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Grantee Research Project Results

2010 Progress Report: Air Pollution Mixtures: Health Effects Across Life Stages

EPA Grant Number: R834798
Center: Center for Integrative Research on Childhood Leukemia and the Environment - 2015
Center Director: Metayer, Catherine
Title: Air Pollution Mixtures: Health Effects Across Life Stages
Investigators: Koutrakis, Petros , Godleski, John J.
Current Investigators: Koutrakis, Petros , Godleski, John J. , Gold, Diane R. , Coull, Brent , Dominici, Francesca , Schwartz, Joel , Mittleman, Murray
Institution: Harvard University
EPA Project Officer: Chung, Serena
Project Period: January 1, 2011 through December 31, 2015 (Extended to December 31, 2016)
Project Period Covered by this Report: January 1, 2010 through December 31,2010
Project Amount: $7,997,561
RFA: Clean Air Research Centers (2009) RFA Text |  Recipients Lists
Research Category: Human Health , Air

Objective:

This report presents an overview and summary of the progress and achievements of the first year of funding for the Harvard University Clean Air Research Center (CLARC).  The primary objective of the Center is to estimate health effects of air pollution mixtures, sources, and individual pollutants across life stages (prenatal to senescence).  The Harvard CLARC addresses four of the six research priorities of the EPA solicitation to establish Clean Air Centers. The Center: 1) investigates the effects of pollutants and mixtures through animal and human studies; 2) identifies sub-populations that are at increased risk through the investigation of the modifying effects of gender, diabetes, obesity, socioeconomic disparities, stress, depression, violence, smoking, and omega-3 fatty acid intake in children, adults, and elderly; 3) explains regional and temporal differences in air pollution risks; and 4) examines the shapes of exposure-response relationships for associations resulting from the use of multiple exposure metrics, outcomes and populations. 
 
The Harvard CLARC has assembled a multidisciplinary team with expertise in a wide range of fields, including epidemiology, biostatistics, air pollution, exposure assessment, cell biology, pathology, and toxicology.  To meet our main objective, we have developed five research projects that will be supported by three technical Cores. We have developed a common set of hypotheses that will be tested in the different projects using a synergistic and integrative approach. Importantly, as part of the proposed Center, we will examine the consistency of findings across different health outcomes and across populations at different stages of life by: 1) relying on a common set of exposure metrics; 2) exploring the same set of susceptibility and vulnerability factors; and 3) integrating results from laboratory animal experiments with cohort and population-based studies. Specifically, we plan to: 1) investigate the acute and chronic effects of short- and long-term exposures to individual pollutants, pollution sources and multi-pollutant mixtures on: cognitive/neuropsychological function, cardiovascular/endothelial function, inflammation, birth weight/growth, and CVD-related hospitalization/mortality across life stages; and 2) identify susceptibility and vulnerability factors that modify these effects.
 
In the sections that follow, each project is discussed separately.  For each project, we summarize the objectives, progress and achievements, publications and presentations, and future activities. 
 
1.      Project 1:  Relative Toxicity of Air Pollution Mixtures.  PI: John J. Godleski, HSPH.
 
1.1 Objective of Research:  Project 1, an inhalation toxicological animal exposure study, investigates the relative toxicity of different component concentration combinations of air pollution mixtures.  These components include both particles and gases that are emitted directly from sources (primary species) or are formed in the atmosphere through a series of reactions that are predominantly photochemical (secondary species).  The project uses source specific emissions as well as ambient air or concentrated ambient particulate and our photochemical chamber technologies to generate realistic mixtures.  We are testing these specific hypotheses: (i) secondary gaseous pollutants formed from the photochemical oxidation of traffic emissions or Boston ambient gases can induce biological responses; (ii) aging Boston concentrated ambient particles (CAPs)  or source specific primary particles in the photochemical chamber enhances their toxicity; (iii) toxicological effects of photochemically aged source emissions, ambient air, or CAPs are exacerbated by co-exposure to ozone and other secondary gases; and (iv) mixture composition and toxicity exhibit inter- and intra-seasonal variability due to changes in source emissions and weather conditions.  Toxicity will be assessed in Sprague-Dawley rats by changes in 1) in vivo oxidant response, 2) blood pressure, 3) measures of inflammation, and 4) vascular blood flow/resistance. Three concurrent exposures groups (Sham, Control Exposure and Exposure) will allow us to control for the variability in CAPs composition. With this design, there can always be a direct comparison between two exposure mixtures on every exposure day, making it possible to determine which mixture is more toxic.
 
2.      Project 2:  Cognitive Decline, Cardiovascular Changes, and Biological Aging in Response to Air Pollution.  PI: Joel Schwartz, HSPH.
 
2.1 Objective of Research:  In this Project we investigate the acute and chronic effects of air pollution on cognitive and neurological impairments, systemic inflammation, and vascular dysfunction. We will determine how these effects differ depending on the composition of multi-pollutant mixtures and the source contributions to PM composition.  We then will ascertain the level of increased effects in susceptible and vulnerable subpopulations by examining modifying factors of obesity, diabetes, diet, socioeconomic position, and psychosocial stress. 
 
3.      Project 3:  Identifying the cognitive and vascular effects of air pollution sources and mixtures in the Framingham Offspring and Third Generation Cohorts.  PI: Murray Mittleman, HSPH.
 
3.1 Objective of Research:    Long- and short-term exposures to ambient air pollution are associated with adverse acute and chronic cardiovascular and perhaps cognitive function, but these effects are poorly understood.  Using data from the Framingham Offspring and Third Generation Cohorts, well-characterized populations that have not been previously investigated in association with ambient environmental exposures, we will: (1) determine whether long-term exposures to ambient pollutants and mixtures are associated with cognitive impairment and cognitive interference; (2) test whether short-term and long-term exposures to pollutants, mixtures and sources are associated with acute and chronic vascular and endothelial function; and (3) consider whether markers of biological susceptibility and vulnerability differentially influence these associations, allowing us to identify subpopulations at increased risk for harmful effects of air pollution.
 
4.      Project 4:  Longitudinal Effects of Multiple Pollutants on Child Growth, Blood Pressure and Cognition.  PI:  Diane Gold, HSPH
 
4.1 Objective of Research:  The main aim of this project is to determine, in a pre-birth cohort originating in the Greater Boston area, the health effects of prenatal and postnatal exposures to individual pollutants, sources, and pollutant mixtures on somatic growth, cardiovascular risk (blood pressure, exercise tolerance) and cognition.  Elevated blood pressure, reduced cognition, behavioral problems, and abnormal somatic growth are significant burdens on individuals, their families and society. We hypothesize that prenatal and postnatal pollution exposures (individual pollutants, sources, or mixtures) will lead to adverse changes in somatic growth, increased blood pressure, reduced cardiovascular fitness, and reduced cognition in children. The strength of the chronic and acute effects of individual pollutants on our outcomes will vary by source and mixture, as well as the timing of prenatal and postnatal exposures. Increased vulnerability or susceptibility to pollution effects on these adverse health outcomes also will result from socioeconomic disparities, stress and violence, environmental tobacco smoke, and reduced maternal and child omega-3 fatty acid intake measured in the prenatal as well as postnatal periods.
 
5.      Project 5:  A National Study to Assess Susceptibility, Vulnerability, and Effect Modification of Air Pollution Health Risks.  PI: Francesca Dominici, HSPH.
 
5.1 Objective of Research:  This national study is aimed at identifying factors that explain the heterogeneity of health risks associated with air pollution exposure. We hypothesize that such factors include medical and social conditions, conditions that modify exposure, and differences in pollution composition that modify exposure toxicity. Moreover, we hypothesize that the relevant factors vary among different health outcomes.  Our research will be fully interactive with the other Center projects. Our previous results (e.g., diabetic susceptibility) have guided their analyses, and their results have generated specific hypotheses that we will test.  We have 3 objectives. In Aims 1 and 2, we will conduct national studies of short- and long-term exposures to individual pollutants, sources, and mixtures. A main focus of our Center is to study established cohorts (NAS, Framingham, and Viva) in Massachusetts and surrounding states using novel, validated approaches to assess exposure. In Aim 3, we will complement those cohort studies, by establishing a cohort of 2.3 million Medicare enrollees residing in the same region and following its members prospectively for cause-specific hospital admissions and mortality for the period 2000-2014, and also by studying all live births in Eastern Massachusetts, geo-coded to exact address and followed for adverse birth outcomes.   

Progress Summary:

1.      Project 1:  Relative Toxicity of Air Pollution Mixtures.  PI: John J. Godleski, HSPH.
 
During the reporting period, we have completed a group of eight papers all dealing with primary and secondary emissions from power plant studies that were funded by the previous Harvard EPA PM Center and the Electric Power Research Institute. These papers have all been accepted for publication and will be published in a special issue of the journal Inhalation Toxicology.  We also have completed similar studies on emissions derived from traffic using a northeastern traffic tunnel as the source of mixed vehicular emissions, and compared the effects of the emissions with or without simulation of atmospheric aging by photochemistry and formation of secondary particles.
 
Both primary (P) and secondary particles derived from the tunnel resulted in adverse respiratory, inflammatory and cardiovascular responses. A pattern of adaptation to the exposure was found with sub-chronic exposures. Irradiation of the primary particles and gases enhanced the toxicity of the traffic emissions producing inflammatory changes in BAL, decreasing flows and volumes in breathing pattern and increasing diastolic blood pressure.  Respiratory changes were augmented with repeated exposure to the SOA (secondary particles only) and P+SOA (aged primary plus secondary particles) scenarios, suggesting a cumulative effect and a central response to the pollutants manifested by a decrease in tidal volume. P+SOA had a greater overall response than SOA only; suggesting that the particles and the more complex agglomerates formed in this multipollutant scenario greatly enhanced the toxicity of primary traffic derived particles. 
 
Blood pressure data showed an increase in systolic, diastolic and mean pressure for P, increased diastolic and decreased pulse pressure for P+SOA and increases in systolic, diastolic and pulse pressure for SOA. These changes decreased with repeated exposures overtime. Sham exposures after the last test exposure showed a sharp decrease in systolic and diastolic blood pressure in those animals previously exposed to SOA.  This pattern of decreasing changes in blood pressure during repeated exposures indicates development of a compensatory response.  We also examined how exposure to primary and secondary traffic-related particles affect DNA methylation of the promoter of endothelial nitric oxide synthase (eNOS), a gene implicated in vasoconstriction. Overall trends indicate a decrease in DNA methylation with exposure; though the data are a cross-sectional sample, the decrease in DNA methylation in the eNOS promoter suggests activation of the gene, which may result in a more rapid vasodilatory effect supports the development of a compensatory response.  Several manuscripts from this study currently are in preparation.
 
These investigations are continuing in the new CLARC, as we examine the relative toxicity of different components of air pollution mixtures, focusing on source-specific emissions and ambient particles and gases.  In the new CLARC, we are adding a rat model of vascular flow and resistance to our exposures, with excellent progress to report in techniques to prepare rats with implanted hardware for these microsphere studies.  Specifically, this includes catheterizing the left ventricle for perfusion and the thoracic aorta for sampling, and connecting these catheters to access ports implanted subcutaneously in the posterior intrascapular area.
Exposures conducted at our tunnel site in support of the new CLARC to date have included primary emissions, with some preliminary secondary exposures scheduled for August 2011.
 
2.      Project 2:  Cognitive Decline, Cardiovascular Changes, and Biological Aging in Response to Air Pollution.  PI: Joel Schwartz, HSPH.

Although the project has begun only recently, we have the following accomplishments to report:

  • A key part of this project and of all the cohort studies is development of a spatio-temporal model predicting daily PM2.5 concentrations in New England using land use regression terms and satellite remote sensing. We have developed that model, and have a paper in review describing it. We have papers in progress using it to examine the association of PM2.5 with birthweight and mortality. A poster on this work will be presented at the International Society for Environmental Epidemiology meeting in Barcelona in September.
  • We have published a paper examining the association of long-term exposure to black carbon particles at residence and cognitive function in the Normative Aging Study. This paper shows that traffic particles are associated with lower cognitive function, similar to a few years of aging, in an elderly cohort. (Power, et al., 2011 see publications).
  • We have a paper in press (Peters, et al., 2011) reporting an association between long-term lead exposure and psychosocial stress. This will serve as a template for further examination of other air pollutants.
  • We have a paper in press using our novel approach to within city survival analysis to examine the association of ozone in survival in four cohorts of potentially susceptible individuals. We find significant associations with long-term survival, only the second paper to report such results (Zanobetti and Schwartz, 2011).
  • We will present preliminary results of an analysis of long-term exposure to black carbon and Intima-media thickness of the carotid artery at the ISEE meeting in September.
  • We also will present results of a genome wide DNA methylation analysis to identify genes whose methylation is significantly perturbed by air pollution at the ISEE meeting in September.
  • We will present results of a further follow-up of the Harvard Six Cities Study at the ISEE meeting in September that examines more years of follow-up, and addresses the linearity of the dose-response curve and sensitivity to modeling assumptions.
3.      Project 3:  Identifying the Cognitive and Vascular Effects of Air Pollution Sources and Mixtures in the Framingham Offspring and Third Generation Cohorts.  PI: Murray Mittleman, HSPH.
 
Since funding began, we have worked closely with the Framingham data coordinators to complete the geocoding of all participants from the Framingham Offspring Cohort Cycles 6-8 and Third Generation Cycles 1-2.  Geocoding of the Offspring Cohort is complete and we anticipate completing geocoding of the Third Generation Cohort by the end of July 2011.
 
Preliminary analyses have evaluated the impact of short-term exposure to air pollution on vascular function as assessed by flow mediated dilation (FMD) of the brachial artery and baseline brachial artery diameter in the Framingham Offspring Cohort (Cycle 7).  We also have examined the association between short-term exposures to air pollution and repeated measures of blood pressure in this population (Cycles 6-8). We observed inverse associations between pollutant exposures (PM2.5, BC, and NO2) and flow mediated dilation (%) which achieved statistical significance for PM2.5  5 and 7 day moving averages, and 1 day averages of NO2.  Models restricted to individuals with diabetes suggested a larger magnitude of association, but wider confidence intervals. No statistically significant associations were observed for baseline diameter. These initial results were presented at the Annual Meeting of the American Heart Association Council on Cardiovascular Disease Epidemiology and Prevention in March 2011 in Atlanta, GA.  In our recent blood pressure analyses, no significant associations were observed between ambient pollution levels and systolic, diastolic, or mean arterial pressure.  These results will be presented at the International Society for Environmental Epidemiology meeting in Barcelona, Spain in September 2011.  Further analyses of both blood pressure and FMD will incorporate data from the Third Generation when they become available.
 
As an extension of the aims of this project, we evaluated the impact of long-term near-roadway exposure on renal dysfunction in a susceptible population.  In this study we evaluated the impact of living near a major roadway (A1/A2) on estimated glomerular filtration rate (eGFR) in 1120 subjects hospitalized with acute ischemic stroke.  After adjusting for potential confounders, including clinical and socioeconomic indicators, we found that living closer to a major roadway was associated with a statistically significantly lower eGFR compared with living farther away (p-trend=0.03). When considering distance to roadway as a continuous variable, we found that living <=100 m versus >500 m from a major roadway was significantly (p=0.007) associated with a 2.08 mL/min/1.73 m2 (95CI: 0.56- 3.60) lower eGFR.
 
4.      Project 4:  Longitudinal Effects of Multiple Pollutants on Child Growth, Blood Pressure and Cognition.  PI:  Diane Gold, HSPH
 
The Viva cohort consists of mothers and their offspring: 2128 live births, 1701 at 6 months, 1401 at 3 years, 1276 at 7 years.   With the goal of estimating trimester-specific, post-natal and childhood pollutant exposures, we have abstracted all pre-birth, post-natal and childhood addresses for all children. Growth, cardiovascular and cognitive outcomes have been measured and are available for analytic purposes. We have geocoded all addresses;  have estimated cumulative traffic and other GIS-based exposures;  and have created a data set with all GIS land use and weather variables needed to estimate black carbon and PM2.5 for the prenatal period and lifetime of each of the children.  Pending pollution estimates, we have evaluated the associations of residence location during pregnancy with a series of health outcomes. Fetal growth is reduced with increased cumulative traffic, urban-ness and population density.  Overweight at 6 months is increased with increased cumulative traffic density. Children in more urban areas are more obese. On-verbal and verbal cognition appeared to be reduced, and behavior difficulties appeared to be greater in children whose mothers lived in more urban areas with more traffic during their pregnancy. However, all associations were attenuated after adjusting for maternal r/e, age, maternal and paternal education, marriage status, household income, parity, smoking during pregnancy, fetal growth, gestational age at birth, bf duration, maternal Peabody Picture Vocabulary Test (3 y), HOME (Home Observation for Measurement of the Environment) score and Maternal Kaufman Brief Intelligence Test (7 y).  Other health outcomes were explored in preliminary analyses. Sleep-disordered breathing was more prevalent in urban, disadvantaged populations. Adjusting for potential confounders, increased traffic was a risk factor for bronchitis or croup at age 3 (OR=1.19; 95% CI 1.04, 1.35). Living further from major roadways at birth was protective against active asthma at ages 3 and 7 (OR=0.89 for increased distance [95% CI: 0.80, 0.99]). Living in a more densely populated, urban area of Boston was a risk factor for asthma incidence.
 
5.      Project 5:  A National Study to Assess Susceptibility, Vulnerability, and Effect Modification of Air Pollution Health Risks.  PI: Francesca Dominici, HSPH.
 
Project 5 has three aims; progress is reported for each aim.
 
Aim 1. Develop statistical methods and conduct national studies to estimate mortality and hospitalization risks associated with short-term exposures to individual pollutants, source types and air pollution mixtures.
  • We have almost completed a manuscript entitled “Effect modifiers of health effect estimates for short-term exposure to ozone and particulate matter: a review” by Antonella Zanobetti, Michelle L. Bell, and Francesca Dominici. In this manuscript, we review recent literature to summarize the state of scientific evidence on effect modification and identify consistencies across studies. We focus on time series and case-crossover studies of the effects of short-term exposure to PM or ozone on mortality and morbidity.
  • We have almost completed a manuscript entitled “Identifying the most harmful chemical components of fine particulate air pollution in 118 U.S. counties: 2000 to 2008” by Christopher Barr, David Diez, Yun Wang and Francesca Dominici. In this manuscript, we extend state-of-the-art Bayesian statistical models to identify specific combinations of constituent pollutants most harmful to a Medicare population aged 65 and older in each of 118 individual U.S. counties. Our stochastic search variable selection (SSVS) method allows us to accurately and flexibly evaluate many possible regression models in each county. We consider for inclusion the 6 most common pollution components (sulfate, nitrate, silicon, elemental carbon, organic carbon, and sodium ion), to identify the combination of pollutants most supported by the data. We interpret the full results within the emerging context of multi-pollutant regulation, and highlight the potential for these findings to power regulatory efforts that focus on specific sources within individual counties. Complete results and extensive tools for evaluation of reproducibility are made freely available online.
Aim 2. Develop statistical methods and conduct national studies to estimate mortality and hospitalization risks associated with long-term exposures to individual pollutants, source types and air pollution mixtures.
 
