Grantee Research Project Results
Publications Details for Grant Number R834693
Risk Assessment for Manufactured Nanoparticles Used in Consumer Products (RAMNUC)
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| Reference Type | Citation | Progress Report Year | Document Sources |
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| Abstract | Therkorn J, Calderon L, Cartledge B, Thomas N, Majestic B, Maineles G. Inactivation of pure bacterial biofilms by impaction of aerosolized consumer products containing nanoparticulate metals. ENVIRONMENTAL SCIENCE: NANO 2018;5:544-555 |
R834693 (Final) |
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| Abstract | Nazarenko, Y., Zhen, H., Han, T., Lioy, P. and Mainelis, G. Nanomaterial inhalation exposure from nanotechnology-based cosmetic powders:a quantitative assessment. Nanoparticle Research. 2012, 14:1229-1243. |
R834693 (2015) |
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| Journal Article | Calderon L, Han T, McGilvery CM, Yang L, Subramaniam P, Lee K-B, Schwander S, Tetley TS, Georgopoulos P, Ryan M, Porter AE, Smith R, Chung KF, Lioy PJ, Zhang J, Mainelis G. Release of airborne particles and Ag and Zn compounds from nanotechnology-enabled consumer sprays: Implications for inhalation exposure. Atmospheric Environment. 2017;155:85-96. |
R834693 (2015) R834693 (Final) |
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| Journal Article | Chen S, Theodorou IG, Goode AE, Gow A, Schwander S, Zhang JJ, Chung KF, Tetley TD, Shaffer MS, Ryan MP, Porter AE. High-resolution analytical electron microscopy reveals cell culture media-induced changes to the chemistry of silver nanowires. Environmental Science & Technology 2013;47(23):13813-13821. |
R834693 (2014) R834693 (2015) R834693 (Final) |
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| Journal Article | Chen S, Goode AE, Sweeney S, Theodorou IG, Thorley AJ, Ruenraroengsak P, Chang Y, Gow A, Schwander S, Skepper J, Zhang JJ, Shaffer MS, Chung KF, Tetley TD, Ryan MP, Porter AE. Sulfidation of silver nanowires inside human alveolar epithelial cells: a potential detoxification mechanism. Nanoscale 2013;5(20):9839-9847. |
R834693 (2014) R834693 (2015) R834693 (Final) |
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| Journal Article | Chen S, Goode AE, Skepper JN, Thorley AJ, Seiffert JM, Chung KF, Tetley TD, Shaffer MS, Ryan MP, Porter AE. Avoiding artefacts during electron microscopy of silver nanomaterials exposed to biological environments. Journal of Microscopy 2015;261(2):157-166. |
R834693 (2015) R834693 (Final) |
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| Journal Article | Cole TB, Fisher JC, Burbacher TM, Costa LG, Furlong CE. Neurobehavioral assessment of mice following repeated postnatal exposure to chlorpyrifos-oxon. Neurotoxicology and Teratology. 2012;34(3):311-22. |
R834514 (Final) R834514C004 (Final) R834693 (2015) |
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| Journal Article | Cole TB, Fisher JC, Burbacher TM, Costa LG, Furlong CE. Neurobehavioral assessment of mice following repeated postnatal exposure to chlorpyrifos-oxon. Neurotoxicology and Teratology 2012;34(3):311-322. |
R834514 (2011) R834514 (2012) R834514 (2013) R834693 (Final) |
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| Journal Article | Leo BF, Chen S, Kyo Y, Herpoldt KL, Terrill NJ, Dunlop IE, McPhail DS, Shaffer MS, Schwander S, Gow A, Zhang J, Chung KF, Tetley TD, Porter AE, Ryan MP. The stability of silver nanoparticles in a model of pulmonary surfactant. Environmental Science & Technology 2013;47(19):11232-11240. |
R834693 (2014) R834693 (2015) R834693 (Final) |
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| Journal Article | Lopez-Heras M, Theodorou IG, Leo BF, Ryan MP, Porter AE. Towards understanding the antibacterial activity of Ag nanoparticles: electron microscopy in the analysis of the materials-biology interface in the lung. Environmental Science: Nano 2015;2(4):312-326. |
