C002 (Final) |
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Supplemental Keywords:
particles, pollutant mixtures, pollution trends, public policy, data fusion, climate change, regional pollution, multi-resolution spatial analysis, source emissions, local pollution control strategies, wavelet analysis, particles, particulate matter, pollutant mixtures, regional pollution, risk analysis, causal modeling, accountability assessment, power-generating sector, intervention evaluation, source-receptor mapping, PM2.5, ozone, adjoint method, air quality, greenhouse gas, computable general equilibrium, mercury, polycyclic aromatic hydrocarbons, PAHsRelevant Websites:
Harvard/MIT Air, Climate & Energy Center Exit
MIT Joint Program on the Science and Policy of Global Change Exit
Progress and Final Reports:
Original Abstract Subprojects under this Center: (EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
R835872C001 Project 1: Regional Air Pollution Mixtures: The Past and Future Impacts of Emission Controls and Climate Change on Air Quality and Health
R835872C002 Project 2: Air Pollutant Mixtures in Eastern Massachusetts: Spatial Multi-resolution Analysis of Trends, Effects of Modifiable Factors, Climate and Particle-induced Mortality
R835872C003 Project 3: Causal Estimates of Effects of Regional and National Pollution Mixtures on Health: Providing Tools for Policy Makers
R835872C004 A Causal Inference Framework to Support Policy Decisions by Evaluating the Effectiveness of Past Air Pollution Control Strategies for the Entire United States
R835872C005 Project 5: Projecting and Quantifying Future Changes in Socioeconomic Drivers of Air Pollution and its Health-Related Impacts
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.
Project Research Results
- Final Report
- 2021 Progress Report
- 2020 Progress Report
- 2019 Progress Report
- 2018 Progress Report
- 2016 Progress Report
- Original Abstract
419 journal articles for this center