We have submitted a manuscript titled “An approach to multipollutant accountability research using principal stratification.” We will present this work at the September 2011 ISEE conference in Barcelona.  In this manuscript, we introduce a potential-outcomes framework for accountability research that uses a Bayesian MCMC computational strategy. The approach stratifies areas based upon the estimated causal effect of an air quality regulation on ambient air pollution and assesses the causal effect of the regulation on health outcomes within these strata. As regulations may affect concentrations of many interrelated pollutants, we extend the use of principal stratification to a multi-pollutant approach that accommodates a multivariate intermediate response vector. Furthermore, we make use of recent advancements in hierarchical modeling for point-referenced spatial data to capitalize on information contained in the geographic locations of the pollution measurement sites. Insofar as these methods rely on unobserved potential outcomes, they rely on assumptions regarding associations not identified based on observed data, indicating the importance of sensitivity analyses. We apply our method to examine whether the 1990 Clean Air Act Amendments causally affected Medicare mortality through affecting ambient concentrations of particulate matter and ozone.
 
Aim 3. Conduct two cohort studies in Massachusetts and surrounding states to estimate health risks associated with long-term exposures to individual pollutants, sources, and air pollution mixtures.
 
We currently are developing the data set and conducting exploratory analyses to estimate the long-term effects of PM2.5 on lung cancer hospital admissions.

 

Future Activities:

1.      Project 1:  Relative Toxicity of Air Pollution Mixtures.  PI: John J. Godleski, HSPH.

We will continue with our investigations as described above.  Exposures to fresh and photochemically aged source emissions/CAPs, with and without ozone and other secondary gases, will be conducted.  Toxicity of exposures will be assessed in rats using a variety of outcomes, as described above (including changes in vivo chemiluminescence, blood pressure, inflammation, and vascular flow/resistance), to determine the contribution of different components of the exposure mixture to observed biological effects.

2.      Project 2:  Cognitive Decline, Cardiovascular Changes, and Biological Aging in Response to Air Pollution.  PI: Joel Schwartz, HSPH.
 
We will continue to work on the activities proposed in our grant application. In addition, we expect to receive a grant from NIEHS to look at epigenomic effects of environmental exposures that will allow us to continue to examine exposure and epigenetic effects in the Normative Aging Study. We expect the ISEE presentations to become published papers in the next year. 
 
3.      Project 3:  Identifying the Cognitive and Vascular Effects of Air Pollution Sources and Mixtures in the Framingham Offspring and Third Generation Cohorts.  PI: Murray Mittleman, HSPH.

Future work will include integrating novel exposure assessment approaches and additional geocoding of Framingham participants into our modeling. We will complete the work we have begun on the vascular component of our project aims, and plan to begin work on examining associations between air pollution and cognitive function in the coming year. In addition, we have begun preliminary work extending the aims of our project to evaluate chronic effects of long-term exposure on atherosclerosis in the aorta based on MRI data collected on the Framingham Offspring Cohort from 2002 – 2006.

4.      Project 4:  Longitudinal Effects of Multiple Pollutants on Child Growth, Blood Pressure and Cognition.  PI:  Diane Gold, HSPH
 
We will continue analysis of exposure and outcome data.  Within the next 2 months our goals are (1) to complete BC and PM2.5 estimates that will be used for estimation of spatiotemporal variability of exposures, and (2) to link health outcome data to central site measures of pollution, for analyses dependent on temporal variability of pollution.   For future analyses, we await spatially and temporally resolved estimates of pollution exposures during fetal life and during childhood.
 
5.      Project 5:  A National Study to Assess Susceptibility, Vulnerability, and Effect Modification of Air Pollution Health Risks.  PI: Francesca Dominici, HSPH.

Aims 1 and 2: continue analysis of national short- and long-term exposures to individual pollutants, sources, and mixtures. 

Aim 3: continue development and analysis of a cohort of Medicare enrollees in Massachusetts and surrounding states for cause-specific hospital admissions and mortality; studying all live births in Eastern MA, geo-coded to exact address and followed for adverse birth outcomes. 

 