R834693 (2015) R834693 (Final) |
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| Journal Article | Mukherjee D, Leo BF, Royce SF, Porter AE, Ryan MP, Schwander S, Chung KF, Tetley TD, Zhang J, Georgopoulos PG. Modeling physiochemical interactions affecting in vitro cellular dosimetry of engineered nanomaterials: application to nanosilver. Journal of Nanoparticle Research 2014;16(10):2616 (29 pp.). |
R834693 (2015) R834693 (Final) |
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| Journal Article | Nazarenko Y, Zhen H, Han T, Lioy PJ, Mainelis G. Potential for inhalation exposure to engineered nanoparticles from nanotechnology-based cosmetic powders. Environmental Health Perspectives 2012;120(6):885-892. |
R834693 (2011) R834693 (2012) R834693 (2013) R834693 (2014) R834693 (2015) R834693 (Final) |
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| Journal Article | Nazarenko Y, Zhen H, Han T, Lioy PJ, Mainelis G. Nanomaterial inhalation exposure from nanotechnology-based cosmetic powders: a quantitative assessment. Journal of Nanoparticle Research 2012;14(11):1229 (14 pp.). |
R834693 (2014) R834693 (2015) R834693 (Final) |
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| Journal Article | Nazarenko Y, Lioy PJ, Mainelis G. Quantitative assessment of inhalation exposure and deposited dose of aerosol from nanotechnology-based consumer sprays. Environmental Science: Nano 2014;1(2):161-171. |
R834693 (2013) R834693 (2014) R834693 (2015) R834693 (Final) |
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| Journal Article | Royce SG, Mukherjee D, Cai T, Xu SS, Alexander JA, Mi Z, Calderon L, Mainelis G, Lee K, Lioy PJ, Tetley TD, Chung KF, Zhang J, Georgopoulos PG. Modeling population exposures to silver nanoparticles present in consumer products. Journal of Nanoparticle Research 2014;16(11):2724. |
R834693 (2013) R834693 (2014) R834693 (2015) R834693 (Final) |
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| Journal Article | Sarkar S, Zhang L, Subramaniam P, Lee KB, Garfunkel E, Strickland PA, Mainelis G, Lioy PJ, Tetley TD, Chung KF, Zhang J, Ryan M, Porter A, Schwander S. Variability in bioreactivity linked to changes in size and zeta potential of diesel exhaust particles in human immune cells. PLoS ONE 2014;9(5):e97304 (12 pp.). |
R834693 (2014) R834693 (2015) R834693 (Final) |
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| Journal Article | Seiffert J, Hussain F, Wiegman C, Li F, Bey L, Baker W, Porter A, Ryan MP, Chang Y, Gow A, Zhang J, Zhu J, Tetley TD, Chung KF. Pulmonary toxicity of instilled silver nanoparticles: influence of size, coating and rat strain. PLOS ONE 2015;10(3):e0119726 (17 pp.). |
R834693 (2013) R834693 (2014) R834693 (2015) R834693 (Final) |
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| Journal Article | Seiffert J, Buckley A, Leo B, Martin NG, Zhu J, Dai R, Hussain F, Guo C, Warren J, Hodgson A, Gong J, Ryan MP, Zhang JJ, Porter A, Tetley TD, Gow A, Smith R, Chung KF. Pulmonary effects of inhalation of spark-generated silver nanoparticles in Brown-Norway and Sprague-Dawley rats. Respiratory Research 2016;17(1):85 (15 pp.). |
R834693 (2014) R834693 (2015) R834693 (Final) |
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| Journal Article | Subramaniam P, Lee SJ, Shah S, Patel S, Starovoytov V, Lee K-B. Generation of a library of non-toxic quantum dots for cellular imaging and siRNA delivery. Advanced Materials 2012;24(29):4014-4019. |
R834693 (2011) R834693 (2012) R834693 (2013) R834693 (2014) R834693 (2015) R834693 (Final) |
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| Journal Article | Theodorou IG, Ryan MP, Tetley TD, Porter AE. Inhalation of silver nanomaterials--seeing the risks. International Journal of Molecular Sciences 2014;15(12):23936-23974. |
R834693 (2015) R834693 (Final) |