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Other center views: All 476 publications 411 publications in selected types All 411 journal articles
Publications
Type Citation Sub Project Document Sources
Journal Article Achilleos S, Kioumourtzoglou M-A, Wu C-D, Schwartz JD, Koutrakis P, Papatheodorou SI. Acute effects of fine particulate matter constituents on mortality: a systematic review and meta-regression analysis. Environment International 2017;109:89-100. R834798 (Final)
R835872 (2016)
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  • Journal Article Alexeeff SE, Schwartz J, Kloog I, Chudnovsky A, Koutrakis P, Coull BA. Consequences of kriging and land use regression for PM2.5 predictions in epidemiologic analyses: insights into spatial variability using high-resolution satellite data. Journal of Exposure Science and Environmental Epidemiology 2015;25(2):138-144. R834798 (2014)
    R834798 (Final)
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  • Journal Article Alexeeff SE, Carroll RJ, Coull B. Spatial measurement error and correction by spatial SIMEX in linear regression models when using predicted air pollution exposures. Biostatistics 2016;17(2):377-389. R834798 (Final)
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  • Journal Article Anderson GB, Bell ML. Lights out: impact of the August 2003 power outage on mortality in New York, NY. Epidemiology 2012;23(2):189-193. R834798 (2013)
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  • Journal Article Anderson GB, Krall JR, Peng RD, Bell ML. Is the relationship between ozone and mortality confounded by chemical components of particulate matter? Analysis of 7 components in 57 US communities. American Journal of Epidemiology 2012;176(8):726-732. R834798 (2013)
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  • Journal Article Anderson GB, Dominici F, Wang Y, McCormack MC, Bell ML, Peng RD. Heat-related emergency hospitalizations for respiratory diseases in the Medicare population. American Journal of Respiratory & Critical Care Medicine 2013;187(10):1098-1103. R834798 (2013)
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  • Journal Article Anderson GB, Bell ML, Peng RD. Methods to calculate the heat index as an exposure metric in environmental health research. Environmental Health Perspectives 2013;121(10):1111-1119. R834798 (2013)
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  • Journal Article Antonelli J, Cefalu M, Bornn L. The positive effects of population-based preferential sampling in environmental epidemiology. Biostatistics 2016;17(4):764-778. R834798 (Final)
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  • Journal Article Antonelli J, Schwartz J, Kloog I, Coull BA. Spatial multiresolution analysis of the effect of PM2.5 on birth weights. The Annals of Applied Statistics 2017:11(2);792-807. R834798 (Final)
    R835872 (2017)
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  • Journal Article Asselbergs, F.W., Y. Guo, E.P. van Iperen, S. Sivapalaratnam, V. et al. Large-Scale Gene-Centric Meta-analysis across 32 Studies Identifies Multiple Lipid Loci. Am J Hum Genet, 2012. 91(5):p. 823-38. R834798C005 (Final)
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    Journal Article Austin E, Coull B, Thomas D, Koutrakis P. A framework for identifying distinct multipollutant profiles in air pollution data. Environment International 2012;45:112-121. R834798 (2013)
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  • Journal Article Austin E, Coull BA, Zanobetti A, Koutrakis P. A framework to spatially cluster air pollution monitoring sites in US based on the PM2.5 composition. Environment International 2013;59:244-254. R834798 (2013)
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  • Journal Article Austin E, Zanobetti A, Coull B, Schwartz J, Gold D, Koutrakis P. Ozone trends and their relationship to characteristic weather patterns. Journal of Exposure Science and Environmental Epidemiology 2015;25(5):532-542. R834798 (Final)
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  • Journal Article Baccarelli AA, Zheng YN, Zhang X, Chang D, Liu L, Wolf KR, Zhang Z, McCracken JP, Diaz A, Bertazzi PA, Schwartz J, Wang S, Kang CM, Koutrakis P, Hou L. Air pollution exposure and lung function in highly exposed subjects in Beijing, China: a repeated-measure study. Particle and Fibre Toxicology 2014;11:51 (10 pp.). R834798 (Final)
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  • Journal Article Baccarelli A, Barretta F, Dou C, Zhang X, McCracken JP, Diaz A, Bertazzi PA, Schwartz J, Wang S, Hou L. Effects of particulate air pollution on blood pressure in a highly exposed population in Beijing, China: a repeated-measure study. Environmental Health 2011;10:108 (10 pp.). R834798 (2013)
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  • Journal Article Baccarelli, A.A. (2015). Traffic Related Air Pollution, Blood Pressure, and Adaptive Response of Mitochondrial Abundance. Circulation CIRCULATIONAHA.115.018802. R834798C002 (Final)
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    Journal Article Baja ES, Schwartz JD, Coull BA, Wellenius GA, Vokonas PS, Suh HH. Structural equation modeling of the inflammatory response to traffic air pollution. Journal of Exposure Science and Environmental Epidemiology 2013;23(3):268-274. R834798 (2013)
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  • Journal Article Baja ES, Schwartz JD, Coull BA, Wellenius GA, Vokonas PS, Suh HH. Structural equation modeling of parasympathetic and sympathetic response to traffic air pollution in a repeated measures study. Environmental Health 2013;12(1):81 (13 pp.). R834798 (Final)
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  • Journal Article Barr CD, Diez DM, Wang Y, Dominici F, Samet JM. Comprehensive smoking bans and acute myocardial infarction among Medicare enrollees in 387 US counties:1999–2008. American Journal of Epidemiology 2012;176(7):642-648. R834798 (2013)
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  • Journal Article Behbod B, Urch B, Speck M, Scott JA, Liu L, Poon R, Coull B, Schwartz J, Koutrakis P, Silverman F, Gold DR. Endotoxin in concentrated coarse and fine ambient particles induces acute systemic inflammation in controlled human exposures. Occupational and Environmental Medicine 2013;70(11):761-767. R834798 (2013)
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  • Journal Article Bell ML, Belanger K, Ebisu K, Gent JF, Leaderer BP. Relationship between birth weight and exposure to airborne fine particulate potassium and titanium during gestation. Environmental Research 2012;117:83-89. R834798 (2013)
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  • Journal Article Bell ML, Ebisu K. Environmental inequality in exposures to airborne particulate matter components in the United States. Environmental Health Perspectives 2012;120(12):1699-1704. R834798 (2013)
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  • Journal Article Bell ML, Zanobetti A, Dominici F. Evidence on vulnerability and susceptibility to health risks associated with short-term exposure to particulate matter: a systematic review and meta-analysis. American Journal of Epidemiology 2013;178(6):865-876. R834798 (2013)
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  • Journal Article Bell ML, Ebisu K, Leaderer BP, Gent JF, Lee HJ, Koutrakis P, Wang Y, Dominici F, Peng RD. Associations of PM2.5 constituents and sources with hospital admissions: analysis of four counties in Connecticut and Massachusetts (USA) for persons ≥ 65 years of age. Environmental Health Perspectives 2014;122(2):138-144. R834798 (2013)
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  • Journal Article Bell ML, Zanobetti A, Dominici F. Who is more affected by ozone pollution? A systematic review and meta-analysis. American Journal of Epidemiology 2014;180(1):15-28. R834798 (Final)
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  • Journal Article Bell ML, Son JY, Peng RD, Wang Y, Dominici F. Ambient PM2.5 and risk of hospital admissions: do risks differ for men and women? Epidemiology 2015;26(4):575-579. R834798 (Final)
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  • Journal Article Bellavia A, Urch B, Speck M, Brook RD, Scott JA, Albetti B, Behbod B, North M, Valeri L, Bertazzi PA, Silverman F, Gold D, Baccarelli AA. DNA hypomethylation, ambient particulate matter, and increased blood pressure: findings from controlled human exposure experiments. Journal of the American Heart Association 2013;2(3):e000212 (11 pp.). R834798 (2013)
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  • Journal Article Bind M-A, Zanobetti A, Gasparrini A, Peters A, Coull B, Baccarelli A, Tarantini L, Koutrakis P, Vokonas P, Schwartz J. Effects of temperature and relative humidity on DNA methylation. Epidemiology 2014;25(4):561-569. R834798 (2014)
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  • Journal Article Bind M-A, Baccarelli A, Zanobetti A, Tarantini L, Suh H, Vokonas P, Schwartz J. Air pollution and markers of coagulation, inflammation, and endothelial function: associations and epigene-environment interactions in an elderly cohort. Epidemiology 2012;23(2):332-340. R834798 (2012)
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  • Journal Article Bind M-A, Coull B, Suh H, Wright R, Baccarelli A, Vokonas P, Schwartz J. A novel genetic score approach using instruments to investigate interactions between pathways and environment: application to air pollution. PLoS One 2014;9(4):e96000 (8 pp.). R834798 (2014)
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  • Journal Article Bind M-A, Lepeule J, Zanobetti A, Gasparrini A, Baccarelli A, Coull BA, Tarantini L, Vokonas PS, Koutrakis P, Schwartz J. Air pollution and gene-specific methylation in the Normative Aging Study: association, effect modification, and mediation analysis. Epigenetics 2014;9(3):448-458. R834798 (2014)
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  • Journal Article Bind M-AC, Coull BA, Peters A, Baccarelli AA, Tarantini L, Cantone L, Vokonas PS, Koutrakis P, Schwartz JD. Beyond the mean: quantile regression to explore the association of air pollution with gene-specific methylation in the Normative Aging Study. Environmental Health Perspectives 2015;123(8):759-765. R834798 (2015)
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  • Journal Article Bind M, VanderWeele T, Schwartz J, Coull B. Quantile causal mediation analysis allowing longitudinal data. STATISTICS IN MEDICINE 2017;36(26):4182-4195 R834798 (Final)
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  • Journal Article Bobb JF, Dominici F, Peng RD. Reduced hierarchical models with application to estimating health effects of simultaneous exposure to multiple pollutants. Journal of the Royal Statistical Society: Series C (Applied Statistics) 2013;62(3):451-472. R834798 (2012)
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  • Journal Article Bobb JF, Peng RD, Bell ML, Dominici F. Heat-related mortality and adaptation to heat in the United States. Environmental Health Perspectives 2014;122(8):811-816. R834798 (2014)
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  • Journal Article Bobb JF, Obermeyer Z, Wang Y, Dominici F. Cause-specific risk of hospital admission related to extreme heat in older adults. JAMA 2014;312(24):2659-2667. R834798 (Final)
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  • Journal Article Bobb JF, Valeri L, Claus Henn B, Christiani DC, Wright RO, Mazumdar M, Godleski JJ, Coull BA. Bayesian kernel machine regression for estimating the health effects of multi-pollutant mixtures. Biostatistics 2015;16(3):493-508. R834798 (Final)
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  • Journal Article Boehm Vock LF, Reich BJ, Fuentes M, Dominici F. Spatial variable selection methods for investigating acute health effects of fine particulate matter components. Biometrics 2015;71(1):167-177. R834798 (Final)
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  • Journal Article Bose S, Chiu Y-HM, Hsu H-HL, Di Q, Rosa MJ, Lee A, Kloog I, Wilson A, Schwartz J, Wright RO, Cohen S, Coull BA, Wright RJ. Prenatal nitrate exposure and childhood asthma. Influence of maternal prenatal stress and fetal sex. American Journal of Respiratory and Critical Care Medicine 2017;196(11):1396-1403. R834798 (Final)
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  • Journal Article Bottino CJ, Rifas-Shiman SL, Kleinman KP, Oken E, Redline S, Gold D, Schwartz J, Melly SJ, Koutrakis P, Gillman MW, Taveras EM. The association of urbanicity with infant sleep duration. Health & Place 2012;18(5):1000-1005. R834798 (2013)
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  • Journal Article Bravo MA, Fuentes M, Zhang Y, Burr MJ, Bell ML. Comparison of exposure estimation methods for air pollutants: ambient monitoring data and regional air quality simulation. Environmental Research 2012;116:1-10. R834798 (2013)
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  • Journal Article Bravo MA, Son J, de Freitas CU, Gouveia N, Bell ML. Air pollution and mortality in Sao Paulo, Brazil: effects of multiple pollutants and analysis of susceptible populations. Journal of Exposure Science & Environmental Epidemiology 2016;26(2):150-161. R834798 (Final)
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  • Journal Article Bravo MA, Ebisu K, Dominici F, Wang Y, Peng RD, Bell ML. Airborne fine particles and risk of hospital admissions for understudied populations: effects by urbanicity and short-term cumulative exposures in 708 U.S. counties. Environmental Health Perspectives 2017;125(4):594-601. R834798 (Final)
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  • Journal Article Breysse PN, Delfino RJ, Dominici F, Elder ACP, Frampton MW, Froines JR, Geyh AS, Godleski JJ, Gold DR, Hopke PK, Koutrakis P, Li N, Oberdorster G, Pinkerton KE, Samet JM, Utell MJ, Wexler AS. US EPA particulate matter research centers: summary of research results for 2005–2011. Air Quality, Atmosphere & Health 2013;6(2):333-355. R834798 (2013)
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  • Journal Article Busenkell E, Collins C, Moy M, Hart J, Grady S, Coull B, Schwartz J, Koutrakis P, Harshick E. Modification of associations between indoor particulate matter and systemic inflammation in individuals with COPD. ENVIRONMENT RESEARCH 2022;209(112802). R834798 (Final)
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  • Journal Article Carll AP, Crespo SM, Mauricio Filho S, Zati DH, Coull BA, Diaz EA, Raimundo RD, Jaeger TN, Ricci-Vitor AL, Papapostolou V, Lawrence JE, Garner DM, Perry BS, Harkema JR, Godleski JJ. Inhaled ambient-level traffic-derived particulates decrease cardiac vagal influence and baroreflexes and increase arrhythmia in a rat model of metabolic syndrome. Particle and Fibre Toxicology 2017;14(1):16 (15 pp.). R834798 (2016)
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  • Journal Article Carmona JJ, Sofer T, Hutchinson J, Cantone L, Coull B, Maity A, Vokonas P, Lin X, Schwartz J, Baccarelli AA. Short-term airborne particulate matter exposure alters the epigenetic landscape of human genes associated with the mitogen-activated protein kinase network: a cross-sectional study. Environmental Health 2014;13:94 (14 pp.). R834798 (Final)
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  • Journal Article Carreras H, Zanobetti A, Koutrakis P. Effect of daily temperature range on respiratory health in Argentina and its modification by impaired socio-economic conditions and PM10 exposures. Environmental Pollution 2015;206:175-182. R834798 (2015)
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  • Journal Article Castillo M, Wagner J, Casuccio G, West R, Freedman F, Eisl H, Wang Z, Yip J, Kinney P. Field testing a low-cost passive aerosol sampler for long-term measurement of ambient PM2.5 concentrations and particle composition. ATMOSPHERIC ENVIRONMENT 2019;216:116905. R834798 (Final)
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  • Journal Article Cefalu M, Dominici F. Does exposure prediction bias health-effect estimation?: The relationship between confounding adjustment and exposure prediction. Epidemiology 2014;25(4):583-590. R834798 (Final)
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  • Journal Article Cefalu M, Dominici F, Arvold N, Parmigiani G. Model averaged double robust estimation. Biometrics 2017;73(2):410-421. R834798 (Final)
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  • Journal Article Chiu Y-HM, Coull BA, Sternthal MJ, Kloog I, Schwartz J, Cohen S, Wright RJ. Effects of prenatal community violence and ambient air pollution on childhood wheeze in an urban population.Journal of Allergy and Clinical Immunology 2014;133(3):713-722.e4. R834798 (Final)
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  • Journal Article Chiu Y-HM, Hsu H-HL, Coull BA, Bellinger DC, Kloog I, Schwartz J, Wright RO, Wright RJ. Prenatal particulate air pollution and neurodevelopment in urban children:examining sensitive windows and sex-specific associations. Environment International 2016;87:56-65. R834798 (Final)
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  • Journal Article Chudnovsky AA, Lee HJ, Kostinski A, Kotlov T, Koutrakis P. Prediction of daily fine particulate matter concentrations using aerosol optical depth retrievals from the Geostationary Operational Environmental Satellite (GOES). Journal of the Air & Waste Management Association 2012;62(9):1022-1031. R834798 (2013)
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  • Journal Article Chudnovsky AA, Tang C, Lyapustin A, Wang Y, Schwartz J, Koutrakis P. A critical assessment of high-resolution aerosol optical depth retrievals for fine particulate matter predictions. Atmospheric Chemistry and Physics 2013;13(21):10907-10917. R834798 (2013)
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  • Journal Article Chudnovsky AA, Koutrakis P, Kloog I, Melly S, Nordio F, Lyapustin A, Wang Y, Schwartz J. Fine particulate matter predictions using high resolution Aerosol Optical Depth (AOD) retrievals. Atmospheric Environment 2014;89:189-198. R834798 (2014)
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  • Journal Article Chudnovsky AA, Lyapustin A, Wang Y, Tang C, Schwartz J, Koutrakis P. High resolution aerosol data from MODIS satellite for urban air quality studies. Central European Journal of Geosciences 2014:6(1):17-26. R834798 (2014)
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  • Journal Article Chudnovsky AA, Koutrakis P, Kostinski A, Proctor SP, Garshick E. Spatial and temporal variability in desert dust and anthropogenic pollution in Iraq, 1997–2010. Journal of the Air & Waste Management Association 2017;67(1):17-26. R834798 (Final)
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  • Journal Article Chudnovsky AA, Kostinski A, Lyapustin A, Koutrakis P. Spatial scales of pollution from variable resolution satellite imaging. Environmental Pollution 2013;172:131-138. R834798 (2013)
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  • Journal Article Chung M, Wang DD, Rizzo AM, Gachette D, Delnord M, Parambi R, Kang C-M, Brugge D. Association of PNC, BC, and PM2.5 measured at a central monitoring site with blood pressure in a predominantly near highway population. International Journal of Environmental Research and Public Health 2015;12(3):2765-2780. R834798 (2015)
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  • Journal Article Chung Y, Dominici F, Wang Y, Coull BA, Bell ML. Associations between long-term exposure to chemical constituents of fine particulate matter (PM2.5) and mortality in Medicare enrollees in the eastern United States. Environmental Health Perspectives 2015;123(5):467-474. R834798 (2014)
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    Journal Article Colicino E, Power MC, Cox DG, Weisskopf MG, Hou L, Alexeeff SE, Sanchez-Guerra M, Vokonas P, Spiro III A, Schwartz J, Baccarelli AA. Mitochondrial haplogroups modify the effect of black carbon on age‐related cognitive impairment. Environmental Health 2014;13(1):42. R834798 (Final)
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  • Journal Article Colicino E, Giuliano G, Power MC, Lepeule J, Wilker EH, Vokonas P, Brennan KJ, Fossati S, Hoxha M, Spiro III A, Weisskopf MG Schwartz J, Baccarelli AA. Long-term exposure to black carbon, cognition and single nucleotide polymorphisms in microRNA processing genes in older men. Environment International 2016;88:86-93. R834798 (Final)
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  • Journal Article Colicino E, Wilson A, Frisardi MC, Prada D, Power MC, Hoxha M, Dioni L, Spiro III A, Vokonas PS, Weisskopf MG, Schwartz JD, Baccarelli AA. Telomere length, long-term black carbon exposure, and cognitive function in a cohort of older men:the VA Normative Aging Study. Environmental Health Perspectives 2017;125(1):76-81. R834798 (Final)
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  • Journal Article Correia AW, Pope III CA, Dockery DW, Wang Y, Ezzati M, Dominici F. Effect of air pollution control on life expectancy in the United States: an analysis of 545 U.S. counties for the period 2000 to 2007. Epidemiology 2013;24(1):23-31. R834798 (2012)
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  • Journal Article Cowell WJ, Bellinger DC, Coull BA, Gennings C, Wright RO, Wright RJ. Associations between prenatal exposure to black carbon and memory domains in urban children: modification by sex and prenatal stress. PLoS One 2015;10(11):e0142492 (14 pp.). R834798 (Final)
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  • Journal Article Dai L, Zanobetti A, Koutrakis P, Schwartz JD. Associations of fine particulate matter species with mortality in the United States: a multicity time-series analysis. Environmental Health Perspectives 2014;122(8):837-842. R834798 (2014)
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  • Journal Article Dai L, Kloog I, Coull BA, Sparrow D, Spiro III A, Vokonas PS, Schwartz JD. Cognitive function and short-term exposure to residential air temperature: a repeated measures study based on spatiotemporal estimates of temperature. Environmental Research 2016;150:446-451. R834798 (Final)
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  • Journal Article Deslauriers J, Redlich C, Kang C, Grady S, Slade M, Koutrakis P, Garshick E. Determinants of indoor carbonaceous aerosols in homes in the Northeast United States. JOURNAL OF THE EXPOSURE SCIENCE & ENVIRONMENTAL EPIDEMIOLOGY 2022;. R834798 (Final)
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  • Journal Article Di Q, Dai L, Wang Y, Zanobetti A, Choirat C, Schwartz JD, Dominici F. Association of short-term exposure to air pollution with mortality in older adults. JAMA 2017;318(24):2446-2456. R834798 (Final)
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  • Journal Article Di Q, Wang Y, Zanobetti A, Wang Y, Koutrakis P, Choirat C, Dominici F, Schwartz JD. Air pollution and mortality in the Medicare population. New England Journal of Medicine 2017;376(26):2513-2522. R834798 (Final)
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  • Journal Article Diaz EA, Lemos M, Coull B, Long MS, Rohr AC, Ruiz P, Gupta T, Kang C-M, Godleski JJ. Toxicological Evaluation of Realistic Emission Source Aerosols (TERESA)--power plant studies: assessment of breathing pattern. Inhalation Toxicology 2011;23(Suppl 2):42-59. R834798 (2013)
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  • Journal Article Diaz EA, Chung Y, Papapostolou V, Lawrence J, Long MS, Hatakeyama V, Gomes B, Calil Y, Sato R, Koutrakis P, Godleski JJ. Effects of fresh and aged vehicular exhaust emissions on breathing pattern and cellular responses – pilot single vehicle study. Inhalation Toxicology 2012;24(5):288-295. R834798 (2012)
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  • Journal Article Diaz EA, Chung Y, Lamoureux DP, Papapostolou V, Lawrence J, Long MS, Mazzaro V, Buonfiglio H, Sato R, Koutrakis P, Godleski JJ. Effects of fresh and aged traffic-related particles on breathing pattern, cellular responses, and oxidative stress. Air Quality, Atmosphere & Health 2013;6(2):431-444. R834798 (2012)
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  • Journal Article Diez DM, Dominici F, Zarubiak D, Levi JI. Statistical approaches for identifying air pollutant mixtures associated with aircraft departures at Los Angeles International Airport. Environmental Science & Technology 2012;46(15):8229-8235. R834798 (2013)
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  • Journal Article Dominici F, Mittleman MA. China’s air quality dilemma:reconciling economic growth with environmental protection. Journal of the American Medical Association 2012;307(19):2100-2102 (editorial). R834798 (2012)
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  • Journal Article Dominici F, Greenstone M, Sunstein CR. Particulate matter matters. Science 2014;344(6181):257-259. R834798 (Final)
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  • Journal Article Dominici F, Wang Y, Correia AW, Ezzati M, Pope IIII CA, Dockery DW. Chemical composition of fine particulate matter and life expectancy: in 95 US counties between 2002 and 2007. Epidemiology 2015;26(4):556-564. R834798 (Final)
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  • Journal Article Dorans KS, Wilker EH, Li W, Rice MB, Ljungman PL, Schwartz J, Coull BA, Kloog I, Koutrakis P, D’Agostino RB, Massaro JM, Hoffmann U, O'Donnell J, Mittleman MA. Residential proximity to major roads, exposure to fine particulate matter, and coronary artery calcium: the Framingham Heart Study. Arteriosclerosis, Thrombosis, and Vascular Biology 2016;36(8):1679-1685. R834798 (Final)
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  • Journal Article Dorans KS, Wilker EH, Li W, Rice MB, Ljungman PL, Schwartz J, Coull BA, Kloog I, Koutrakis P, D’Agostino RB, Massaro JM, Hoffmann U, O'Donnell J, Mittleman MA. Residential proximity to major roads, exposure to fine particulate matter and aortic calcium:the Framingham Heart Study, a cohort study. BMJ Open . 2017;7(3):e013455. R834798 (Final)
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  • Journal Article Dorans KS, Wilker EH, Li W, et al. Residential proximity to major roads, exposure to fine particulate matter and aortic calcium:The Framingham Heart Study, a cohort study. BMJ open. 2017;7:e013455. R834798C003 (Final)
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    Journal Article dos Santos N, Zilli V, Nascimento S, Mazzilli B, Saki M, Saueia C, Saldiva De Andre C, Justo L, Tisti M, Koutrakis P. Levels of Polonium-210 in brain and pulmonary tissues:Preliminary study in autopsies conducted in the city of Sao Paulo, Brazil. SCIENTIFIC REPORTS 2020;10(1):180. R834798 (Final)