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| Journal Article | Theodorou IG, Botelho D, Schwander S, Zhang J, Chung KF, Tetley TD, Shaffer MS, Gow A, Ryan MP, Porter AE. Static and dynamic microscopy of the chemical stability and aggregation state of silver nanowires in components of murine pulmonary surfactant. Environmental Science & Technology 2015; 49(13):8048-8056. |
R834693 (2015) R834693 (Final) |
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| Journal Article | Zhang J, Nazarenko Y, Zhang L, Calderon L, Lee KB, Garfunkel E, Schwander S, Tetley TD, Chung KF, Porter AE, Ryan M, Kipen H, Lioy PJ, Mainelis G. Impacts of a nanosized ceria additive on diesel engine emissions of particulate and gaseous pollutants. Environmental Science & Technology 2013;47(22):13077-13085. |
R834693 (2013) R834693 (2014) R834693 (2015) R834693 (Final) |
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| Journal Article | Zhang J, Lee K-B, He L, Seiffert J, Subramaniam P, Yang L, Chen S, Maguire P, Mainelis G, Schwander S, Tetley T, Porter, A, Ryan M, Shaffer M, Hu S, Gong J, Chung KF. Effects of a nanoceria fuel additive on physicochemical properties of diesel exhaust particles. Environmental Science: Processes and Impacts 2016;18(10):1333-1342. |
R834693 (2015) R834693 (Final) |
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| Journal Article | Sarkar S, Song Y, Sarkar S, Kipen HM, Laumbach RJ, Zhang J, Strickland PA, Gardner CR, Schwander S. Suppression of the NF-κB pathway by diesel exhaust particles impairs human antimycobacterial immunity. The Journal of Immunology. 2012;188(6):2778-93 |
R834693 (2015) |
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| Journal Article | Mukherjee D, Royce SG, Sarkar S, Thorley A, Schwander S, Ryan MP, Porter AE, Chung KF, Tetley TD, Zhang J, Georgopoulos PG. Modeling in vitro cellular responses to silver nanoparticles. Journal of Toxicology 2014;2014:852890 (13 pp.). |
R834693 (2015) R834693 (Final) |
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| Journal Article | Mukherjee D, Porter, A, Ryan M, Schwander S, Chung KF, Tetley T, Zhang J, Georgopoulos P. Modeling in vivo interactions of engineered nanoparticles in the pulmonary alveolar lining fluid. Nanomaterials 2015;5(3):1223-1249. |
R834693 (2015) R834693 (Final) |
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| Journal Article | Theodorou IG, Ruenraroengsak P, Gow A, Schwander S, Zhang JJ, Chung KF, Tetley TD, Ryan MP, Porter AE. Effect of pulmonary surfactant on the dissolution, stability and uptake of zinc oxide nanowires by human respiratory epithelial cells. Nanotoxicology 2016;10(9):1351-1362. |
R834693 (2015) R834693 (Final) |
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| Journal Article | Chung KF, Seiffert J, Chen S, Theodorou I, Goode A, Leo BF, McGilvery C, Hussain F, Wiegman C, Rossios C, Zhu J, Gong J, Tariq F, Yufit V, Monteith A, Hashimoto T, Skepper J, Ryan M, Zhang J, Tetley T, Porter A. Inactivation, clearance and functional effects of lung-instilled short and long silver nanowires in rat. ACS Nano 2017;11(3):2652-2664. |
R834693 (2015) R834693 (Final) |
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| Journal Article | Mukherjee D, Botelho D, Gow A, Zhang J, Georgopoulos PG. Computational multiscale toxicodynamic modeling of silver and carbon nanoparticle effects on mouse lung function. 2013, PLOS One, 8(12):e80917. |
R834693 (2015) |
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| Journal Article | Sweeney S, Theodorou IG, Zambianchi M, Chen S, Gow A, Schwander S, Zhang J, Chung KF, Shaffer MS, Ryan MP, Porter AE, Tetley TD. Silver nanowire interactions with primary human alveolar type-II epithelial cell secretions:contrasting bioreactivity with human alveolar type-I and type-II epithelial cells. Nanoscale, 2015 Jun 4;7(23):10398-409. |
R834693 (2015) |