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  • Journal Article Ebisu K, Bell ML. Airborne PM2.5 chemical components and low birth weight in the northeastern and mid-Atlantic regions of the United States. Environmental Health Perspectives 2012;120(12):1746-1752. R834798 (2013)
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  • Journal Article Ebisu K, Belanger K, Bell ML. The association between airborne PM2.5 chemical constituents and birth weight--implication of buffer exposure assignment. Environmental Research Letters 2014;9(8):084007 (12 pp.). R834798 (Final)
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  • Journal Article Ebisu K, Holford TR, Bell ML. Association between greenness, urbanicity, and birth weight. Science of the Total Environment 2016;542(Pt A):750-756. R834798 (Final)
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  • Journal Article Ebisu K, Berman JD, Bell ML. Exposure to coarse particulate matter during gestation and birth weight in the U.S. Environment International 2016;94:519-524. R834798 (Final)
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  • Journal Article Fang SC, Mehta AJ, Alexeeff SE, Gryparis A, Coull B, Vokonas P, Christiani DC, Schwartz J. Residential black carbon exposure and circulating markers of systemic inflammation in elderly males: the normative aging study. Environmental Health Perspectives 2012;120(5):674-680. R834798 (2013)
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  • Journal Article Fang SC, Schwartz J, Yang M, Yaggi HK, Bliwise DL, Araujo AB. Traffic‐related air pollution and sleep in the Boston Area Community Health Survey. Journal of Exposure Science & Environmental Epidemiology 2015;25(5):451-456. R834798 (Final)
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  • Journal Article Fiffer M, Kang C, Requia W, Koutrakis P. Long-term impact of PM(2.5)mass and sulfur Reductions on ultrafine particle trends in Boston, MA from 1999 to 2018. JOURNAL OF THE AIR & WASTE MANAGEMENT ASSOCIATION 2020;70(7):700-707. R834798 (Final)
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  • Journal Article Fleisch AF, Gold DR, Rifas-Shiman SL, Koutrakis P, Schwartz JD, Kloog I, Melly S, Coull BA, Zanobetti A, Gillman MW, Oken E. Air pollution exposure and abnormal glucose tolerance during pregnancy: the Project Viva cohort. Environmental Health Perspectives 2014:122(4):378-383. R834798 (2014)
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  • Journal Article Fleisch AF, Kloog I, Luttmann-Gibson H, Gold DR, Oken E, and Schwartz JD. Air Pollution Exposure and Gestational Diabetes Mellitus Among Pregnant Women in Massachusetts:a Cohort Study. Environmental Health 2016; 15:40-48. R834798 (Final)
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  • Journal Article Fleisch AF, Kloog I, Luttmann-Gibson H, Gold DR, Oken E, Schwartz JD. Air pollution exposure and gestational diabetes mellitus among pregnant women in Massachusetts: a Cohort Study. Environmental Health 2016;15(1):40 (9 pp.). R834798 (2016)
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  • Journal Article Fleisch AF, Luttmann‐Gibson H, Perng W, Rifas‐Shiman SL, Coull BA, Kloog I, Koutrakis P, Schwartz JD, Zanobetti A, Mantzoros CS, Gillman MW, Gold DR, Oken E. Prenatal and early life exposure to traffic pollution and cardiometabolic health in childhood. Pediatric Obesity 2017;12(1):48-57. R834798 (Final)
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  • Journal Article Fossati S, Baccarelli A, Zanobetti A, Hoxha M, Vokonas PS, Wright RO, Schwartz J. Ambient particulate air pollution and MicroRNAs in elderly men. Epidemiology 2014;25(1):68-78. R834798 (2014)
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  • Journal Article Fuller CH, Brugge D, Williams PL, Mittleman MA, Durant JL, Spengler JD. Estimation of ultrafine particle concentrations at near-highway residences using data from local and central monitors. Atmospheric Environment 2012;57:257-265. R834798 (2013)
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  • Journal Article Fuller CH, Williams PL, Mittleman MA, Patton AP, Spengler JD, Brugge D. Response of biomarkers of inflammation and coagulation to short-term changes in central site, local, and predicted particle number concentrations. Annals of Epidemiology 2015;25(7):505-511. R834798 (Final)
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  • Journal Article Gaskins A, Tang Z, Hood R, Ford J, Schwartz J, Jones D, Laden F, Liang D. Periconception air pollution, metabolomic biomarkers, and fertility among women undergoing assisted reproduction. ENVIRONMENTAL INTERNATIONAL 2021;155:106666. R834798 (Final)
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  • Journal Article Godleski JJ, Diaz EA, Lemos M, Long M, Ruiz P, Gupta T, Kang C-M, Coull B. Toxicological Evaluation of Realistic Emission Source Aerosols (TERESA)-power plant studies: assessment of cellular responses. Inhalation Toxicology 2011;23(Suppl 2):60-74. R834798 (2013)
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  • Journal Article Godleski JJ, Rohr AC, Kang CM, Diaz EA, Ruiz PA, Koutrakis P. Toxicological Evaluation of Realistic Emission Source Aerosols (TERESA): introduction and overview. Inhalation Toxicology 2011;23(Suppl 2):1-10. R834798 (2013)
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  • Journal Article Godleski JJ, Rohr AC, Coull BA, Kang CM, Diaz EA, Koutrakis P. Toxicological Evaluation of Realistic Emission Source Aerosols (TERESA): summary and conclusions. Inhalation Toxicology 2011;23(Suppl 2):95-103. R834798 (2013)
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  • Journal Article Godleski J, Rohr A, Coull B, Kang C, Diaz E, Koutrakis P. Toxicological evaluation of realistic emission source aerosols TERESA:summary and conclusions. INHALATION TOXICOLOGY 2011;23:95-103. R834798 (Final)
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  • Journal Article Gold DR, Mittleman MA. New insights into pollution and the cardiovascular system: 2010 to 2012. Circulation 2013;127(18):1903-1913. R834798 (2013)
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  • Journal Article Grady ST, Koutrakis P, Hart JE, Coull BA, Schwartz J, Laden F, Zhang JJ, Gong J, Moy ML, Garshick E. Indoor black carbon of outdoor origin and oxidative stress biomarkers in patients with chronic obstructive pulmonary disease. Environment International 2018;115:188-195. R834798 (Final)
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  • Journal Article Guo L, Byun H-M, Zhong J, Motta V, Barupal J, Zheng Y, Dou C, Zhang F, McCracken JP, Diaz A, Marco SG, Colicino S, Schwartz J, Wang S, Hou L, Baccarelli AA. Effects of short-term exposure to inhalable particulate matter on DNA methylation of tandem repeats. Environmental and Molecular Mutagenesis 2014;55(4):322-335. R834798 (Final)
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  • Journal Article Habre R, Coull B, Koutrakis P. Impact of source collinearity in simulated PM2.5 data on the PMF receptor model solution. Atmospheric Environment 2011;45(38):6938-6946. R834798 (2013)
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  • Journal Article Harris MH, Gold DR, Rifas-Shiman SL, Melly SJ, Zanobetti A, Coull BA, Schwartz JD, Gryparis A, Kloog I, Koutrakis P, Bellinger DC, White RF, Sagiv SK, Oken E. Prenatal and childhood traffic-related pollution exposure and childhood cognition in the Project Viva Cohort (Massachusetts, USA). Environmental Health Perspectives 2015;123(10):1072-1078. R834798 (2015)
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  • Journal Article Harris MH, Gold DR, Rifas-Shiman SL, Melly SJ, Zanobetti A, Coull BA, Schwartz JD, Gryparis A, Kloog I, Koutrakis P, Bellinger DC, Belfort MB, Webster TF, White RF, Sagiv SK, Oken E. Prenatal and childhood traffic-related air pollution exposure and childhood executive function and behavior. Neurotoxicology and Teratology 2016;57(Sep-Oct):60-70. R834798 (Final)
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  • Journal Article Hart JE, Grady ST, Laden F, Coull BA, Koutrakis P, Schwartz JD, Moy ML, Garshick E. Effects of indoor and ambient black carbon and PM 2.5 on pulmonary function among individuals with COPD. Environmental Health Perspectives 2018;126(12):127008. R834798 (Final)
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  • Journal Article Hoffmann B, Luttmann-Gibson H, Cohen A, Zanobetti A, de Souza C, Foley C, Suh HH, Coull BA, Schwartz J, Mittleman M, Stone P, Horton E, Gold DR. Opposing effects of particle pollution, ozone, and ambient temperature on arterial blood pressure. Environmental Health Perspectives 2012;120(2):241-246. R834798 (2012)
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  • Journal Article Hood R, James P, Fong K, Minguez-Alcaron L, Coull B, Schwartz J, Kloog I, Laden F, Gasking A. The influence of fine particulate matter on the association between residential greenness and ovarian reserve. ENVIRONMENTAL RESEARCH 2021;197:111162. R834798 (Final)
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  • Journal Article Hou L, Wang S, Dou C, Zhang X, Yu Y, Zheng Y, Avula U, Hoxha M, Díaz A, McCracken J, Barretta F, Marinelli B, Bertazzi PA, Schwartz J, Baccarelli AA. Air pollution exposure and telomere length in highly exposed subjects in Beijing, China: a repeated-measure study. Environment International 2012;48:71-77. R834798 (2013)
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  • Journal Article Hou L, Zhang X, Dioni L, Barretta F, Dou C, Zheng Y, Hoxha M, Bertazzi PA, Schwartz J, Wu S, Wang S, Baccarelli AA. Inhalable particulate matter and mitochondrial DNA copy number in highly exposed individuals in Beijing, China: a repeated-measure study. Particle and Fibre Toxicology 2013;10:17. R834798 (2013)
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  • Journal Article Hou L, Zhang X, Zheng Y, Wang S, Dou C, Guo L, Byun H-M, Motta V, McCracken J, Díaz A, Kang C-M, Koutrakis P, Bertazzi PA, Li J, Schwartz J, Baccarelli AA. Altered methylation in tandem repeat element and elemental component levels in inhalable air particles. Environmental and Molecular Mutagenesis 2014;55(3):256-265. R834798 (2014)
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  • Journal Article Hou L, Barupal J, Zhang W, Zheng YA, Liu L, Zhang X, Dou C, McCracken JP, Diaz A, Motta V, Sanchez-Guerra M, Wolf KR, Bertazzi PA, Schwartz JD, Wang S, Baccarelli AA. Particulate air pollution exposure and expression of viral and human microRNAs in blood: The Beijing Truck Driver Air Pollution Study. Environmental Health Perspectives 2016;124(3):344-350. R834798 (Final)
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  • Journal Article Howe C, Coull B, Papatheodorou S, Luttmann-Gibson H, Rifas-Shiman S, Wilson A, Kloog I, Di Q, Zanobetti A, Koutrakis P, Schwartz J, Oken E, Gold D. Relative humidity, temperature, and hypertensive disorders of pregnancy: Findings from the Project Viva cohort. ENVIRONMENTAL RESEARCH 2024;257(119211) R834798 (Final)
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  • Journal Article Hsu H-HL, Chiu Y-HM, Coull BA, Kloog I, Schwartz J, Lee A, Wright RO, Wright RJ. Prenatal particulate air pollution and asthma onset in urban children. Identifying sensitive windows and sex differences. American Journal of Respiratory and Critical Care Medicine 2015;192(9):1052-1059. R834798 (2015)
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  • Journal Article Huang K, Yang X, Liang F, Liu F, Li J, Xiao Q, Chen J, Liu X, Cao J, Shen C, Yu L, Lu F, Wu X, Zhao L, Wu X, Li Y, Hu D, Huang J, Liu Y, Lu X, Gu D. Long-Term Exposure to Fine Particulate Matter and Hypertension Incidence in China:The China-PAR Cohort Study. HYPERTENSION 2019;242:675-683. R834798 (Final)
    R835869 (Final)
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  • Journal Article Hwang S, Hood R, Hauser R, Schwartz J, Laden F, Jones D, Liang D, Gaskins A. Using follicular fluid metabolomics to investigate the association between air pollution and oocyte quality. ENVIRONMENTAL INTERNATIONAL 2022;169(107522). R834798 (Final)
    R835872 (2021)
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  • Journal Article Ierodiakonou D, Zanobetti A, Coull BA, Melly S, Postma DS, Boezen HM, Vonk JM, Williams PV, Shapiro GG, McKone EF, Hallstrand TS, Koenig JQ, Schildcrout JS, Lumley T, Fuhlbrigge AN, Koutrakis P, Schwartz J, Weiss ST, Gold DR, Childhood Asthma Management Program Research Group. Ambient air pollution, lung function, and airway responsiveness in asthmatic children. Journal of Allergy and Clinical Immunology 2016;137(2):390-399. R834798 (2015)
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  • Journal Article Jhun I, Oyola P, Moreno F, Castillo MA, Koutrakis P. PM2.5 mass and species trends in Santiago, Chile, 1998 to 2010: the impact of fuel-related interventions and fuel sales. Journal of the Air & Waste Management Association 2013;63(2):161-169. R834798 (2013)
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  • Journal Article Jhun I, Coull BA, Schwartz J, Hubbell B, Koutrakis P. The impact of weather changes on air quality and health in the United States in 1994-2012. Environmental Research Letters 2015;10(8):084009 (11 pp.). R834798 (Final)
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  • Journal Article Jhun I, Coull BA, Zanobetti A, Koutrakis P. The impact of nitrogen oxides concentration decreases on ozone trends in the USA. Air Quality, Atmosphere & Health 2015;8(3):283-292. R834798 (2014)
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  • Journal Article Joyce BT, Gao T, Zheng Y, Liu L, Zhang W, Dai Q, Shrubsole MJ, Hibler EA, Cristofanilli M, Zhang H, Yang H, Vokonas P, Cantone L, Schwartz J, Baccarelli A, Hou L. Prospective changes in global DNA methylation and cancer incidence and mortality. British Journal of Cancer 2016;115(4):465-472. R834798 (Final)
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  • Journal Article Kang C-M, Gupta T, Ruiz PA, Wolfson JM, Ferguson ST, Lawrence JE, Rohr AC, Godleski J, Koutrakis P. Aged particles derived from emissions of coal-fired power plants: the TERESA field results. Inhalation Toxicology 2011;23(Suppl 2):11-30. R834798 (2013)
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  • Journal Article Kang C, Achilleos S, Lawrence J, Wolfson J, Koutrakis P. Interlab Comparison of Elemental Analysis for Low Ambient Urban PM2.5 Levels. ENVIRONMENTAL SCIENCE AND TECHNOLOGY 2014;48(20):12150-12156. R834798 (Final)
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  • Journal Article Kingsley SL, Eliot MN, Glazer K, Awad YA, Schwartz JD, Savitz DA, Kelsey KT, Marsit CJ, Wellenius GA. Maternal ambient air pollution, preterm birth and markers of fetal growth in Rhode Island:results of a hospital-based linkage study. Journal of Epidemiology and Community Health 2017;71(12):1131-1136. R834798 (Final)
    R835872 (2017)
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  • Journal Article Kioumourtzoglou MA, Coull BA, Dominici F, Koutrakis P, Schwartz J, Suh H. The impact of source contribution uncertainty on the effects of source-specific PM2.5 on hospital admissions:a case study in Boston, MA. Journal of Exposure Science and Environmental Epidemiology 2014;24(4):365-371. R834798 (2014)
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  • Journal Article Kioumourtzoglou M-A, Zanobetti A, Schwartz JD, Coull BA, Dominici F, Suh HH. The effect of primary organic particles on emergency hospital admissions among the elderly in 3 US cities. Environmental Health 2013;12(1):68 (10 pp.). R834798 (2013)
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  • Journal Article Kioumourtzoglou M-A, Austin E, Koutrakis P, Dominici F, Schwartz J, Zanobetti A. PM2.5 and survival among older adults: effect modification by particulate composition. Epidemiology 2015;26(3):321-327. R834798 (2015)
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  • Journal Article Kioumourtzoglou M-A, Schwartz JD, Weisskopf MG, Melly SJ, Wang Y, Dominici F, Zanobetti A. Long-term PM2.5 exposure and neurological hospital admissions in the Northeastern United States. Environmental Health Perspectives 2016;124(1):23-29. R834798 (Final)
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  • Journal Article Kioumourtzoglou, M.-A., Austin, E., Koutrakis, P., Dominici, F.S., J. D., and Zanobetti, A. (2015). PM2.5 and Survival Among Older Adults Effect Modification by Particulate Composition. Epidemiology 26, 321-327. R834798C005 (Final)
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  • Journal Article Kioumourtzoglou, M.-A., Schwartz, J., Weisskopf, M.G., Melly, S., Wang, Y., Dominici, F., and Zanobetti, A. (2015). Long-term PM2.5 Exposure and Neurological Hospital Admissions in the Northeastern United States. Environmental Health Perspectives 124, 23-29. R834798C005 (Final)
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  • Journal Article Kloog I, Koutrakis P, Coull BA, Lee HJ, Schwartz J. Assessing temporally and spatially resolved PM2.5 exposures for epidemiological studies using satellite aerosol optical depth measurements. Atmospheric Environment 2011;45(35):6267-6275. R834798 (2012)
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  • Journal Article Kloog I, Coull BA, Zanobetti A, Koutrakis P, Schwartz JD. Acute and chronic effects of particles on hospital admissions in New-England. PLoS ONE 2012;7(4):e34664 (8 pp.). R834798 (2012)
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  • Journal Article Kloog I, Chudnovsky A, Koutrakis P, Schwartz J. Temporal and spatial assessments of minimum air temperature using satellite surface temperature measurements in Massachusetts, USA. Science of The Total Environment 2012;432:85-92. R834798 (2013)
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  • Journal Article Kloog I, Melly SJ, Ridgway WL, Coull BA, Schwartz J. Using new satellite based exposure methods to study the association between pregnancy PM2.5 exposure, premature birth and birth weight in Massachusetts. Environmental Health 2012;11:40 (8 pp.). R834798 (2012)
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  • Journal Article Kloog I, Nordio F, Coull BA, Schwartz J. Incorporating local land use regression and satellite aerosol optical depth in a hybrid model of spatiotemporal PM2.5 exposures in the Mid-Atlantic states. Environmental Science & Technology 2012;46(21):11913-11921. R834798 (2013)
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  • Journal Article Kloog I, Ridgway B, Koutrakis P, Coull BA, Schwartz JD. Long-and short-term exposure to PM2.5 and mortality:using novel exposure models. Epidemiology 2013;24(4):555-561. R834798 (2013)
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  • Journal Article Kloog I, Nordio F, Zanobetti A, Coull BA, Koutrakis P, Schwartz JD. Short term effects of particle exposure on hospital admissions in the Mid-Atlantic states: a population estimate. PLoS ONE 2014;9(2):e88578 (7 pp.). R834798 (2014)
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  • Journal Article Kloog I, Nordio F, Coull BA, Schwartz J. Predicting spatiotemporal mean air temperature using MODIS satellite surface temperature measurements across the Northeastern USA. Remote Sensing of Environment 2014;150:132-139. R834798 (2014)
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  • Journal Article Kloog I, Chudnovsky AA, Just AC, Nordio F, Koutrakis P, Coull BA, Lyapustin A, Wang Y, Schwartz J. A new hybrid spatio-temporal model for estimating daily multi-year PM2.5 concentrations across northeastern USA using high resolution aerosol optical depth data. Atmospheric Environment 2014;95:581-590. R834798 (Final)
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  • Journal Article Kloog I, Zanobetti A, Nordio F, Coull BA, Baccarelli AA, Schwartz J. Effects of airborne fine particles (PM2.5 ) on deep vein thrombosis admissions in the northeastern United States. Journal of Thrombosis and Haemostasis 2015;13(5):768-774. R834798 (2015)
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  • Journal Article Kloog I, Melly SJ, Coull BA, Nordio F, Schwartz JD. Using satellite-based spatiotemporal resolved air temperature exposure to study the association between ambient air temperature and birth outcomes in Massachusetts. Environmental Health Perspectives 2015;123(10):1053-1058. R834798 (2015)
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  • Journal Article Krall JR, Anderson GB, Dominici F, Bell ML, Peng RD. Short-term exposure to particulate matter constituents and mortality in a national study of U.S. urban communities. Environmental Health Perspectives 2013;121(10):1148-1153. R834798 (2013)
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  • Journal Article Krieger N, Waterman PD, Gryparis A, Coull BA. Black carbon exposure more strongly associated with census tract poverty compared to household income among US black, white, and Latino working class adults in Boston, MA (2003-2010). Environmental Pollution 2014;190:36-42. R834798 (Final)
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  • Journal Article Krieger N, Waterman PD, Gryparis A, Coull BA. Black carbon exposure, socioeconomic and racial/ethnic spatial polarization, and the Index of Concentration at the Extremes (ICE). Health & Place 2015;34:215-228. R834798 (Final)
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  • Journal Article Lamoureux DP, Diaz EA, Chung Y, Coull BA, Papapostolou V, Lawrence J, Sato R, Godleski JJ. Effects of fresh and aged vehicular particulate emissions on blood pressure in normal adult male rats. Air Quality, Atmosphere & Health 2013;6(2):407-418. R834798 (2012)
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  • Journal Article Lee HJ, Coull BA, Bell ML, Koutrakis P. Use of satellite-based aerosol optical depth and spatial clustering to predict ambient PM2.5 concentrations. Environmental Research 2012;118:8-15. R834798 (2013)
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  • Journal Article Lee HJ, Kang C-M, Coull BA, Bell ML, Koutrakis P. Assessment of primary and secondary ambient particle trends using satellite aerosol optical depth and ground speciation data in the New England region, United States. Environmental Research 2014;133:103-110. R834798 (2014)
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  • Journal Article Lee HJ, Koutrakis P. Daily ambient NO2 concentration predictions using satellite ozone monitoring instrument NO2 data and land use regression. Environmental Science & Technology 2014;48(4):2305-2311. R834798 (2014)
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  • Journal Article Lee M, Kloog I, Chudnovsky A, Lyapustin A, Wang Y, Melly S, Coull B, Koutrakis P, Schwartz J. Spatiotemporal prediction of fine particulate matter using high-resolution satellite images in the Southeastern US 2003-2011. Journal of Exposure Science & Environmental Epidemiology 2016;26(4):377-384. R834798 (2015)
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  • Journal Article Lee M, Shi L, Zanobetti A, Schwartz JD. Study on the association between ambient temperature and mortality using spatially resolved exposure data. Environmental Research 2016;151:610-617. R834798 (Final)
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  • Journal Article Lee M, Schwartz J, Wang Y, Dominici F, Zanobetti A. Long-term effect of fine particulate matter on hospitalization with dementia. Environmental Pollution 2019;254:112. R834798 (Final)
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  • Journal Article Lee W-C, Shen L, Catalano PJ, Mickley LJ, and Koutrakis P. Effects of Future Temperature Change on PM2.5 Infiltration in the Greater Boston Area. Atmospheric Environment 2017;150:98-105. R834798 (Final)
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  • Journal Article Lemos M, Diaz EA, Gupta T, Kang C-M, Ruiz P, Coull BA, Godleski JJ, Gonzalez-Flecha B. Cardiac and pulmonary oxidative stress in rats exposed to realistic emissions of source aerosols. Inhalation Toxicology 2011;23(Suppl 2):75-83. R834798 (2013)
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  • Journal Article Lepeule J, Laden F, Dockery D, Schwartz J. Chronic exposure to fine particles and mortality: an extended follow-up of the Harvard Six Cities study from 1974 to 2009. Environmental Health Perspectives 2012;120(7):965-970. R834798 (2012)
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  • Journal Article Lepeule J, Baccarelli A, Tarantini L, Motta V, Cantone L, Litonjua AA, Sparrow D, Vokonas PS, Schwartz J. Gene promoter methylation is associated with lung function in the elderly: the Normative Aging Study. Epigenetics 2012;7(3):261-269. R834798 (2012)
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  • Journal Article Lepeule J, Bind M-AC, Baccarelli AA, Koutrakis P, Tarantini L, Litonjua A, Sparrow D, Vokonas P, Schwartz JD. Epigenetic influences on associations between air pollutants and lung function in elderly men: the Normative Aging Study. Environmental Health Perspectives 2014;122( 6):566-572. R834798 (2014)
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  • Journal Article Lepeule J, Litonjua AA, Coull B, Koutrakis P, Sparrow D, Vokonas PS, Schwartz J. Long-term effects of traffic particles on lung function decline in the elderly. American Journal of Respiratory and Critical Care Medicine 2014;190(5):542-548. R834798 (Final)
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  • Journal Article Lepeule J, Litonjua AA, Gasparrini A, Koutrakis P, Sparrow D, Vokonas PS, Schwartz J. Lung function association with outdoor temperature and relative humidity and Its interaction with air pollution in the elderly. Environmental Research 2018;165:110-117. R834798 (Final)
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  • Journal Article Levy JI, Diez D, Dou Y, Barr CD, Dominici F. A meta-analysis and multisite time-series analysis of the differential toxicity of major fine particulate matter constituents. American Journal of Epidemiology 2012;175(11):1091-1099. R834798 (2012)
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  • Journal Article Levy JI, Fabian MP, Peters JL. Meta-analytic approaches for multistressor dose-response function development: strengths, limitations, and case studies. Risk Analysis 2015;35(6):1040-1049. R834798 (Final)
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  • Journal Article Li W, Dorans KS, Wilker EH, Rice MB, Schwartz J, Coull BA, Koutrakis P, Gold DR, Fox CS, Mittleman MA. Residential proximity to major roadways, fine particulate matter, and adiposity: the Framingham Heart Study. Obesity 2016;24(12):2593-2599. R834798 (Final)