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| Presentation | Calderon L, Zhen H, Wang Z, Buckley B, Bennett JW, Lioy PJ, Mainelis G. Investigation of bioaerosol contamination in New Jersey homes affected by Hurricane Sandy. Presented at the 32nd Annual Meeting of the American Association for Aerosol Research (AAAR), Portland, OR, September 30-October 4, 2013. |
R834693 (2014) R834693 (2015) R834693 (Final) |
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| Presentation | Chung KF, Mainelis G, Mukherjee D. RAMNUC Center presentation. Presented at the National Environmental Research Center (NERC) Grantee Meeting, Imperial College, London, England, UK, July 1-2, 2013. |
R834693 (2013) R834693 (2015) R834693 (Final) |
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| Presentation | Chung KF, Mainelis G, Calderon L, Baker W, Tetley T, Schwander S, Lioy PJ, Georgopoulos P, Lee K-B, Garfunkel E, Ryan MP, Porter A, Sankar S, Seiffert J, Smith R, Zhang J. Characterization and cellular effects of nanotechnology-enabled consumer sprays containing silver and zinc nanoparticles. Presented at Nano2014: 9th International Conference on the Environmental Effects of Nanoparticles and Nanomaterials, Columbia, SC, September 11, 2014. |
R834693 (2014) R834693 (2015) R834693 (Final) |
not available |
| Presentation | Mainelis G, Nazarenko Y, Calderon L, Zhang L, Lioy P, Chung KF, Zhang J. Effect of nanosized CeO2 catalyst on particulate and gaseous components of diesel emissions. Presented at the Society of Environmental Toxicology and Chemistry (SETAC) North America 33rd Annual Meeting, Long Beach, CA, November 11-15, 2012. |
R834693 (2013) R834693 (2015) R834693 (Final) |
not available |
| Presentation | Mainelis G, Calderon L, Nazarenko Y, Lee KB, Garfunkel E, Schwander S, Tetley T, Lioy P, Chung KF, Zhang J. Potential consumer exposure to airborne Ag and Zn nanoparticles due to the use of nanotechnology-enabled consumer sprays. Presented at the Society of Environmental Toxicology and Chemistry (SETAC) North America 33rd Annual Meeting, Long Beach, CA, November 11-15, 2012. |
R834693 (2013) R834693 (2015) R834693 (Final) |
not available |
| Presentation | Mainelis G, Nazarenko Y, Calderón L, Zhang L, Lioy P, Chung KF, Zhang J. Effect of nanosized CeO2 catalyst on particulate and gaseous components of diesel emissions. Poster presented at the National Nanotechnology Initiative Workshop: Stakeholder Perspectives on the Perception, Assessment, and Management of the Potential Risks of Nanotechnology, Washington, DC, September 10-11, 2013. |
R834693 (2014) R834693 (2015) |
not available |
| Presentation | Mainelis G, Calderón L, Subramaniam P, Lee K-B, Lioy PJ, Chung KF, Zhang J. Potential inhalation exposure to nanoparticles from the use of nanotechnology-enabled consumer products. Poster presented at the National Nanotechnology Initiative Workshop: Stakeholder Perspectives on the Perception, Assessment, and Management of the Potential Risks of Nanotechnology, Washington, DC, September 10-11, 2013. |
R834693 (2014) R834693 (2015) |
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| Presentation | Mainelis, G. Potential inhalation exposures to nanoparticles due to the use of nanotechnology-enabled consumer products. Presented at the 1st International Symposium on Nanoparticles/Nanomaterials and Applications, Lisbon, Portugal, January 20-22, 2014 (invited). |
R834693 (2014) R834693 (2015) R834693 (Final) |
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| Presentation | Mukherjee D, Royce S, Alexander J, Botelho D, Gow A, Chung F, Georgopoulos PG. Modeling toxicokinetics and pulmonary toxicodynamics of inhaled nanoparticles in mammalian systems. Presented at the Environmental Nanoscience Initiative Workshop and Grantee Meeting, London, England, United Kingdom, July 1-2, 2013. |
R834693 (2014) R834693 (2015) |