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  • Journal Article Li W, Wilker EH, Dorans KS, Rice MB, Schwartz J, Coull BA, Koutrakis P, Gold DR, Keaney JF, Lin H, Vasan RS, Benjamin EJ, Mittleman MA. Short‐term exposure to air pollution and biomarkers of oxidative stress:the Framingham Heart Study. Journal of the American Heart Association 2016;5(5):e002742 (9 pp.). R834798 (Final)
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  • Journal Article Li W, Dorans KS, Wilker EH, Rice MB, Long MT, Schwartz J, Coull BA, Koutrakis P, Gold DR, Fox CS, Mittleman MA. Residential proximity to major roadways, fine particulate matter, and hepatic steatosis: the Framingham Heart Study. American Journal of Epidemiology 2017;186(7):857-865. R834798 (Final)
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  • Journal Article Li W, Dorans KS, Wilker EH, Rice MB, Ljungman PL, Schwartz JD, Coull BA, Koutrakis P, Gold DR, Keaney Jr JF, Vasan RS, Benjamin EJ, Mittleman MA. Short-term exposure to ambient air pollution and biomarkers of systemic inflammation: the Framingham Heart Study. Arteriosclerosis, Thrombosis, and Vascular Biology 2017;37(9):1793-1800. R834798 (Final)
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  • Journal Article Liang D, Lee W, Liao J, Lawence J, Wolfson J, Ebelt S, Kang C, Koutrakis P, Samat J. Estimating climate change-related impacts on outdoor air pollution infiltration. ENVIRONMENTAL RESEARCH 2021;196(110923). R834798 (Final)
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  • Journal Article Link MS, Luttmann-Gibson H, Schwartz J, Mittleman MA, Wessler B, Gold DR, Dockery DW, Laden F. Acute exposure to air pollution triggers atrial fibrillation. Journal of the American College of Cardiology 2013;62(9):816-825. R834798 (2013)
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  • Journal Article Liu JC, Pereira G, Uhl SA, Bravo MA, Bell ML. A systematic review of the physical health impacts from non-occupational exposure to wildfire smoke. Environmental Research 2015;136:120-132. R834798 (Final)
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  • Journal Article Liu JC, Wilson A, Mickley LJ, Dominici F, Ebisu K, Wang Y, Sulprizio MP, Peng RD, Yue X, Son JY, Anderson GB, Bell ML. Wildfire-specific fine particulate matter and risk of hospital admissions in urban and rural counties. Epidemiology 2017;28(1):77-85. R834798 (Final)
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  • Journal Article Liu JC, Wilson A, Mickley LJ, Ebisu K, Sulprizio MP, Wang Y, Peng RD, Yue X, Dominici F, Bell ML. Who among the elderly is most vulnerable to exposure to and health risks of fine particulate matter from wildfire smoke? American Journal of Epidemiology 2017;186(6):730-735. R834798 (Final)
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  • Journal Article Ljungman PL, Wilker EH, Rice MB, Schwartz J, Gold DR, Koutrakis P, Vita JA, Mitchell GF, Vasan RS, Benjamin EJ, Mittleman MA, Hamburg NM. Short-term exposure to air pollution and digital vascular function. American Journal of Epidemiology 2014;180(5):482-489. R834798 (Final)
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  • Journal Article Ljungman PL, Mittleman MA. Ambient air pollution and stroke. Stroke. 2014b;45:3734-3741. R834798C003 (Final)
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    Journal Article Lue S-H, Wellenius GA, Wilker EH, Mostofsky E, Mittleman MA. Residential proximity to major roadways and renal function. Journal of Epidemiology & Community Health 2013;67(8):629-634. R834798 (2013)
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  • Journal Article Maccarone J, Grady S, Moy M, Hart J, Kang C, Coull B, Schwartz J, Koutrakis P, Zhang J, Garshick E. Indoor (residential) and ambient particulate matter associations with urinary oxidative stress biomarkers in a COPD cohort. SCIENCE OF THE TOTAL ENVIRONMENT 2023;165352. R834798 (Final)
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  • Journal Article MacNaughton P, Eitland E, Kloog I, Schwartz J, Allen J. Impact of particular matter exposure and surrounding “greenness” on chronic absenteeism in Massachusetts public schools. International Journal of Environmental Research and Public Health 2017;14(2):E207. R834798 (Final)
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  • Journal Article MacNaughton P, Eitland E, Kloog I, Schwartz J, Allen J. Impact of Particulate Matter Exposure and Surrounding Greenness on Chronic Absenteeism in Massachusetts Public Schools. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH 2017;14(2):207. R834798 (Final)
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  • Journal Article Madrigano J, Baccarelli A, Mittleman MA, Sparrow D, Spiro III A, Vokonas PS, Cantone L, Kubzansky L, Schwartz J. Air pollution and DNA methylation: interaction by psychological factors in the VA Normative Aging Study. American Journal of Epidemiology 2012;176(3):224-232. R834798 (2013)
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  • Journal Article Madrigano J, Kloog I, Goldberg R, Coull BA, Mittleman MA, Schwartz J. Long-term exposure to PM2.5 and incidence of acute myocardial infarction. Environmental Health Perspectives 2013;121(2):192-196. R834798 (2013)
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  • Journal Article Madrigano J, Mittleman MA, Baccarelli A, Goldberg R, Melly S, von Klot S, Schwartz J. Temperature, myocardial infarction, and mortality: effect modification by individual-and area-level characteristics. Epidemiology 2013;24(3):439-446. R834798 (Final)
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  • Journal Article Madrigano J, Jack D, Anderson GB, Bell ML, Kinney PL. Temperature, ozone, and mortality in urban and non-urban counties in the northeastern United States. Environmental Health 2015;14:3 (11 pp.). R834798 (Final)
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  • Journal Article Mannshardt E, Sucic K, Jiao W, Dominici F, Frey HC, Reich B, Fuentes M. Comparing exposure metrics for the effects of fine particulate matter on emergency hospital admissions. Journal of Exposure Science and Environmental Epidemiology 2013;23(6):627-636. R834798 (Final)
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  • Journal Article Masri S, Kang C-M, Koutrakis P. Composition and sources of fine and coarse particles collected during 2002–2010 in Boston, MA. Journal of the Air & Waste Management Association 2015;65(3):287-297. R834798 (2015)
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  • Journal Article Masri S, Garshick E, Hart J, Bouhamra W, Koutrakis P. Use of visual range measurements to predict fine particulate matter exposures in Southwest Asia and Afghanistan. Journal of the Air & Waste Management Association 2017;67(1):75-85. R834798 (Final)
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  • Journal Article Masri S, Garshick E, Coull B, Koutrakis P. A novel calibration approach using satellite and visibility observations to estimate fine particulate matter exposures in Southwest Asia and Afghanistan. Journal of the Air & Waste Management Association 2017;67(1):86-95. R834798 (Final)
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  • Journal Article Matthaios V, Liu M, Li L, Kang M, Vieira C, Gold D, Koutrakis P. Sources of indoor PM2.5 gross alpha and beta activities measured in 340 homes. ENVIRONMENTAL RESEARCH 2021;197. R834798 (Final)
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  • Journal Article Matthaios V, Kang C, Wolfson J, Greco K, Gaffin J, Hauptman M, Cunningham A, Petty C, Lawrence J, Gold D, Koutrakis P. Factors Influencing Classroom Exposures to Fine Particles, Black Carbon, and Nitrogen Dioxide in Inner-City Schools and Their Implications for Indoor Air Quality. ENVIRONMETAL HEALTH PERSPECTIVES 2022;130(4):47005. R834798 (Final)
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  • Journal Article McDevitt JJ, Koutrakis P, Ferguson ST, Wolfson JM, Fabian MP, Martins M, Pantelic J, Milton DK. Development and performance evaluation of an exhaled-breath bioaerosol collector for influenza virus. Aerosol Science and Technology 2013;47(4):444-451. R834798 (2013)
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  • Journal Article McGuinn LA, Ward-Caviness CK, Neas LM, Schneider A, Diaz-Sanchez D, Cascio WE, Kraus WE, Hauser E, Dowdy E, Haynes C, Chudnovsky A, Koutrakis P, Devlin RB. Association between satellite-based estimates of long-term PM2.5 exposure and coronary artery disease. Environmental Research 2016;145:9-17. R834798 (2016)
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  • Journal Article Mehta AJ, Zanobetti A, Koutrakis P, Mittleman MA, Sparrow D, Vokonas P, Schwartz J. Associations between short-term changes in air pollution and correlates of arterial stiffness: the Veterans Affairs Normative Aging Study, 2007-2011. American Journal of Epidemiology 2014;179(2):192-199. R834798 (2014)
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  • Journal Article Mehta AJ, Kubzansky LD, Coull BA, Kloog I, Koutrakis P, Sparrow D, Spiro III A, Vokonas P, Schwartz J. Associations between air pollution and perceived stress: the Veterans Administration Normative Aging Study. Environmental Health 2015;14:10 (10 pp.). R834798 (2015)
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  • Journal Article Mehta AJ, Zanobetti A, Bind MA, Kloog I, Koutrakis P, Sparrow D, Vokonas PS, Schwartz JD. Long-term exposure to ambient fine particulate matter and renal function in older men: the Veterans Administration Normative Aging Study. Environmental Health Perspectives 2016;124(9):1353-1360. R834798 (Final)
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  • Journal Article Mittleman MA, Mostofsky E. Exchangeability in the case-crossover design. International Journal of Epidemiology 2014;43(5):1645-1655. R834798 (2014)
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  • Journal Article Montresor-Lopez JA, Yanosky JD, Mittleman MA, Sapkota A, He X, Hibbert JD, Wirth MD, Puett RC. Short-term exposure to ambient ozone and stroke hospital admission: a case-crossover analysis. Journal of Exposure Science & Environmental Epidemiology 2016;26(2):162-166. R834798 (Final)
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  • Journal Article Mordukhovich I, Lepeule J, Coull BA, Sparrow D, Vokonas P, Schwartz J. The effect of oxidative stress polymorphisms on the association between long-term black carbon exposure and lung function among elderly men. Thorax 2015;70(2):133-137. R834798 (2015)
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  • Journal Article Mordukhovich I, Coull B, Kloog I, Koutrakis P, Vokonas P, Schwartz J. Exposure to sub-chronic and long-term particulate air pollution and heart rate variability in an elderly cohort: the Normative Aging Study. Environmental Health 2015;14:87 (10 pp.). R834798 (Final)
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  • Journal Article Mordukhovich I, Kloog I, Coull B, Koutrakis P, Vokonas P, Schwartz J. Association between particulate air pollution and QT interval duration in an elderly cohort. Epidemiology 2016;27(2):284-290. R834798 (Final)
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  • Journal Article Mordukhovich, I., Coull, B.A., Kloog, I., Koutrakis, P., Vokonas, P., and Schwartz, J. (2015). Exposure to Sub-Chronic and Long-t4erm Particulate Air Pollution and Heart Rate Variability in an Elderly Cohort:the Normative Aging Study. Environmental Health 14, 1-10. R834798C002 (Final)
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    Journal Article Mostofsky E, Schwartz J, Coull BA, Koutrakis P, Wellenius GA, Suh HH, Gold DR, Mittleman MA. Modeling the association between particle constituents of air pollution and health outcomes. American Journal of Epidemiology 2012;176(4):317-326. R834798 (2013)
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  • Journal Article Mostofsky E, Wilker EH, Schwartz J, Zanobetti A, Gold DR, Wellenius GA, Mittleman MA. Short-term changes in ambient temperature and risk of ischemic stroke. Cerebrovascular Diseases Extra 2014;4(1):9-18. R834798 (2014)
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  • Journal Article Mostofsky, E., Schwartz, J., Coull, B., Koutrakis, P., Wellenius, G.A., Suh, H.H., Gold, D.R., and Mittleman, M.A. (2012). Modeling the Association between Particle Constituents of Air Pollution and Health Outcomes. American Journal of Epidemiology 176, 317 – 326. R834798C002 (Final)
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    Journal Article Nguyen JL, Laden F, Link MS, Schwartz J, Luttmann-Gibson H, Dockery DW. Weather and triggering of ventricular arrhythmias in patients with implantable cardioverter-defibrillators. Journal of Exposure Science & Environmental Epidemiology 2015;25(2):175-181. R834798 (2015)
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  • Journal Article Nguyen JL, Link MS, Luttmann-Gibson H, Laden F, Schwartz J, Wessler BS, Mittleman MA, Gold DR, Dockery DW. Drier air, lower temperatures, and triggering of paroxysmal atrial fibrillation. Epidemiology 2015;26(3):374-380. R834798 (2015)
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  • Journal Article Nordio F, Kloog I, Coull BA, Chudnovsky A, Grillo P, Bertazzi PA, Baccarelli AA, Schwartz J. Estimating spatio-temporal resolved PM10 aerosol mass concentrations using MODIS satellite data and land use regression over Lombardy, Italy. Atmospheric Environment 2013;74:227-236. R834798 (2013)
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  • Journal Article Oken E, Baccarelli AA, Gold DR, Kleinman KP, Litonjua AA, De Meo D, Rich-Edwards JW, Rifas-Shiman SL, Sagiv S, Taveras EM, Weiss ST, Belfort MB, Burris HH, Camargo Jr. CA, Huh SY, Mantzoros C, Parker MG, Gillman MW. Cohort profile: Project Viva. International Journal of Epidemiology 2015;44(1):37-48. R834798 (Final)
    R834798C004 (2014)
    R834798C004 (Final)
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  • Journal Article Panni T, Mehta AJ, Schwartz JD, Baccarelli AA, Just AC, Wolf K, Wahl S, Cyrys J, Kunze S, Strauch K, Waldenberger M. Genome-wide analysis of DNA methylation and fine particulate matter air pollution in three study populations: KORA F3, KORA F4, and the Normative Aging Study. Environmental Health Perspectives 2016;124(7):983-990. R834798 (Final)
    R834798C002 (Final)
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  • Journal Article Panni T, Mehta AJ, Schwartz JD, Baccarelli AA, Just AC, Wolf Kr, Wahl S, Cyrys J, Kunze sS, K. R834798 (2016)
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    Journal Article Papapostolou V, Lawrence JE, Diaz EA, Wolfson JM, Ferguson ST, Long MS, Godleski JJ, Koutrakis P. Laboratory evaluation of a prototype photochemical chamber designed to investigate the health effects of fresh and aged vehicular exhaust emissions. Inhalation Toxicology 2011;23(8):495-505. R834798 (2010)
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  • Journal Article Papapostolou V, Lawrence JE, Ferguson ST, Wolfson JM, Diaz EA, Godleski JJ, Koutrakis P. Development and characterization of an exposure generation system to investigate the health effects of particles from fresh and aged traffic emissions. Air Quality, Atmosphere & Health 2013;6(2):419-429. R834798 (2012)
    R834798 (2013)
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  • Journal Article Patton AP, Collins C, Naumova EN, Zamore W, Brugge D, Durant JL. An hourly regression model for ultrafine particles in a near-highway urban area. Environmental Science & Technology 2014;48(6):3272-3280. R834798 (2014)
    R834798 (Final)
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  • Journal Article Peng C, Luttmann-Gibson H, Zanobetti A, Cohen A, De Souza C, Coull BA, Horton ES, Schwartz J, Koutrakis P, Gold DR. Air pollution influences on exhaled nitric oxide among people with type II diabetes. Air Quality, Atmosphere & Health 2016;9(3):265-273. R834798 (Final)
    R832416 (Final)
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  • Journal Article Peng C, Bind MA, Colicino E, Kloog I, Byun HM, Cantone L, Trevisi L, Zhong J, Brennan K, Dereix AE, Vokonas PS, Coull BA, Schwartz JD, Baccarelli AA. Particulate air pollution and fasting blood glucose in nondiabetic individuals: associations and epigenetic mediation in the normative aging study, 2000–2011. Environmental Health Perspectives 2016;124(11):1715-1721. R834798 (Final)
    R834798C002 (Final)
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  • Journal Article Pereira G, Bell ML, Lee HJ, Koutrakis P, Belanger K. Sources of fine particulate matter and risk of preterm birth in Connecticut, 2000–2006: a longitudinal study. Environmental Health Perspectives 2014;122(10):1117-1122. R834798 (2015)
    R834798 (Final)
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  • Journal Article Pereira, G., Bell, M.L., Lee, H.J., Koutrakis, P., and Belanger, K. (2014). Sources of Fine Particulate Matter and Risk of Preterm Birth in Connecticut, 2000–2006:A Longitudinal Study. Environmental Health Perspectives 122, 1117-1122. R834798C005 (Final)
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    Journal Article Peters JL, Kubzansky LD, Ikeda A, Spiro III A, Wright RO, Weisskopf MG, Kim D, Sparrow D, Nie LH, Hu H, Schwartz J. Childhood and adult socioeconomic position, cumulative lead levels, and pessimism in later life: the VA Normative Aging Study. American Journal of Epidemiology 2011;174(12):1345-1353. R834798 (2010)
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  • Journal Article Phipatanakul W, Koutrakis P, Coull BA, Kang CM, Wolfson JM, Ferguson ST, Petty CR, Samnaliev M, Cunningham A, Sheehan WJ, Gaffin JM, Baxi SN, Lai PS, Permaul P, Liang L, Thorne PS, Adamkiewicz G, Brennan KJ, Baccarelli AA, Gold DR. The school inner-city asthma intervention study: design, rationale, methods, and lessons learned. Contemporary Clinical Trials 2017;60:14-23. R834798 (Final)
    R835872 (2016)
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  • Journal Article Powell H, Krall JR, Wang Y, Bell ML, Peng RD. Ambient coarse particulate matter and hospital admissions in the Medicare Cohort Air Pollution Study, 1999-2010. Environmental Health Perspectives 2015;123(11):1152-1158. R834798 (Final)
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  • Journal Article Power, MC, Weisskopf MG, Alexeef SE, Coull BA, Spiro III A , Schwartz J. Traffic-related air pollution and cognitive function in a cohort of older men. Environmental Health Perspectives 2011;119(5):682-687. R834798 (2010)
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  • Journal Article Power MC, Weisskopf MG, Alexeeff SE, Wright RO, Coull BA, Spiro III A, Schwartz J. Modification by hemochromatosis gene polymorphisms of the association between traffic-related air pollution and cognition in older men: a cohort study. Environmental Health 2013;12:16 (8 pp.). R834798 (2014)
    R834798 (Final)
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  • Journal Article Requia Junior WJ, Roig HL, Koutrakis P. A spatial multicriteria model for determining air pollution at sample locations. Journal of the Air & Waste Management Association 2015;65(2):232-243. R834798 (Final)
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  • Journal Article Requia Jr WJ, Koutrakis P, Roig HL. Spatial distribution of vehicle emission inventories in the Federal District, Brazil. Atmospheric Environment 2015;112:32-39. R834798 (Final)
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  • Journal Article Requia WJ, Roig HL, Koutrakis P. A novel land use approach for assessment of human health:The relationship between urban structure types and cardiorespiratory disease risk. Environment International 2015;85:334-342. R834798 (2016)
    R834798 (Final)
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  • Journal Article Requia WJ, Koutrakis P, Roig HL, Adams MD, Santos CM. Association between vehicular emissions and cardiorespiratory disease risk in Brazil and its variation by spatial clustering of socio-economic factors. Environmental Research 2016;150:452-460. R834798 (Final)
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  • Journal Article Requia WJ, Adams MD, Koutrakis P. Association of PM2.5 with diabetes, asthma, and high blood pressure incidence in Canada:a spatiotemporal analysis of the impacts of the energy generation and fuel sales. Science of the Total Environment 2017;584-585:1077-1083. R834798 (Final)
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  • Journal Article Requia WJ, Roig HL, Koutrakis P, Adams MD. Modeling spatial patterns of traffic emissions across 5570 municipal districts in Brazil. Journal of Cleaner Production 2017;148:845-853. R834798 (Final)
    R835872 (2016)
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  • Journal Article Requia WJ, Adams MD, Arain A, Koutrakis P, Lee W-C, Ferguson M. Spatio-temporal analysis of particulate matter intake fractions for vehicular emissions: hourly variation by micro-environments in the Greater Toronto and Hamilton Area, Canada. Science of the Total Environment 2017;599-600:1813-1822. R834798 (Final)
    R835872 (2016)
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  • Journal Article Requia WJ, Dalumpines R, Adams MD, Arain A, Ferguson M, Koutrakis P. Modeling spatial patterns of link-based PM2.5 emissions and subsequent human exposure in a large Canadian metropolitan area. Atmospheric Environment 2017;158:172-180. R834798 (Final)
    R835872 (2016)
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  • Journal Article Requia WJ, Adams MD, Arain A, Koutrakis P, Ferguson M. Carbon dioxide emissions of plug-in hybrid electric vehicles: a life-cycle analysis in eight Canadian cities. Renewable and Sustainable Energy Reviews 2017;78:1390-1396. R834798 (Final)
    R835872 (2016)
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  • Journal Article Requia WJ, Higgins CD, Adams MD, Mohamed M, Koutrakis P. The health impacts of weekday traffic: a health risk assessment of PM2.5 emissions during congested periods. Environment International 2018;111:164-176. R834798 (Final)
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  • Journal Article Requia WJ, Coull BA, Koutrakis P. Regional air pollution mixtures across the continental US. Atmospheric Environment 2019;213(5):258-272. R834798 (Final)
    R835872 (2018)
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  • Journal Article Requia W, Di Q, Silvern R, Kelly J, Koutrakis P, Mickley L, Sulprizio M, Amini H, Schwartz J. An ensemble learning approach for estimating high spatiotemporal resolution of ground-level ozone in the contiguous United States. Environmental Science & Technology 2020;54(18):11037-11047. R834798 (Final)
    R835872 (2020)
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  • Journal Article Rice MB, Ljungman PL, Wilker EH, Gold DR, Schwartz JD, Koutrakis P, Washko GR, O'Connor GT, Mittleman MA. Short-term exposure to air pollution and lung function in the Framingham Heart Study. American Journal of Respiratory and Critical Care Medicine 2013;188(11):1351-1357. R834798 (Final)
    R834798C003 (2014)
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  • Journal Article Rice MB, Thurston GD, Balmes JR, Pinkerton KE. Climate change. A global threat to cardiopulmonary health. American Journal of Respiratory and Critical Care Medicine 2014;189(5):512-519. R834798 (Final)
    R834798C003 (2014)
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  • Journal Article Rice MB, Rifas-Shiman SL, Oken E, Gillman MW, Ljungman PL, Litonjua AA, Schwartz J, Coull BA, Zanobetti A, Koutrakis P, Melly SJ, Mittleman MA, Gold DR. Exposure to traffic and early life respiratory infection: a cohort study. Pediatric Pulmonology 2015;50(3):252-259. R834798 (2014)
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  • Journal Article Rice MB, Rifas-Shiman SL, Litonjua AA, Oken E, Gillman MW, Kloog I, Luttmann-Gibson H, Zanobetti A, Coull BA, Schwartz J, Koutrakis P, Mittleman MA, Gold DR. Lifetime exposure to ambient pollution and lung function in children. American Journal of Respiratory and Critical Care Medicine 2016;193(8):881-888. R834798 (2015)
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  • Journal Article Rodosthenous RS, Coull BA, Lu Q, Vokonas PS, Schwartz JD, Baccarelli AA. Ambient particulate matter and microRNAs in extracellular vesicles: a pilot study of older individuals. Particle and Fibre Toxicology 2016;13:13 (13 pp.). R834798 (2016)
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  • Journal Article Rodosthenous, S., Coull, B.A., Lu, Q., Vokonas, P.S., Schwartz, J.D., and Baccarelli, A.A. (2016). Ambient Particulate Matter and MicroRNAs in Extracellular Vesicles:a Pilot Study of Older Individuals. Particle and Fibre Toxicology 13, 1-13. R834798C002 (Final)
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    Journal Article Romero-Guiterrez C, Koutrakis P, Liu M, Vieria C, Coull B, Maher E, Zhang J, Garshick E. Radon decay product particle radioactivity and oxidative stress biomarkers in patients with COPD. ENVIRONMENTAL RESEARCH 2024;240(Part 2):117505 R834798 (Final)
    R835872 (Final)
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  • Journal Article Rosenbloom JI, Wilker EH, Mukamal KJ, Schwartz J, Mittleman MA. Residential proximity to major roadway and 10-year all-cause mortality after myocardial infarction. Circulation 2012;125(18):2197-2203. R834798 (2012)
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  • Journal Article Schwartz J, Alexeeff SE, Mordukhovich I, Gryparis A, Vokonas P, Suh H, Coull BA. Association between long-term exposure to traffic particles and blood pressure in the Veterans Administration Normative Aging Study. Occupational and Environmental Medicine 2012;69(6):422-427. R834798 (2012)
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  • Journal Article Schwartz J, Austin E, Bind M-A, Zanobetti A, Koutrakis P. Estimating causal associations of fine particles with daily deaths in Boston. American Journal of Epidemiology 2015;182(7):644-650. R834798 (2015)
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  • Journal Article Schwartz J, M-A., Koutrakis P. Estimating causal effects of local air pollution on daily deaths: effect of low levels. Environmental Health Perspectives 2017;125(1):23-29. R834798 (2016)
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  • Journal Article Schwartz, J., Austin, E., Bind, M.A., Zanobetti, A., and Koutrakis, P. (2015). Estimating Causal Associations of Low PM2.5 on Daily Deaths in Boston. American Journal of Epidemiology 182, 644-650. R834798C002 (Final)