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| Presentation | Royce S, Mukherjee D, Cai T, Mi Z, Xu S, Mainelis G, Lioy PJ, Zhang J,Georgopoulos PG. Computational modeling to support characterization of human exposures and health risks associated with manufactured nanoparticles in consumer products. Presented at the 24th Annual International Society of Exposure Science (ISES) Conference, Cincinnati, OH, October 15, 2014. |
R834693 (2014) R834693 (2015) R834693 (Final) |
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| Presentation | Ryan M, Porter A, Chen, Theodorou I, Goode A, Leo BF, McGuire E. The biostability and immunogenic effects of silver nanostructures in simulated body fluids (SBFs) and human epithelial and blood cells. Presented at the Society of Environmental Toxicology and Chemistry (SETAC) North America 33rd Annual Meeting, Long Beach, CA, November 11-15, 2012. |
R834693 (2013) R834693 (2015) R834693 (Final) |
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| Presentation | Schwander S, Sarkar S, Zhang J, Zhang L, Baker W, Seiffert J, Tetley TD, Thorley AJ, Chung KF, Ryan M, Porter A, Lee K. Diesel exhaust particle (DEP) and DEPenvirox effects on protein and mRNA expression in stimulated THP-1 and primary human peripheral blood mononuclear cells and bioreactivity with human alveolar lung cells. Presented at the Society of Environmental Toxicology and Chemistry (SETAC) North America 33rd Annual Meeting, Long Beach, CA, November 11-15, 2012. |
R834693 (2013) R834693 (2015) R834693 (Final) |
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| Presentation | Seiffert J, Weigman C, Feng L, Baker W, Hussain F, Zhao J, Tetley T, Chung F. Determinants of inflammatory and functional toxicity of silver nanospheres in rat lung. Presented at the European Respiratory Society 23rd Annual Congress, Barcelona, Spain, September 10, 2013. |
R834693 (2014) R834693 (2015) R834693 (Final) |
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| Presentation | Tetley TD, Baker W, Thorley AJ, Seiffert J, Chung KF, Porter A, Ryan M, Schwander S, Sarkar S, Zhang J. Bioreactivity of zinc oxide and silver nanoparticles with the human lung respiratory unit and human monocytic cells. Presented at the Society of Environmental Toxicology and Chemistry (SETAC) North America 33rd Annual Meeting, Long Beach, CA, November 11-15, 2012. |
R834693 (2013) R834693 (2015) R834693 (Final) |
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| Presentation | Zhang J. RAMNUC Consortium presentation. Presented at the Environmental Nanoscience Initiative (ENI) Grantees Meeting, London, England, United Kingdom, September 18, 2011. |
R834693 (2011) R834693 (2012) R834693 (2013) R834693 (2015) R834693 (Final) |
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| Presentation | Zhang J, Solomon H, Mainelis G, Nazarenko Y, Calderon L, Subramaniam P, Lee K, Garfunkel E, Zhang L, Lioy PJ, Sarkar S, Schwander S, Baker W, Seiffert J, Thorley AJ, Tetley TD, Chung KF, Kipen H, Chen S, Ryan M, Porter A. Impact of nano-ceria fuel additive on physicochemical and toxicological properties of diesel exhaust particles. Presented at the Society of Environmental Toxicology and Chemistry (SETAC) North America 33rd Annual Meeting, Long Beach, CA, November 11-15, 2012. |
R834693 (2013) R834693 (2015) R834693 (Final) |
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| Presentation | Zhang J, Mainelis G, Tetley T, Schwander S, Lioy PJ, Georgopoulos P, Lee K-B, Garfunkel E, Di Giulio R, Ryan MP, PorterA, Sankar S, Seiffert J, Chung KF. A nano-ceria fuel additive: impact on emissions and toxicity of diesel exhaust particles. Presented at Nano2014: 9th International Conference on the Environmental Effects of Nanoparticles and Nanomaterials, Columbia, SC, September 11, 2014. |
R834693 (2014) R834693 (2015) R834693 (Final) |
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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.