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    Journal Article Schwartz, J., and Baccarelli, A.A. (2015). Cardiac Autonomic Dysfunction:Particulate Air Pollution Effects Are Modulated by Epigenetic Immunoregulation of Toll‐like Receptor 2 and Dietary Flavonoid Intake. Journal of the American Heart Association 4. R834798C002 (Final)
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    Journal Article Schwartz, J.B., M-A., and Koutrakis, P. (2016). Estimating Causal Effects of Local Air Pollution on Daily Deaths:Effect of Low Levels. Environmental Health Perspectives http://dx.doi.org/10.1289/EHP232, 1-30. R834798C002 (Final)
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    Journal Article Shi L, Kloog I, Zanobetti A, Liu P, Schwartz JD. Impacts of temperature and its variability on mortality in New England. Nature Climate Change 2015;5:988-991. R834798 (2015)
    R834798 (Final)
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  • Journal Article Shi L, Zanobetti A, Kloog I, Coull BA, Koutrakis P, Melly SJ, Schwartz JD. Low-concentration PM2.5 and mortality:estimating acute and chronic effects in a population-based study. Environmental Health Perspectives 2016;124(1):46-52. R834798 (2015)
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  • Journal Article Shi L, Liu P, Wang Y, Zanobetti A, Kosheleva A, Koutrakis P, Schwartz J. Chronic effects of temperature on mortality in the Southeastern USA using satellite-based exposure metrics. Scientific Reports 2016;6:30161 (8 pp.). R834798 (Final)
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  • Journal Article Shi, L., Liu, P., Kloog, I., Lee, M., Kosheleva, A., and Schwartz, J. (2016). Estimating Daily Air Temperature Across the Southeastern United States Using High-Resolution Satellite Data:A Statistical Modeling Study. Environmental Research 146, 51-58. R834798C002 (Final)
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    Journal Article Shi, L., Zanobetti, A., Kloog, I., Coull, B.A., Koutrakis, P., Melly, S.J., and Schwartz, J. (2015). Low-Concentration PM2.5 and Mortality:Estimating Acute and Chronic Effects in a Population-Based Study. Environmental Health Perspectives 124, 46-52. R834798C002 (Final)
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    Journal Article Shtein A, Kloog I, Schwartz J, Silibello C, Michelozzi P, Gariazzo C, Viegi G, Forastiere F, Karnieli A, Just A, Stafoggia M. Estimating Daily PM2.5 and PM10 over Italy Using an Ensemble Model. ENVIRONMETAL SCIENCE AND TECHNOLOGY 2020;54(1):120-128. R834798 (Final)
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  • Journal Article Sivagangabalan G, Spears D, Masse S, Urch B, Brook RD, Silverman F, Gold DR, Lukic KZ, Speck M, Kusha M, Farid T, Poku K, Shi E, Floras J, Nanthakumar K. The effect of air pollution on spatial dispersion of myocardial repolarization in healthy human volunteers. Journal of the American College of Cardiology 2011;57(2):198-206. R834798 (2012)
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  • Journal Article Sofer T, Maity A, Coull B, Baccarelli A, Schwartz J, Lin X. Multivariate gene selection and testing in studying the exposure effects on a gene set. Statistics in Bioscience 2012;4(2):319-338. R834798 (2013)
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  • Journal Article Sofer T, Baccarelli A, Cantone L, Coull B, Maity A, Lin X, Schwartz J. Exposure to airborne particulate matter is associated with methylation pattern in the asthma pathway. Epigenomics 2013;5(2):147-154. R834798 (2013)
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  • Journal Article Son J-Y, Lee J-T, Park YH, Bell ML. Short-term effects of air pollution on hospital admissions in Korea. Epidemiology 2013;24(4):545-554. R834798 (2013)
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  • Journal Article Son J-Y, Lee J-T, Kim K-H, Jung K, Bell ML. Characterization of fine particulate matter and associations between particulate chemical constituents and mortality in Seoul, Korea. Environmental Health Perspectives 2012;120(6):872-878. R834798 (2013)
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  • Journal Article Son J-Y, Bell ML. The relationships between short-term exposure to particulate matter and mortality in Korea: impact of particulate matter exposure metrics for sub-daily exposures. Environmental Research Letters 2013;8(1):014015. R834798 (2013)
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  • Journal Article Tang CH, Kourakis P, Schwartz J, Coull BA, Di Q. Trends and spatial patterns of fine resolution aerosol optical depth-derived PM2.5 emissions in Northeast United States from 2002 to 2013. Journal of the Air & Waste Management Association 2017;67(1):64-74. R834798 (Final)
    R835872 (2016)
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  • Journal Article Tang CH, Coull BA, Schwartz J, Lyapustin A, Di Q, Koutrakis P. Developing particle emission inventories using remote sensing (PEIRS). Journal of the Air & Waste Management Association 2017;67(1):53-63. R834798 (Final)
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  • Journal Article Valdes A, Zanobetti A, Halonen JI, Cifuentes L, Morata D, Schwartz J. Elemental concentrations of ambient particles and cause specific mortality in Santiago, Chile: a time series study. Environmental Health 2012;11:82 (8 pp.). R834798 (2014)
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  • Journal Article van Rossem L, Rifas-Shiman SL, Melly SJ, Kloog I, Luttmann-Gibson H, Zanobetti A, Coull BA, Schwartz JD, Mittleman MA, Oken E, Gillman MW, Koutrakis P, Gold DR. Prenatal air pollution exposure and newborn blood pressure. Environmental Health Perspectives 2015;123(4):353-359. R834798 (2015)
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  • Journal Article Vieira CL, Koutrakis P, Huang S, Grady S, Hart JE, Coull BA, Laden F, Requia W, Schwartz J, Garshick E. Short-term effects of particle gamma radiation activities on pulmonary function in COPD patients. Environ Res 2019;221-227. R834798 (Final)
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  • Journal Article Vieira C, Koutrakis P. The impact of solar activity on ambient ultrafine particle concentrations:An analysis based on 19-year measurements in Boston, USA. ENVIRONMENTAL RESEARCH 2021;201(111532). R834798 (Final)
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  • Journal Article von Klot S, Zanobetti A, Schwartz J. Influenza epidemics, seasonality, and the effects of cold weather on cardiac mortality. Environmental Health 2012;11:74. R834798 (2013)
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  • Journal Article Waldenberger, M., Peters A. A Genome-Wide Analysis of DNA Methylation and Fine Particulate Matter Air Pollution in Three Study Populations:KORA F3, KORA F4, and the Normative Aging Study. Environmental Health Perspectives 2016; http://dx.doi.org/10.1289/3hp.1509966:1-32. R834798 (2016)
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    Journal Article Wang C, Parmigiani G, Dominici F. Bayesian effect estimation accounting for adjustment uncertainty. Biometrics 2012;68(3):661-671. R834798 (2012)
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  • Journal Article Wang C, Parmigiani G, Dominici F. Rejoinder: Bayesian effect estimation accounting for adjustment uncertainty. Biometrics 2012;68(3):680-686. R834798 (2012)
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  • Journal Article Wang Y, Eliot MN, Koutrakis P, Gryparis A, Schwartz JD, Coull BA, Mittleman MA, Milberg WP, Lipsitz LA, Wellenius GA. Ambient air pollution and depressive symptoms in older adults: results from the MOBILIZE Boston Study. Environmental Health Perspectives 2014;122(6):553-558. R834798 (Final)
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  • Journal Article Wang Y, Eliot MN, Kuchel GA, Schwartz J, Coull BA, Mittleman MA, Lipsitz LA, Wellenius GA. Long-term exposure to ambient air pollution and serum leptin in older adults: results from the MOBILIZE Boston Study. Journal of Occupational and Environmental Medicine 2014;56(9):e73-e77. R834798 (Final)
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  • Journal Article Wang Y, Kloog I, Coull BA, Kosheleva A, Zanobetti A, Schwartz JD. Estimating causal effects of long-term PM2.5 exposure on mortality in New Jersey. Environmental Health Perspectives 2016;124(8):1182-1188. R834798 (2016)
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  • Journal Article Wang Y, Montas HJ, Brubaker KL, Leisnham PT, Shirmohammadi A, Chanse V. A diagnostic decision support system for BMP selection in small urban watershed. Water Resources Management 2017;31(5):1649-1664. R834798C005 (Final)
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  • Journal Article Wang Z, Koutrakis P, Liu M, Vieira C, Coull B, Maher E, Moy M, Huang S, Garshick E. Residential radon decay products are associated with cough and phlegm in patients with COPD. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 2024;282. R834798 (Final)
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  • Journal Article Wang, Y., Eliot, M.N., Koutrakis, P., Gryparis, A., Schwartz, J.D., Coull, B.A., Mittleman, M.A., Milberg, W.P., Lipsitz, L.A., and Wellenius, G.A. (2014). Ambient Air Pollution and Depressive Symptoms in Older Adults:Results from the MOBILIZE Boston Study. Environmental Health Perspectives 122, 553 – 558. R834798C003 (Final)
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    Journal Article Wang, Y., Kloog, I., Coull, B., Kosheleva, A., Zanobetti, A., and Schwartz, J. (2016). Estimating Causal Effects of Long-Term PM2.5 Exposure on Mortality in New Jersey. Environmental Health Perspectives, 1-38. R834798C005 (Final)
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    Journal Article Ward-Caviness CK, Weaver AM, Buranosky M, Pfaff ER, Neas LM, Devlin RB, Schwartz J, Di Q, Cascio WE, Diaz-Sanchez D. Associations Between Long-Term Fine Particulate Matter Exposure and Mortality in Heart Failure Patients. J Am Heart Assoc 2020; 9(6):e012517. R834798 (Final)
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  • Journal Article Wellenius GA, Burger MR, Coull BA, Schwartz J, Suh HH, Koutrakis P, Schlaug G, Gold DR, Mittleman MA. Ambient air pollution and the risk of acute ischemic stroke. Archives of Internal Medicine 2012;172(3):229-234. R834798 (2012)
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  • Journal Article Wellenius GA, Wilhelm-Benartzi CS, Wilker EH, Coull BA, Suh HH, Koutrakis P, Lipsitz LA. Ambient particulate matter and the response to orthostatic challenge in the elderly: the Maintenance of Balance, Independent Living, Intellect, and Zest in the Elderly (MOBILIZE) of Boston study. Hypertension 2012;59(3):558-563. R834798 (2013)
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  • Journal Article Wellenius GA, Boyle LD, Coull BA, Milberg WP, Gryparis A, Schwartz J, Mittleman MA, Lipsitz LA. Residential proximity to nearest major roadway and cognitive function in community-dwelling seniors: results from the MOBILIZE Boston Study. Journal of the American Geriatric Society 2012;60(11):2075-2080. R834798 (2012)
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  • Journal Article Wellenius GA, Boyle LD, Wilker EH, Sorond FA, Coull BA, Koutrakis P, Mittleman MA, Lipsitz LA. Ambient fine particulate matter alters cerebral hemodynamics in the elderly. Stroke 2013;44(6):1532-1536. R834798 (2013)
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  • Journal Article Wellenius, G.A., Boyle, L.D., Coull, B.A., Milberg, W.P., Gryparis, A., Schwartz, J., Mittleman, M.A., and Lipsitz, L.A. (2012a). Residential Proximity to Nearest Major Roadway and Cognitive Function in Community-Dwelling Seniors:Results from the MOBILIZE Boston Study. Journal of the American Geriatric Society 60, 2075–2080. R834798C003 (Final)
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    Journal Article Weuve J, Puett RC, Schwartz J, Yanosky JD, Laden F, Grodstein F. Exposure to particulate air pollution and cognitive decline in older women. Archives of Internal Medicine 2012;172(3):219-227. R834798 (2013)
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  • Journal Article Wikle N, Hanks E, Henneman L, Zigler C. A Mechanistic Model of Annual Sulfate Concentrations in the United States. JOURNALS OF THE AMERICAN STATISTICAL ASSOCIATION 2022;. R834798 (Final)
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  • Journal Article Wilker EH, Yeh G, Wellenius GA, Davis RB, Phillips RS, Mittleman MA. Ambient temperature and biomarkers of heart failure: a repeated measures analysis. Environmental Health Perspectives 2012;120(8):1083-1087. R834798 (2012)
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  • Journal Article Wilker EH, Mostofsky E, Lue S-H, Gold D, Schwartz J, Wellenius GA, Mittleman MA. Residential proximity to high-traffic roadways and poststroke mortality. Journal of Stroke & Cerebrovascular Diseases 2013;22(8):e366-e372. R834798 (2013)
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  • Journal Article Wilker EH, Mittleman MA, Coull BA, Gryparis A, Bots ML, Schwartz J, Sparrow D. Long-term exposure to black carbon and carotid intima-media thickness: the Normative Aging Study. Environmental Health Perspectives 2013;121(9):1061-1067. R834798 (2013)
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  • Journal Article Wilker EH, Wu C-D, McNeely E, Mostofsky E, Spengler J, Wellenius GA, Mittleman MA. Green space and mortality following ischemic stroke. Environmental Research 2014;133:42-48. R834798 (2014)
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  • Journal Article Wilker EH, Ljungman PL, Rice MB, Kloog I, Schwartz J, Gold DR, Koutrakis P, Vita JA, Mitchell GF, Vasan RS, Benjamin EJ, Hamburg NM, Mittleman MA. Relation of long-term exposure to air pollution to brachial artery flow-mediated dilation and reactive hyperemia. American Journal of Cardiology 2014;113(12):2057-2063. R834798 (2014)
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  • Journal Article Wilker EH, Preis SR, Beiser AS, Wolf PA, Au R, Kloog I, Li W, Schwartz J, Koutrakis P, DeCarli C, Seshadri S, Mittleman MA. Long-term exposure to fine particulate matter, residential proximity to major roads and measures of brain structure. Stroke 2015;46(5):1161-1166. R834798 (2015)
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  • Journal Article Wilker EH, Martinez-Ramirez S, Kloog I, Schwartz J, Mostofsky E, Koutrakis P, Mittleman MA, Viswanathan A. Fine particulate matter, residential proximity to major roads, and markers of small vessel disease in a memory study population. Journal of Alzheimer's Disease 2016;53(4):1315-1323. R834798 (Final)
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  • Journal Article Wilker E, Yeh G, Wellenius G, Davis R, Phillips RS, Mittleman M. Ambient Temperature and Bioniarkers of Heart Failure:A Repeated Measures Analysis. ENVIRONMENTAL HEALTH PERSPECTIVES 2012;120(8):1083-1087. R834798 (Final)
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  • Journal Article Wilker E, Mostofsky E, Fossa A, Koutrakis P, Warren A, Charidimou A, Mittleman M, Viswanathan A. Ambient Pollutants and Spontaneous Intracerebral Hemorrhage in Greater Boston. STROKE 2018;49(11):2764-2766. R834798 (Final)
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  • Journal Article Wright L, Rifas-Shiman S, Oken E, Litonjua A, Gold D. Prenatal and Early Life Fructose, Fructose-Containing Beverages, and Midchildhood Asthma. ANNALS OF THE AMERICAN THORACIC SOCIETY 2018;15(2):217-224. R834798 (Final)
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  • Journal Article Wu X, Braun D, Schwartz J, Kioumourtzoglou M, Dominici F. Evaluating the impact of long-term exposure to fine particulate matter on mortality among the elderly. SCIENCE ADVANCES 2020;6(29):eaba5692. R834798 (Final)
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  • Journal Article Yazdi M, Wang Y, Di Q, Zanobetti A, Schwartz J. Long-term exposure to PM2.5 and ozone and hospital admissions of Medicare participants in the Southeast USA. ENVIRONMENTAL INTERNATIONAL 2019;130(104879). R834798 (Final)
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  • Journal Article Yeh RW, Normand S-LT, Wang Y, Barr CD, Dominici F. Geographic disparities in the incidence and outcomes of hospitalized myocardial infarction: does a rising tide lift all boats? Circulation: Cardiovascular Quality and Outcomes 2012;5(2):197-204. R834798 (2012)
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  • Journal Article Yu S, Kang C, Liu M, Kotrakis P. PM2.5 sources affecting particle radioactivity in Boston, Massachusetts. ATHMOSPHERIC ENVIRONMENT 2021;259. R834798 (Final)
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  • Journal Article Zanobetti A, Schwartz J. Ozone and survival in four cohorts with potentially predisposing diseases. American Journal of Respiratory and Critical Care Medicine 2011;184(7):836-841. R834798 (2010)
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  • Journal Article Zanobetti A, O'Neill MS, Gronlund CJ, Schwartz JD. Summer temperature variability and long-term survival among elderly people with chronic disease. Proceedings of the National Academy of Sciences of the United States of America 2012;109(17):6608-6613. R834798 (2012)
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  • Journal Article Zanobetti A, O'Neill MS, Gronlund CJ, Schwartz JD. Susceptibility to mortality in weather extremes: effect modification by personal and small-area characteristics. Epidemiology 2013;24(6):809-819. R834798 (Final)
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  • Journal Article Zanobetti A, Luttmann-Gibson H, Horton ES, Cohen A, Coull BA, Hoffmann B, Schwartz JD, Mittleman MA, Li Y, Stone PH, de Souza C, Lamparello B, Koutrakis P, Gold DR. Brachial artery responses to ambient pollution, temperature, and humidity in people with type 2 diabetes: a repeated-measures study. Environmental Health Perspectives 2014;122(3):242-248. R834798 (2013)
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  • Journal Article Zanobetti A, Coull BA, Gryparis A, Kloog I, Sparrow D, Vokonas PS, Wright RO, Gold DR, Schwartz J. Associations between arrhythmia episodes and temporally and spatially resolved black carbon and particulate matter in elderly patients. Occupational and Environmental Medicine 2014;71(3):201-207. R834798 (2014)
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  • Journal Article Zanobetti A, Dominici F, Wang Y, Schwartz JD. A national case-crossover analysis of the short-term effect of PM2.5 on hospitalizations and mortality in subjects with diabetes and neurological disorders. Environmental Health 2014;13(1):38 (11 pp.). R834798 (Final)
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  • Journal Article Zanobetti A, Austin E, Coull BA, Schwartz J, Koutrakis P. Health effects of multi-pollutant profiles. Environment International 2014;71:13-19. R834798 (Final)
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  • Journal Article Zanobetti A, Peters A. Disentangling interactions between atmospheric pollution and weather. Journal of the Epidemiology and Community Health 2015;69(7):613-615. R834798 (2015)
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  • Journal Article Zanobetti A, Coull BA, Kloog I, Sparrow D, Vokonas PS, Gold DR, Schwartz J. Fine-scale spatial and temporal variation in temperature and arrhythmia episodes in the VA Normative Aging Study. Journal of the Air & Waste Management Association 2017;67(1):96-104. R834798 (Final)
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  • Journal Article Zhong J, Colicino E, Lin X, Mehta A, Kloog I, Zanobetti A, Byun H-M, Bind M-A, Cantone L, Prada D, Tarantini L, Trevisi L, Sparrow D, Vokonas P, Schwartz J, Baccarelli AA. Cardiac autonomic dysfunction: particulate air pollution effects are modulated by epigenetic immunoregulation of Toll‐like receptor 2 and dietary flavonoid intake. Journal of the American Heart Association 2015;4(1):e001423 (21 pp.). R834798 (2015)
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  • Journal Article Zhong J, Urch B, Speck M, Coull BA, Koutrakis P, Thorne PS, Scott J, Liu L, Brook RD, Behbod B, Gibson H, Silverman F, Mittlemanm MA, Baccarelli AA, Gold DR. Endotoxin and β-1,3-d-glucan in concentrated ambient particles induce rapid increase in blood pressure in controlled human exposures. Hypertension 2015;66(3):509-516. R834798 (2016)
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  • Journal Article Zhong J, Cayir A, Trevisi L, Sanchez-Guerra M, Lin X, Peng C, Bind MA, Prada D, Laue H, Brennan KJ, Dereix A, Sparrow D, Vokonas P, Schwartz J, Baccarelli AA. Traffic-related air pollution, blood pressure, and adaptive response of mitochondrial abundance. Circulation 2016;133(4):378-387. R834798 (Final)
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  • Journal Article Zhong J, Trevisi L, Urch B, Lin X, Speck M, Coull BA, Liss G, Thompson A, Wu S, Wilson A, Koutrakis P, Silverman F, Gold DR, Baccarelli AA. B-vitamin supplementation mitigates effects of fine particles on cardiac autonomic dysfunction and inflammation: a pilot human intervention trial. Scientific Reports 2017;7:45322 (9 pp.). R834798C004 (Final)
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  • Journal Article Zhong J, Karlsson O, Wang G, Li J, Guo Y, Lin X, Zemplenyi M, Sanchez-Guerra M, Trevisi L, Urch B, Speck M, Liang L, Coull BA, Koutrakis P, Silverman F, Gold DR, Wu T, Baccarelli AA. B vitamins attenuate the epigenetic effects of ambient fine particles in a pilot human intervention trial. Proceedings of the National Academy of Sciences of the United States of America 2017;114(13):3503-3508. R834798 (Final)
    R834798C004 (Final)
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  • Journal Article Zhong, J., Colicino, E., Lin, X., Mehta, A., Kloog, I., Zanobetti, A., Byun, H.M., Bind, M.A., Cantone, L., Prada, D., Tarantini, L., Trevisi, L., Sparrow, D., Vokonas, P.,. R834798C002 (Final)
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    Journal Article Zigler CM, Dominici F, Wang Y. Estimating causal effects of air quality regulations using principal stratification for spatially correlated multivariate intermediate outcomes. Biostatistics 2012;13(2):289-302. R834798 (2012)
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    R834894 (2013)
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  • Journal Article Zigler CM, Watts K, Yeh RW, Wang Y, Coull BA, Dominici F. Model feedback in Bayesian propensity score estimation. Biometrics 2013;69(1):263-273. R834798 (2013)
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  • Journal Article Zigler CM, Dominici F. Point: clarifying policy evidence with potential-outcomes thinking--beyond exposure-response estimation in air pollution epidemiology. American Journal of Epidemiology 2014;180(12):1133-1140. R834798 (Final)
    R834798C005 (2014)
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  • Journal Article Zigler CM, Dominici F. Uncertainty in propensity score estimation: Bayesian methods for variable selection and model averaged causal effects. Journal of the American Statistical Association 2014;109(505):95-107. R834798 (2014)
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  • Journal Article Vierira CLZ, Link M, Garschick E, Peralta A, Luttman-Gibson H, Laden F, Liu M, Gold D, Koutrakis P. Solar and geomagnetic activity enhance the effects of air pollutants on atrial fibrillation. Eurspace 2022;24(5):713-720. R834798 (Final)
    R835872 (2020)
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  • Journal Article Colicino E, Giuliano G, Power MC, Lepeule J, Wilker EH, Vokonas P, Brennan KJM, Fossati S, Hoxha M, Spiro A, Weisskopf MG, Schwartz J, Baccarelli AA. Long-term Exposure to Black Carbon, Cognition and Single Nucleotide Polymorphisms in MicroRNA Processing Genes in Older Men. Environment International 2016; 88:86-93. R834798 (2016)
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  • Journal Article Kang C-M, Gold D, Koutrakis P. Downwind O3 and PM2.5 speciation during the wildfires in 2002 and 2010. Atmospheric Environment 2014;95:511-519. R834798 (2014)
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  • Journal Article Ljungman PL, Wilker EH, Rice MB, et al. Short-term exposure to air pollution and digital vascular function. Am J Epidemiol. 2014a;180:482-489. R834798C003 (Final)
    R834798C004 (Final)
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  • Journal Article Rice MB, Rifas-Shiman SL, Litonjua AA, Oken E, Gillman MW, Kloog I, Luttmann-Gibson H, Zanobetti A, Coull BA, Schwartz J, Koutrakis P, Mittleman MA and Gold DR. Lifetime Exposure to Ambient Pollution and Lung Function in Children. American Journal of Respiratory and Critical Care Medicine 2016; 193(8):881-888. R834798 (Final)
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  • Journal Article Di Q, Koutrakis P and Schwartz J. A hybrid prediction model for PM2.5 mass and components using a chemical transport model and land use regression. Atmospheric Environment 2016; 131:390-399. R834798 (Final)
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  • Journal Article Shi L, Liu P, Kloog I, Lee M, Kosheleva A, Schwartz J. Estimating daily air temperature across the Southeastern United States using high-resolution satellite data:a statistical modeling study. Environmental Research 2016; 146:51-58. R834798 (2016)
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  • Journal Article Bind M-A, Peters A, Koutrakis P, Coull B, Vokonas P and Schwartz J. Quantile Regression Analysis of the Distributional Effects of Air Pollution on Blood Pressure, Heart Rate Variability, Blood Lipids, and Biomarkers of Inflammation in Elderly American Men:The Normative Aging Study. Environmental Health Perspectives 2016; 124(8):1189-1198. R834798 (Final)
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  • Journal Article Bind M-A, Peters A, Koutrakis P, Coull B, Vokonas P, Schwartz J. Quantile regression analysis of the distributional effects of air pollution on blood pressure, heart rate variability, blood lipids, and biomarkers of inflammation in elderly American men: the Normative Aging Study. Environmental Health Perspectives 2016;124(8):1189-1198. R834798 (2016)
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  • Journal Article Dorans KS, Wilker EH, Li W, et al. Residential proximity to major roads, exposure to fine particulate matter, and coronary artery calcium:The Framingham Heart Study. Arterioscler Thromb Vasc Biol. 2016. R834798C003 (Final)
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  • Journal Article Requia WJ, Roig HL, Koutrakis P and Rossi MS. Mapping alternatives for public policy decision making related to human exposures from air pollution sources in the Federal District, Brazil. Land Use Policy 2016; 59:375-385. R834798 (Final)
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  • Journal Article Réquia WJ, Koutrakis P, Roig HL and Adams MD. Spatiotemporal analysis of traffic emissions in over 5000 municipal districts in Brazil. Journal of the Air & Waste Management Association 2016; 66(12):1284-1293. R834798 (Final)
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  • Journal Article Ierodiakonou D, Zanobetti A, Coull BA, Melly S, Postma DS, Boezen HM, Vonk JM, Williams PV, Shapiro GG, McKone EF, Hallstrand TS, Koenig JQ, Schildcrout JS, Lumley T, Fuhlbrigge AN, Koutrakis P, Schwartz J, Weiss ST and Gold DR. Ambient air pollution, lung function, and airway responsiveness in asthmatic children. Journal of Allergy and Clinical Immunology 2016; 137(2):390-399. R834798 (Final)
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  • Journal Article McGuinn LA, Ward-Caviness CK, Neas LM, Schneider A, Diaz-Sanchez D, Cascio WE, Kraus WE, Hauser E, Dowdy E, Haynes C, Chudnovsky A, Koutrakis P and Devlin RB. Association between satellite-based estimates of long-term PM2.5 exposure and coronary artery disease. Environmental Research 2016; 145:9-17. R834798 (Final)
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  • Journal Article Dai L, Koutrakis P, Coull BA, Sparrow D, Vokonas PS and Schwartz JD. Use of the Adaptive LASSO Method to Identify PM 2.5 Components Associated with Blood Pressure in Elderly Men:The Veterans Affairs Normative Aging Study. Environmental Health Perspectives 2016; 124(1):120-125. R834798 (Final)
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  • Journal Article Lee M, Kloog I, Chudnovsky A, Lyapustin A, Wang Y, Melly S, Coull B, Koutrakis P and Schwartz J. Spatiotemporal prediction of fine particulate matter using high-resolution satellite images in the Southeastern US 2003–2011. Journal of Exposure Science & Environmental Epidemiology 2016; 26(4):377-384. R834798 (Final)
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  • Journal Article Lee M, Koutrakis P, Coull B, Kloog I and Schwartz J. Acute effect of fine particulate matter on mortality in three Southeastern states from 2007–2011. Journal of Exposure Science & Environmental Epidemiology 2016; 26(2):173-179. R834798 (Final)
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  • Journal Article Kioumourtzoglou, M.-A., Schwartz, J., James, P., Dominici, F., and Zanobetti, A. (2016). PM2.5 and Mortality in 207 US Cities:Modification by Temperature and City Characteristics. Epidemiology 27, 221-227. R834798 (Final)
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  • Journal Article Requia WJ, Roig HL, Adams MD, Zanobetti A and Koutrakis P. Mapping distance-decay of cardiorespiratory disease risk related to neighborhood environments. Environmental Research 2016; 151:203-215. R834798 (Final)
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  • Journal Article Requia WJ, Coull BA and Koutrakis P. Where air quality has been impacted by weather changes in the United States over the last 30 years? Atmospheric Environment 2020; 224. R834798 (Final)
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  • Journal Article Lee M-S, LeBouf RF, Son Y-S, Koutrakis P and Christiani DC. Nicotine, aerosol particles, carbonyls and volatile organic compounds in tobacco-and menthol-flavored e-cigarettes. Environmental Health 2017; 16(1):42. R834798 (Final)
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  • Journal Article Zhong J, Trevisi L, Urch B, Lin X, Speck M, Coull BA, Liss G, Thompson A, Wu S, Wilson A, Koutrakis P, Silverman F, Gold DR and Baccarelli AA. B-vitamin Supplementation Mitigates Effects of Fine Particles on Cardiac Autonomic Dysfunction and Inflammation:A Pilot Human Intervention Trial. Scientific Reports 2017; 7(1):45322. R834798 (Final)
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  • Journal Article Wilson A, Chiu YH, Hsu HH, Wright RO, Wright RJ, Coull BA. Potential for bias when estimating critical windows for air pollution in children’s health. American Journal of Epidemiology 2017;186(11):1281-1289. R834798 (Final)
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  • Journal Article Son J-Y, Lee HJ, Koutrakis P and Bell ML. Pregnancy and Lifetime Exposure to Fine Particulate Matter and Infant Mortality in Massachusetts, 2001–2007. American Journal of Epidemiology 2017; 186(11):1268-1276. R834798 (Final)
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  • Journal Article Dominici F, Zigler C. Best practices for gauging evidence of causality in air pollution epidemiology. American Journal of Epidemiology 2017;186(12):1303-1309. R834798 (Final)
    R835872 (2017)
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  • Journal Article Awad YA, Koutrakis P, Coull BA, Schwartz J. A spatio-temporal prediction model based on support vector machine regression: ambient black carbon in three New England States. Environmental Research 2017;159: 427-434. R834798 (Final)
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  • Journal Article Li W, Dorans KS, Wilker EH, et al. Residential proximity to major roadways, fine particulate matter, and hepatic steatosis:The Framingham Heart Study. Am J Epidemiol. 2017. R834798C003 (Final)
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  • Journal Article Gaffin JM, Hauptman M, Petty CR, Sheehan WJ, Lai PS, Wolfson JM, Gold DR, Coull BA, Koutrakis P, Phipatanakul W. Nitrogen dioxide exposure in school classrooms of inner-city children with asthma. Journal of Allergy and Clinical Immunology 2018;141(6):2249-2255. R834798 (Final)
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  • Journal Article Li W, Dorans KS, Wilker EH, Rice MB, Kloog I, Schwartz JD, Koutrakis P, Coull BA, Gold DR, Meigs JB, Fox CS. Ambient air pollution, adipokines, and glucose homeostasis:The Framingham heart study. Environment International 2018;111:14-22. R834798 (Final)
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  • Journal Article Rokoff LB, Rifas-Shiman SL, Coull BA, Cardenas A, Calafat AM, Ye X, Gryparis A, Schwartz J, Sagiv SK, Gold DR, Oken E. Cumulative exposure to environmental pollutants during early pregnancy and reduced fetal growth:the project viva cohort. Environmental Health 2018;17(1):19. R834798 (Final)
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  • Journal Article Di Q, Amini H, Shi L, Kloog I, Silvern R, Kelly J, Sabath MB, Choirat C, Koutrakis P, Lyapustin A, Wang Y. Assessing NO2 concentration and model uncertainty with high spatiotemporal resolution across the contiguous United States using ensemble model averaging. Environmental Science & Technology 2019;54(3):1372-1384. R834798 (Final)
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  • Journal Article Blomberg AJ, Coull BA, Jhun I, Vieira CL, Zanobetti A, Garshick E, Schwartz J, Koutrakis P. Effect modification of ambient particle mortality by radon:a time series analysis in 108 US cities. Journal of the Air & Waste Management Association 2019;69(3):266-276. R834798 (Final)
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  • Journal Article Requia WJ, Coull BA, Koutrakis P. Evaluation of predictive capabilities of ordinary geostatistical interpolation, hybrid interpolation, and machine learning methods for estimating PM2.5 constituents over space. Environmental Research 2019;175:421-433. R834798 (Final)
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  • Journal Article Di Q, Amini H, Shi L, Kloog I, Silvern R, Kelly J, Sabath MB, Choirat C, Koutrakis P, Lyapustin A, Wang Y. An ensemble-based model of PM2.5 concentration across the contiguous United States with high spatiotemporal resolution. Environment International 2019;130:104909. R834798 (Final)
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  • Journal Article Requia WJ, Coull BA, Koutrakis P. Multivariate spatial patterns of ambient PM2.5 elemental concentrations in Eastern Massachusetts. 2019;252:1942-1952.. R834798 (Final)
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  • Journal Article Vieira CL, Alvares D, Blomberg A, Schwartz J, Coull B, Huang S, Koutrakis P. Geomagnetic disturbances driven by solar activity enhance total and cardiovascular mortality risk in 263 US cities. Environmental Health 2019;18(1):83. R834798 (Final)
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    R835872 (2018)
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  • Journal Article Requia WJ, Coull BA, Koutrakis P. The influence of spatial patterning on modeling PM2.5 constituents in Eastern Massachusetts. Science of The Total Environment 2019;682:247-258. R834798 (Final)
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  • Journal Article Requia WJ, Jhun I, Coull BA, Koutrakis P. Climate impact on ambient PM2.5 elemental concentration in the United States:a trend analysis over the last 30 years. Environment International 2019;131:104888. R834798 (Final)
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  • Journal Article Gaskins AJ, Minguez-Alarcon L, Fong KC, Abu Awad Y, Di Q, Chavarro JE, Ford JB, Coull BA, Schwartz J, Kloog I, Attaman J. Supplemental folate and the relationship between traffic-related air pollution and livebirth among women undergoing assisted reproduction. American Journal of Epidemiology 2019;188(9):1595-1604. R834798 (Final)
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  • Journal Article Wei Y, Wang Y, Di Q, Choirat C, Wang Y, Koutrakis P, Zanobetti A, Dominici F and Schwartz JD. Short term exposure to fine particulate matter and hospital admission risks and costs in the Medicare population:time stratified, case crossover study. BMJ 2019; 367:l6258. R834798 (Final)
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  • Journal Article Borge R, Requia WJ, Yague C, Jhun I and Koutrakis P. Impact of weather changes on air quality and related mortality in Spain over a 25year period [1993-2017]. Environ Int 2019; 133(Pt B):105272. R834798 (Final)
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  • Journal Article Wang M, Aaron CP, Madrigano J, Hoffman EA, Angelini E, Yang J, Laine A, Vetterli TM, Kinney PL, Sampson PD, Sheppard LE. Association between long-term exposure to ambient air pollution and change in quantitatively assessed emphysema and lung function. JAMA 2019;322(6):546-556. R834798 (Final)
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  • Journal Article Kang CM, Liu M, Garshick E and Koutrakis P. Indoor particle alpha radioactivity origins in occupied homes. Aerosol Air Qual Res 2020; 20(6). R834798 (Final)
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  • Journal Article Gaffin JM, Hauptman M, Petty CR, Haktanir-Abul M, Gunnlaugsson S, Lai PS, Baxi SN, Permaul P, Sheehan WJ, Wolfson JM, Coull BA, Gold DR, Koutrakis P and Phipatanakul W. Differential Effect of School-Based Pollution Exposure in Children With Asthma Born Prematurely. Chest 2020; 158(4):1361-1363. R834798 (Final)
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  • Journal Article Wang VA, Koutrakis P, Li L, Liu M, Vieira CLZ, Coull BA, Maher EF, Kang CM and Garshick E. Particle radioactivity from radon decay products and reduced pulmonary function among chronic obstructive pulmonary disease patients. Environ Res 2023; 216(Pt 1):114492. R834798 (Final)
    R835872C001 (Final)
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  • Journal Article Peng C, Bind M-A, Colicino E, Kloog I, Byun H-M, Cantione L, Trevisi LZ, J., Brennan K, Dereix AE, Vokonas P, Coull BA, Schwartz J, Baccarelli AA. Particulate Air Pollution and Fasting Blood Glucose in Non-Diabetic Individuals:Associations and E[pigenetic Mediation in the Normative Aging Study, 2000-2011. Environmental Health Perspectives 2016; http://dx.doi.org/10.1289/EHP183:1-34. R834798 (2016)
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    Journal Article Zhong, J., Cayir, A., Trevis, L., Sanchez-Guerra, M., Peng, L.X., Bind, M.A., Prada, D., Laue, H., Brennan, K.J.D., A., Sparrow, D., Vokonas, P., Schwartz, J., and. R834798C002 (Final)
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    Journal Article Wang, Y., Eliot, M.N., Kuchel, G.A., Schwartz, J., Coull, B.A., Mittleman, M.A., Lipsitz, L.A., and Wellenius, G.A. (2014). Long-Term Exposure to Ambient Air Pollution and. R834798C003 (Final)
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    Journal Article Wang, Y., Kloog, I., Coull, B., Kosheleva, A., Zanobetti, A., and Schwartz, J. (2016). Estimating Causal Effects of Long-Term PM2.5 Exposure on Mortality in New Jersey. Environmental Health Perspectives, 1-38. R834798C002 (Final)
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    Journal Article Shi, L., Kloog, I., Zanobetti, A., Liu, P., and Schwartz, J. (2015). Impacts of Temperature and its Variability on Mortality in New England. Nature Climate Change 5, 1-6. R834798C002 (Final)
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    Journal Article Lee, M., Kloog, I., Chudnovsky, A., Lyapustin, A., Wang, Y., Melly, S., Coull, B., Koutrakis, P., and Schwartz, J. (2015). Spatiotemporal Prediction of Fine Particulate Matter using High-resolution Satellite Images in the Southeastern US 2003-2011. J Expos Sci Environ Epidemiol, 1-8. R834798C002 (Final)
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    Journal Article Di, Q., Koutrakis, P., Lyapustin, A., Wang, Y., and Schwartz, J. (2016). Assessing PM2.5 Exposures with High Spatio-Temporal Resolution across the Continental United States. Environmental Science & Technology DOI:10.1021/acs.est.5b06121, 1-35. R834798C002 (Final)
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    Journal Article Dai, L., Koutrakis, P., Coull, B.A., Sparrow, D., Vokonas, P.S., and Schwartz, J. (2015). Use of the Adaptive LASSO method to Identify PM2.5 components Associated with Blood Pressure in Elderly Men:Veterans Affairs Normative Aging Study. Environmental Health Perspectives 121, 120-125. R834798C002 (Final)
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    Journal Article Mehta, A., Kubzansky, L., Coull, B., Kloog, I., Koutrakis, P., Sparrow, D., Spiro, A., Vokonas, P., and Schwartz, J. (2015). Associations Between Air Pollution and Perceived Stress:the Veterans Administration Normative Aging Study. Environmental Health 14, 10. R834798C002 (Final)
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    Journal Article Mordukhovich, I., Lepeule, J., Coull, B.A., Sparrow, D., Vokonas, P., and Schwartz, J. (2015). The Effect of Oxidative Stress Polymorphisms on the Association between Long-term Black Carbon Exposure and Lung Function among Elderly Men. Thorax 70, 133-137. R834798C002 (Final)
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    Journal Article Madrigano, J., Mittleman, M., Baccarelli, A., Goldberg, R., Melly, S.J., Von Klot, S., and Schwartz, J. (2013). Temperature, Myocardial Infarction, and Mortality Effect Modification by Individual-and Area-level Characteristics. Epidemiology 24, 439-446. R834798C002 (Final)
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    Journal Article Wang, Y., Shi, L., Zanobetti, A., and Schwartz, J.D. (2016). Estimating and Projecting the Effect of Cold Waves on Mortality in 209 US Cities. Environment International 94, 141-149. R834798C002 (Final)
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    Journal Article Zhong J, Cayir A, Trevis L, Sanchez-Guerra M, Peng LX, Bind MA, Prada D, Laue H, Brennan KJD, A., Sparrow D, Vokonas P, Schwartz J, Baccarelli AA. Traffic Related Air Pollution, Blood Pressure, and Adaptive Response of Mitochondrial Abundance. Circulation 2015; CIRCULATIONAHA.115.018802. R834798 (2016)
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    Journal Article Mannshardt, E., Sucic, K., Jiao, W., Dominici, F., Frey, C.H., Reich, B., and Fuentes, M. (2013). Comparing Exposure Metrics for the Effects of Fine Particulate Matter on Emergency Hospital Admissions. Journal of Exposure Science and Environmental Epidemiology 23, 627–636. R834798C005 (Final)
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    Journal Article Dominici, F., Wang, Y., Correia, A.W., Ezzati, M., Pope, C.A.I., and Dockery, D.W. (2015). Chemical Composition of Fine Particulate Matter and Life Expectancy in 95 US Counties Between 2002 and 2007. Epidemiology 26, 556-564. R834798C005 (Final)
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    Journal Article Ierodiakonou, D., Zanobetti, A., Coull, B., Melly, S., Postma, D.S., Boezen, H.M., Vonk, J.M., Williams, P.V., Shapiro, G.G., McKone, E.F., Hallstrand, T.S., Koenig, J.Q., Schildcrout, J.S., Lumley, T., Fuhlbrigge, A.N., Koutrakis, P., Schwartz, J., Weiss, S.T., and Gold, D.R. (2016). Ambient Air Pollution, Lung Function, and Airway Responsiveness in Asthmatic Children. Journal of Allergy and Clinical Immunology 137, 390-399. R834798C005 (Final)
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    Journal Article Kloog, I., Zanobetti, A., Nordio, F., Coull, B., Baccarelli, A., and Schwartz, J. (2015). Effects of Airborne Fine Particles (PM2.5) on Deep Vein Thrombosis Admissions in the Northeastern United States. Journal of Thrombosis and AHaemostasis 13, 768-774. R834798 (Final)
    R834798C002 (Final)
    R834798C005 (Final)
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    Journal Article Dominici, F., and Mittleman, M. (2012). China's Dilemma:Reconciling Economic Growth with Environmental Protection. Journal of the American Medical Association 307, 2100-2012. R834798C005 (Final)
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    Journal Article Bind, M.-A., Peters, A., Koutrakis, P., Coull, B., Vokonas, P., and Schwartz, J. (2016). Quantile Regression Analysis of the Distributional Effects of Air Pollution on Blood Pressure, Heart Rate Variability, Blood Lipids, and Biomarkers of Inflammation in Elderly American Men:The Normative Aging Study. Environmental Health Perspectives http://doi.org/10.1289/ehp.1510044, 1-34. R834798C002 (Final)
    R834798C005 (Final)
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    Journal Article Harris MH, Gold DR, Rifas-Shiman SL, Melly SJ, Zanobetti A, Coull BA, Schwartz JD, Gryparis A, Kloog I, Koutrakis P, Bellinger DC, White RF, Belfort MB, Webster TF,. R834798C004 (Final)
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    Journal Article Colicino E, Wilson A, Frisardi MC, Prada D, Power MC, Hoxha M, Dioni L, Spiro A III, Vokonas PS, Weisskopf MG, Schwartz JD, Baccarelli AA. 2017. Telomere length, long-term black carbon exposure, and cognitive function in a cohort of older men:the VA Normative Aging Study. Environ Health Perspect 125:76–81; http://dx.doi.org/10.1289/EHP241; Erratum:http://dx.doi.org/10.1289/EHP1813. R834798C002 (Final)
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    Journal Article Baccarelli, A.A. (2016). Long-term Exposure to Black Carbon, Cognition and Single Nucleotide Polymorphisms in MicroRNA Processing Genes in Older Men. Environment International 88, 86-93. R834798C002 (Final)
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    Journal Article Wellenius, G.A., Wilhelm-Benartzi, C.S., Wilker, E.H., Coull, B.A., Suh, H.H., Koutrakis, P., and Lipsitz, L.A. (2012c). Ambient Particulate Matter and the Response to Orthostatic Challenge in the Elderly:The Maintenance of Balance, Independent Living, Intellect, and Zest in the Elderly (MOBILIZE) of Boston Study. Hypertension 59, 558-563. R834798C003 (Final)
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    Journal Article Peng C, Luttmann-Gibson H, Zanobetti A, Cohen A, De Souza C, Coull BA, Horton ES, Schwartz J, Koutrakis P, Gold DR. Air pollution influences on exhaled nitric oxide among people with type 2 diabetes. Air Quality, Atmosphere and Health. http://link.springer.com/article/10.1007%2Fs11869-015-0336-5Mar 26, 2015. R834798C004 (Final)
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    Journal Article Mordukhovich I, Coull BA, Kloog I, Koutrakis P, Vokonas P, Schwartz J. Association between Particulate Air Pollution and QT Interval Duration in an Elderly Cohort. Epidemiol, 2016 Mar;27(2):284-90. doi:10.1097/EDE.0000000000000424. R834798C002 (Final)
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    Journal Article Cole, T.B., J.C. Fisher, T.M. Burbacher, L.G. Costa, and C.E. Furlong, Neurobehavioral assessment of mice following repeated postnatal exposure to chlorpyrifos-oxon. Neurotoxicol Teratol, 2012. 34(3):p. 311-322. R834798C003 (Final)
    R834514C004 (Final)
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    Journal Article Dai L, Bind M-A, Koutrakis P, Coull BA, Sparrow D, Vokonas PS, Schwartz JD. Fine particles, genetic pathways, and markers of inflammation and endothelial dysfunction:Analysis on particulate species and sources. J Expos Sci Environ Epidemiol 2016. R834798 (2016)
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    Journal Article Lee, M.H., Koutrakis, P., Coull, B.A., Kloog, I., and Schwartz, J. (2015). Acute Effects of Fine Particulate Matter on Mortality in Three Southeastern States from 2007-2011. Journal of Exposure Science and Environmental Epidemiology, 1-7. R834798C002 (Final)
    R834798C005 (Final)
    not available
    Journal Article Wilker, E.H., Yeh, G., Wellenius, G.A., Davis, R.B., Phillips, R.S., and Mittleman, M.A. (2012). Ambient Temperature and Biomarkers of Heart Failure:A Repeated Measures Analysis. Environmental Health Perspectives 120, 1083 – 1087. R834798C003 (Final)
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    Journal Article Wilker, E.H., Preis, S.R., Beiser, A.S., Wolf, P.A., Au, R., Kloog, I., Li, W., Schwartz, J., Koutrakis, P., DeCarli, C., Seshadri, S., and Mittleman, M.A. (2015). Long-Term Exposure to Fine Particulate Matter, Residential Proximity to Major Roads and Measures of Brain Structure. Stroke 46, 1161-1166. R834798C002 (Final)
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    Journal Article Lee, M.H., Koutrakis, P., Coull, B.A., Kloog, I., and Schwartz, J. (2015). Acute Effects of Fine Particulate Matter on Mortality in Three Southeastern States from 2007-2011. Journal of Exposure Science and Environmental Epidemiology, 1-7. R834798C002 (Final)
    R834798C005 (Final)
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    Journal Article Raimundo RD, Godleski JJ. Heart rate variability in metabolic syndrome. Journal of Human Growth and Development. 2015; 25(1):7-10. R834798C001 (Final)
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    Journal Article Serum Leptin in Older Adults:Results from the MOBILIZE Boston Study. Journal of Occupational and Environmental Medicine 56, e73-e77. R834798C003 (Final)
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    Journal Article Rice MB, Ljungman PL, Wilker EH, et al. Long-term exposure to traffic emissions and fine particulate matter and lung function decline in the Framingham Heart Study. Am J Respir Crit Care Med. 2015;191:656-664. R834798C003 (Final)
    R834798C004 (Final)
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    Journal Article Kioumourtzoglou M-A, Schwartz J, James P, Dominici F, Zanobetti A. PM2.5 and Mortality in 207 US Cities:Modification by Temperature and City Characteristics. Epidemiology 2016; 27:221-227. R834798 (2016)
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    Journal Article Fleisch A, Luttmann-Gibson H, Perng W, Rifas-Shiman S, Coull BA, Kloog I, Koutrakis P, Schwartz J, Zanobetti A, Mantzoros C, Gillman M, Gold DR, Oken E. Prenatal and Early Life Exposure to Traffic Pollution and Cardiometabolic Health in Childhood. Pediatric Obesity 2016; doi:10.1111/ijpo.12106:1-10. R834798 (2016)
    R834798C004 (Final)
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    Journal Article Harris MH, Gold DR, Rifas-Shiman SL, Melly SJ, Zanobetti A, Coull BA, Schwartz JD, Gryparis A, Kloog I, Koutrakis P, Bellinger DC, White RF, Sagiv SK, Oken E. Prenatal and childhood exposure to traffic-related pollution and childhood cognition. Environ Health Perspect. 2015. Apr 3. [Epub ahead of print]. PMID:25839914. R834798C004 (Final)
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    Journal Article van Rossem L, Melly S, Rifas-Shiman SL, Melly S, Kloog I, Luttmann-Gibson H, Zanobetti A, Coull B, Schwartz J, Mittleman M, Oken E, Gillman M, Koutrakis P, Gold DR. Prenatal exposure to air pollution and newborn blood pressure. Environ Health Perspect. 2015. Apr;123(4):353-9. doi:10.1289/ehp.1307419. Epub 2015 Jan 27.PMID:25625652. R834798C004 (Final)
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    Journal Article Fleisch AF, Rifas-Shiman SL, Koutrakis P, Schwartz J , Kloog I, Melly S, Coull B, Zanobetti A, Gillman M, Gold DR, Oken E. Prenatal exposure to traffic pollution:associations with reduced fetal growth and rapid infant weight gain. Epidemiology. 2015 Jan;26(1):43-50. doi:10.1097/EDE.0000000000000203.PMID:25437317. R834798C004 (Final)
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    Journal Article Li W, Dorans KS, Wilker EH, et al. Residential proximity to major roadways, fine particulate matter, and adiposity:The Framingham Heart Study. Obesity. 2016a;24:2593-2599. R834798C003 (Final)
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    Journal Article Schildcrout, J.S., Lumley, T., Fuhlbrigge, A.N., Koutrakis, P., Schwartz, J., Weiss, S.T., and Gold, D.R. (2016). Ambient Air Pollution, Lung Function, and Airway Responsiveness in Asthmatic Children. Journal of Allergy and Clinical Immunology 137, 390-399. R834798C005 (Final)
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    Journal Article Li W, Wilker EH, Dorans K, Rice MB, Schwartz J, Coull B, Koutrakis P, Gold DR, Keaney JFJ, Lin H, Vasan R, Benjamin EJ, Mittleman MA. Short-Term Exposure to Air Pollution and Biomarkers of Oxidative Stress:The Framingham Heart Study. JournAL Of the American Heart Association 2016; DOI:10.1161/JAHA.115.002742:1-8. R834798 (2016)
    R834798C003 (Final)
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    Journal Article Ljungman PL, Wilker EH, Rice MB, Austin E, Schwartz J, Gold DR, Koutrakis P, Benjamin EJ, Vita JA, Mitchell GF, Vasan RS, Hamburg NM, Mittleman MA. The Impact of Multipollutant Clusters on the Association Between Fine Particulate Air Pollution and Microvascular Function. Epidemiology 2016; 27:194-201. R834798 (2016)
    R834798C003 (Final)
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    Supplemental Keywords:

    Scientific Discipline, Air, air toxics, Environmental Chemistry, Health Risk Assessment, Air Pollution Effects, Biochemistry, Environmental Monitoring, Biology, ambient air quality, children's health, complex mixtures, health effects, particulates, sensitive populations, aerosol particles, air pollutants, biological sensitivities, exposure and effects, lung epithelial cells, susceptible populations, chemical composition, neurotoxicity, human exposure, toxicity, coronary artery disease, cardiopulmonary, cardiotoxicity, environmental effects, human health, mortality

    Relevant Websites:

    http://www.hsph.harvard.edu/clarc/index.html Exit

    Progress and Final Reports:

    Original Abstract
  • 2011 Progress Report
  • 2012 Progress Report
  • 2013 Progress Report
  • 2014 Progress Report
  • 2015 Progress Report
  • Final Report
  • Subprojects under this Center: (EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
    R834798C001 Relative Toxicity of Air Pollution Mixtures
    R834798C002 Cognitive Decline, Cardiovascular Changes, and Biological Aging in Response to Air Pollution
    R834798C003 Identifying the Cognitive and Vascular Effects of Air Pollution Sources and Mixtures in the Framingham Offspring and Third Generation Cohorts
    R834798C004 Longitudinal Effects of Multiple Pollutants on Child Growth, Blood Pressure and Cognition
    R834798C005 A National Study to Assess Susceptibility, Vulnerability, and Effect Modification of Air Pollution Health Risks

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    The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

    Project Research Results

    • Final Report
    • 2015 Progress Report
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    476 publications for this center
    411 journal articles for this center

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